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MeSH Review

Ossification, Heterotopic

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Analytical, diagnostic and therapeutic context of Ossification, Heterotopic


  1. Progressive osseous heteroplasia. Kaplan, F.S., Shore, E.M. J. Bone Miner. Res. (2000) [Pubmed]
  2. Immunohistochemical characterization of the small proteoglycans decorin and proteoglycan-100 in heterotopic ossification. Bosse, A., Kresse, H., Schwarz, K., Müller, K.M. Calcif. Tissue Int. (1994) [Pubmed]
  3. Parathyroid hormone-related protein in gastric cancers with heterotopic ossification. Yamamura-Idei, Y., Kitazawa, S., Kitazawa, R., Fujimori, T., Chiba, T., Maeda, S. Cancer (1993) [Pubmed]
  4. Heterotopic ossification and pseudoarthrosis in the shoulder following encephalitis. A case report and review of the literature. An, H.S., Ebraheim, N., Kim, K., Jackson, W.T., Kane, J.T. Clin. Orthop. Relat. Res. (1987) [Pubmed]
  5. Limitation of flexor tendon excursion by heterotopic ossification after isolated flexor tendon laceration. Lorio, M.P., Duplechain, M. Journal of orthopaedic trauma. (2001) [Pubmed]
  6. Genomewide linkage and linkage disequilibrium analyses identify COL6A1, on chromosome 21, as the locus for ossification of the posterior longitudinal ligament of the spine. Tanaka, T., Ikari, K., Furushima, K., Okada, A., Tanaka, H., Furukawa, K., Yoshida, K., Ikeda, T., Ikegawa, S., Hunt, S.C., Takeda, J., Toh, S., Harata, S., Nakajima, T., Inoue, I. Am. J. Hum. Genet. (2003) [Pubmed]
  7. Fibrodysplasia ossificans progressiva, a heritable disorder of severe heterotopic ossification, maps to human chromosome 4q27-31. Feldman, G., Li, M., Martin, S., Urbanek, M., Urtizberea, J.A., Fardeau, M., LeMerrer, M., Connor, J.M., Triffitt, J., Smith, R., Muenke, M., Kaplan, F.S., Shore, E.M. Am. J. Hum. Genet. (2000) [Pubmed]
  8. Bone morphogenetic protein receptors and activin receptors are highly expressed in ossified ligament tissues of patients with ossification of the posterior longitudinal ligament. Yonemori, K., Imamura, T., Ishidou, Y., Okano, T., Matsunaga, S., Yoshida, H., Kato, M., Sampath, T.K., Miyazono, K., ten Dijke, P., Sakou, T. Am. J. Pathol. (1997) [Pubmed]
  9. Deletion mutants of BMP folding variants act as BMP antagonists and are efficient inhibitors for heterotopic ossification. Weber, F.E., Schmökel, H., Oelgeschläger, M., Nickel, J., Maly, F.E., Hortschansky, P., Grätz, K.W. J. Bone Miner. Res. (2003) [Pubmed]
  10. Heterotopic ossification of degenerating rat skeletal muscle induced by adenovirus-mediated transfer of bone morphogenetic protein-2 gene. Gonda, K., Nakaoka, T., Yoshimura, K., Otawara-Hamamoto, Y., Harrii, K. J. Bone Miner. Res. (2000) [Pubmed]
  11. The effect of diphosphonates on heterotopic ossification in regenerating Achilles tendon of the mouse. McClure, J. J. Pathol. (1983) [Pubmed]
  12. Early changes in prostaglandins precede bone formation in a rabbit model of heterotopic ossification. Bartlett, C.S., Rapuano, B.E., Lorich, D.G., Wu, T., Anderson, R.C., Tomin, E., Hsu, J.F., Lane, J.M., Helfet, D.L. Bone (2006) [Pubmed]
  13. Indomethacin compared with localized irradiation for the prevention of heterotopic ossification following surgical treatment of acetabular fractures. Burd, T.A., Lowry, K.J., Anglen, J.O. The Journal of bone and joint surgery. American volume. (2001) [Pubmed]
  14. Disodium etidronate in the prevention of postoperative recurrence of heterotopic ossification in spinal-cord injury patients. Stover, S.L., Niemann, K.M., Miller, J.M. The Journal of bone and joint surgery. American volume. (1976) [Pubmed]
  15. Effect of ibuprofen on heterotopic ossification after hip replacement. Elmstedt, E., Lindholm, T.S., Nilsson, O.S., Törnkvist, H. Acta orthopaedica Scandinavica. (1985) [Pubmed]
