Gene Review:
Epo - erythropoietin
Rattus norvegicus
Synonyms:
Erythropoietin
Grasso,
Sfacteria,
Passalacqua,
Morabito,
Buemi,
Macrì,
Brines,
Tomasello,
Nishiya,
Omura,
Shimada,
Matsumoto,
Kusuyama,
Enomoto,
Iwao,
Takeuchi,
Yoshikawa,
Yoshiyama,
Martínez-Estrada,
Rodríguez-Millán,
González-De Vicente,
Reina,
Vilaró,
Fabre,
Spandou,
Papoutsopoulou,
Soubasi,
Karkavelas,
Simeonidou,
Kremenopoulos,
Guiba-Tziampiri,
- Apaf-1, Bcl-xL, cytochrome c, and caspase-9 form the critical elements for cerebral vascular protection by erythropoietin. Chong, Z.Z., Kang, J.Q., Maiese, K. J. Cereb. Blood Flow Metab. (2003)
- Erythropoietin receptor is expressed on adult rat dopaminergic neurons and erythropoietin is neurotrophic in cultured dopaminergic neuroblasts. Csete, M., Rodriguez, L., Wilcox, M., Chadalavada, S. Neurosci. Lett. (2004)
- Effects of erythropoietin on cardiac remodeling after myocardial infarction. Nishiya, D., Omura, T., Shimada, K., Matsumoto, R., Kusuyama, T., Enomoto, S., Iwao, H., Takeuchi, K., Yoshikawa, J., Yoshiyama, M. J. Pharmacol. Sci. (2006)
- In vivo evidence that erythropoietin protects neurons from ischemic damage. Sakanaka, M., Wen, T.C., Matsuda, S., Masuda, S., Morishita, E., Nagao, M., Sasaki, R. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Erythropoietin improves long-term spatial memory deficits and brain injury following neonatal hypoxia-ischemia in rats. Kumral, A., Uysal, N., Tugyan, K., Sonmez, A., Yilmaz, O., Gokmen, N., Kiray, M., Genc, S., Duman, N., Koroglu, T.F., Ozkan, H., Genc, K. Behav. Brain Res. (2004)
- Mechanism of the decreased erythropoiesis in the water deprived rat. Giglio, J.M., Alippi, R.M., Barceló, A.C., Bozzini, C.E. Br. J. Haematol. (1979)
- Maze learning impairment is associated with stress hemopoiesis induced by chronic treatment of aged rats with human recombinant erythropoietin. Rifkind, J.M., Abugo, O.O., Peddada, R.R., Patel, N., Speer, D., Balagopalakrishna, C., Danon, D., Ingram, D.K., Spangler, E.L. Life Sci. (1999)
- Intracerebroventricular injection of erythropoietin enhances sleep in the rat. García-García, F., Krueger, J.M. Brain Res. Bull. (2003)
- Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Digicaylioglu, M., Lipton, S.A. Nature (2001)
- Hepatic regeneration and erythropoietin production in the rat. Naughton, B.A., Kaplan, S.M., Roy, M., Burdowski, A.J., Gordon, A.S., Piliero, S.J. Science (1977)
- Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis. Villa, P., Bigini, P., Mennini, T., Agnello, D., Laragione, T., Cagnotto, A., Viviani, B., Marinovich, M., Cerami, A., Coleman, T.R., Brines, M., Ghezzi, P. J. Exp. Med. (2003)
- A novel protective effect of erythropoietin in the infarcted heart. Parsa, C.J., Matsumoto, A., Kim, J., Riel, R.U., Pascal, L.S., Walton, G.B., Thompson, R.B., Petrofski, J.A., Annex, B.H., Stamler, J.S., Koch, W.J. J. Clin. Invest. (2003)
- Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model. Ruscher, K., Freyer, D., Karsch, M., Isaev, N., Megow, D., Sawitzki, B., Priller, J., Dirnagl, U., Meisel, A. J. Neurosci. (2002)
- Effects of antioxidant vitamins on renal and hepatic erythropoietin production. Jelkmann, W., Pagel, H., Hellwig, T., Fandrey, J. Kidney Int. (1997)
- Neuroprotective effects of erythropoietin on glutamate and nitric oxide toxicity in primary cultured retinal ganglion cells. Yamasaki, M., Mishima, H.K., Yamashita, H., Kashiwagi, K., Murata, K., Minamoto, A., Inaba, T. Brain Res. (2005)
- A novel site of erythropoietin production. Oxygen-dependent production in cultured rat astrocytes. Masuda, S., Okano, M., Yamagishi, K., Nagao, M., Ueda, M., Sasaki, R. J. Biol. Chem. (1994)
- Functional significance of erythropoietin receptor expression in breast cancer. Arcasoy, M.O., Amin, K., Karayal, A.F., Chou, S.C., Raleigh, J.A., Varia, M.A., Haroon, Z.A. Lab. Invest. (2002)
- Erythropoietin and erythropoietin receptor expression after experimental spinal cord injury encourages therapy by exogenous erythropoietin. Grasso, G., Sfacteria, A., Passalacqua, M., Morabito, A., Buemi, M., Macrì, B., Brines, M.L., Tomasello, F. Neurosurgery (2005)
- Erythropoietin inhibits calcium-induced neurotransmitter release from clonal neuronal cells. Kawakami, M., Iwasaki, S., Sato, K., Takahashi, M. Biochem. Biophys. Res. Commun. (2000)
- EPO receptor-mediated ERK kinase and NF-kappaB activation in erythropoietin-promoted differentiation of astrocytes. Lee, S.M., Nguyen, T.H., Park, M.H., Kim, K.S., Cho, K.J., Moon, D.C., Kim, H.Y., Yoon, d.o. .Y., Hong, J.T. Biochem. Biophys. Res. Commun. (2004)
- Erythropoietin protects the in vitro blood-brain barrier against VEGF-induced permeability. Martínez-Estrada, O.M., Rodríguez-Millán, E., González-De Vicente, E., Reina, M., Vilaró, S., Fabre, M. Eur. J. Neurosci. (2003)
- Erythropoietin after focal cerebral ischemia activates the Janus kinase-signal transducer and activator of transcription signaling pathway and improves brain injury in postnatal day 7 rats. Sola, A., Rogido, M., Lee, B.H., Genetta, T., Wen, T.C. Pediatr. Res. (2005)
- Astroglial cytoprotection by erythropoietin pre-conditioning: implications for ischemic and degenerative CNS disorders. Diaz, Z., Assaraf, M.I., Miller, W.H., Schipper, H.M. J. Neurochem. (2005)
- Erythropoietin gene transfer into rat testes by in vivo electropo-ration may reduce the risk of germ cell loss caused by cryptorchidism. Dobashi, M., Goda, K., Maruyama, H., Fujisawa, M. Asian J. Androl. (2005)
- Hypoxic stress tolerance of the blind subterranean mole rat: expression of erythropoietin and hypoxia-inducible factor 1 alpha. Shams, I., Avivi, A., Nevo, E. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Erythropoietin prevents early and late neuronal demise through modulation of Akt1 and induction of caspase 1, 3, and 8. Chong, Z.Z., Lin, S.H., Kang, J.Q., Maiese, K. J. Neurosci. Res. (2003)
- Post-secretion neutralization of transgene-derived effect: soluble erythropoietin receptor/IgG1Fc expressed in liver neutralizes erythropoietin produced in muscle. Maruyama, H., Higuchi, M., Higuchi, N., Kameda, S., Saito, M., Sugawa, M., Matsuzaki, J., Neichi, T., Yokoyama, S., Miyazaki, Y., Miyazaki, J., Gejyo, F. The journal of gene medicine. (2004)
- Hypoxia-ischemia affects erythropoietin and erythropoietin receptor expression pattern in the neonatal rat brain. Spandou, E., Papoutsopoulou, S., Soubasi, V., Karkavelas, G., Simeonidou, C., Kremenopoulos, G., Guiba-Tziampiri, O. Brain Res. (2004)