  16. Histocompatibility antigens in patients with ectopic ossification due to fibrodysplasia ossificans progressiva. Connor, J.M., Woodrow, J.C., Evans, D.A. Ann. Rheum. Dis. (1982) [Pubmed]
  17. Complete regeneration of bone in the baboon by recombinant human osteogenic protein-1 (hOP-1, bone morphogenetic protein-7). Ripamonti, U., Van Den Heever, B., Sampath, T.K., Tucker, M.M., Rueger, D.C., Reddi, A.H. Growth Factors (1996) [Pubmed]
  18. Radiation-induced suppression of the Bmp2 signal transduction pathway in the pluripotent mesenchymal cell line C2C12: an in vitro model for prevention of heterotopic ossification by radiotherapy. Pohl, F., Hassel, S., Nohe, A., Flentje, M., Knaus, P., Sebald, W., Koelbl, O. Radiat. Res. (2003) [Pubmed]
  19. Deep venous thrombosis associated with heterotopic ossification. Bradleigh, L.H., Perkash, A., Linder, S.H., Sullivan, G.H., Bhatt, H.K., Perkash, I. Archives of physical medicine and rehabilitation. (1992) [Pubmed]
  20. Comparison of human osteoblasts and osteogenic cells from heterotopic bone. Kaysinger, K.K., Ramp, W.K., Lang, G.J., Gruber, H.E. Clin. Orthop. Relat. Res. (1997) [Pubmed]
  21. Diphosphonate treatment for heterotopic ossification in spinal cord injury patients. Garland, D.E., Alday, B., Venos, K.G., Vogt, J.C. Clin. Orthop. Relat. Res. (1983) [Pubmed]
  22. Acute lymphocytic infiltration in an extremely early lesion of fibrodysplasia ossificans progressiva. Gannon, F.H., Valentine, B.A., Shore, E.M., Zasloff, M.A., Kaplan, F.S. Clin. Orthop. Relat. Res. (1998) [Pubmed]
  23. In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification. Glaser, D.L., Economides, A.N., Wang, L., Liu, X., Kimble, R.D., Fandl, J.P., Wilson, J.M., Stahl, N., Kaplan, F.S., Shore, E.M. The Journal of bone and joint surgery. American volume. (2003) [Pubmed]
  24. Regulation of BMP-induced ectopic bone formation by Ahsg. Rittenberg, B., Partridge, E., Baker, G., Clokie, C., Zohar, R., Dennis, J.W., Tenenbaum, H.C. J. Orthop. Res. (2005) [Pubmed]
  25. Noncollagenous proteins in heterotopic ossification. Immunohistochemical analysis in 15 paraplegies. Bosse, A., Wuisman, P., Jones, D.B., Schwarz, K. Acta orthopaedica Scandinavica. (1993) [Pubmed]
  26. Localization of the gene for fibrodysplasia ossificans progressiva (FOP) to chromosome 17q21-22. Lucotte, G., Bathelier, C., Mercier, G., Gérard, N., Lenoir, G., Sémonin, O., Fontaine, K. Genetic counseling (Geneva, Switzerland) (2000) [Pubmed]
  27. Expression of bone morphogenetic proteins in colon carcinoma with heterotopic ossification. Imai, N., Iwai, A., Hatakeyama, S., Matsuzaki, K., Kitagawa, Y., Kato, S., Hokari, R., Kawaguchi, A., Nagao, S., Miyahara, T., Itoh, K., Miura, S. Pathol. Int. (2001) [Pubmed]
  28. Relation between ectopic ossification after total hip arthroplasty and activity of general inflammation in patients with ankylosing spondylitis. Tani, Y., Nishioka, J., Inoue, K., Hukuda, S., Tsujimoto, M. Ann. Rheum. Dis. (1998) [Pubmed]
  29. Prophylaxis with indomethacin for heterotopic ossification after Chiari osteotomy of the pelvis. Randelli, G., Romanò, C.L. The Journal of bone and joint surgery. American volume. (1992) [Pubmed]
  30. Naproxen in the prevention of heterotopic ossification after total hip replacement. Vielpeau, C., Joubert, J.M., Hulet, C. Clin. Orthop. Relat. Res. (1999) [Pubmed]
  31. Naproxen for 8 days can prevent heterotopic ossification after hip arthroplasty. Gebuhr, P., Wilbek, H., Soelberg, M. Clin. Orthop. Relat. Res. (1995) [Pubmed]
  32. The use of the three-phase bone scan in the early diagnosis of heterotopic ossification (HO) and in the evaluation of Didronel therapy. Freed, J.H., Hahn, H., Menter, R., Dillon, T. Paraplegia. (1982) [Pubmed]
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