Chemical Compound Review:
Sanzivamycin 5-amino-9-[(2R,3R,4S,5R)-3,4- dihydroxy-5...
Synonyms:
sangivamycin, CHEMBL101892, SureCN195540, CPD-13052, NSC-65346, ...
- Kinetic effects of sangivamycin in sarcoma 180 in vitro. Ritch, P.S., Glazer, R.I., Cunningham, R.E., Shackney, S.E. Cancer Res. (1981)
- Utilization of signal transduction pathway by the human T-cell leukemia virus type I transcriptional activator tax. Tan, T.H., Jia, R., Roeder, R.G. J. Virol. (1989)
- Design, synthesis and antiviral activity of novel 4,5-disubstituted 7-(beta-D-ribofuranosyl)pyrrolo[2,3-d][1,2,3]triazines and the novel 3-amino-5-methyl-1-(beta-D-ribofuranosyl)- and 3-amino-5-methyl-1-(2-deoxy-beta-D-ribofuranosyl)-1,5-dihydro-1,4,5,6,7,8-hexaazaacenaphthylene as analogues of triciribine. Migawa, M.T., Drach, J.C., Townsend, L.B. J. Med. Chem. (2005)
- Antagonism of the cytotoxic but not antiviral effects of ara-sangivamycin by adenosine. Birch, G.M., Krawczyk, S.H., Townsend, L.B., Drach, J.C. Antimicrob. Agents Chemother. (1989)
- Pyrrolopyrimidine nucleosides. 18. Synthesis and chemotherapeutic activity of 4-amino-7-(3-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d] pyrimidine-5-carboxamide (3'-deoxysangivamycin) and 4-amino-7-(2-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d] pyrimidine-5-carboxamide (2'-deoxysangivamycin). Maruyama, T., Wotring, L.L., Townsend, L.B. J. Med. Chem. (1983)
- Role of protein kinase C in parathyroid hormone stimulation of renal 1,25-dihydroxyvitamin D3 secretion. Janulis, M., Tembe, V., Favus, M.J. J. Clin. Invest. (1992)
- The influence of arrestin (48K protein) and rhodopsin kinase on visual transduction. Palczewski, K., Rispoli, G., Detwiler, P.B. Neuron (1992)
- c-myc is an erythropoietin early response gene in normal erythroid cells: evidence for a protein kinase C-mediated signal. Spangler, R., Sytkowski, A.J. Blood (1992)
- Kinetics and localization of the phosphorylation of rhodopsin by protein kinase C. Greene, N.M., Williams, D.S., Newton, A.C. J. Biol. Chem. (1995)
- Shape changes and chemokinesis of Walker carcinosarcoma cells: effects of protein kinase inhibitors (HA-1004, polymyxin B, sangivamycin and tamoxifen) and an inhibitor of diacylglycerol kinase (R 59022). Zimmermann, A., Keller, H. Anticancer Res. (1993)
- Sangivamycin, a nucleoside analogue, is a potent inhibitor of protein kinase C. Loomis, C.R., Bell, R.M. J. Biol. Chem. (1988)
- Regulation of prostaglandin endoperoxide synthase gene expression in cultured rat mesangial cells: induction by serum via a protein kinase-C-dependent mechanism. Simonson, M.S., Wolfe, J.A., Konieczkowski, M., Sedor, J.R., Dunn, M.J. Mol. Endocrinol. (1991)
- Comparison of the cellular and RNA-dependent effects of sangivamycin and toyocamycin in human colon carcinoma cells. Cohen, M.B., Glazer, R.I. Mol. Pharmacol. (1985)
- Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus. Turk, S.R., Shipman, C., Nassiri, R., Genzlinger, G., Krawczyk, S.H., Townsend, L.B., Drach, J.C. Antimicrob. Agents Chemother. (1987)
- Differential effects of pertussis toxin on insulin-stimulated phosphatidylcholine hydrolysis and glycerolipid synthesis de novo. Studies in BC3H-1 myocytes and rat adipocytes. Hoffman, J.M., Standaert, M.L., Nair, G.P., Farese, R.V. Biochemistry (1991)
- Egr-1 expression in surface Ig-mediated B cell activation. Kinetics and association with protein kinase C activation. Seyfert, V.L., McMahon, S., Glenn, W., Cao, X.M., Sukhatme, V.P., Monroe, J.G. J. Immunol. (1990)
- In vitro translational activity of messenger RNA following treatment of human colon carcinoma cells with sangivamycin. Glazer, R.I., Hartman, K.D. Mol. Pharmacol. (1983)
- Selective growth inhibition by sangivamycin of human umbilical vein endothelial cells. Ohno, O., Shima, Y., Ikeda, Y., Kondo, S.I., Kato, K., Toi, M., Umezawa, K. Int. J. Oncol. (2001)
- Phorbol myristate acetate induces ruffling of the acrosome of human sperm. Liu, d.e. .Y., Martic, M., Grkovic, I., Garrett, C., Dunlop, M.E., Baker, H.W. Fertil. Steril. (2002)
- Inhibition of protein kinases sensitizes human tumor cells to ionizing radiation. Hallahan, D.E., Virudachalam, S., Schwartz, J.L., Panje, N., Mustafi, R., Weichselbaum, R.R. Radiat. Res. (1992)
- Effect of protein kinase C inhibitors on the actions of phorbol esters on vascular tone and adrenergic transmission in the isolated rat kidney. Sehic, E., Malik, K.U. J. Pharmacol. Exp. Ther. (1990)
- X-ray crystal structure of sangivamycin, a potent inhibitor of protein kinases. Lebioda, L., Hargrave, P.A., Palczewski, K. FEBS Lett. (1990)
- Progesterone-stimulated intracellular calcium increase in human spermatozoa is protein kinase C-independent. Bonaccorsi, L., Krausz, C., Pecchioli, P., Forti, G., Baldi, E. Mol. Hum. Reprod. (1998)
- Platelet-activating factor enhances production of insulin-like growth factor binding proteins in a human adenocarcinoma cell line (HEC-1A). Giannini, S., Maggi, M., Cresci, B., Finetti, G., Bonaccorsi, L., Luconi, M., Rotella, C.M., Forti, G., Serio, M., Baldi, E. Gynecol. Oncol. (1996)
- Tumor promotion and depletion of protein kinase C in epidermal JB6 cells. Kischel, T., Harbers, M., Stabel, S., Borowski, P., Müller, K., Hilz, H. Biochem. Biophys. Res. Commun. (1989)
- Regulation of VCAM-1 expression and involvement in cell adhesion to murine microvascular endothelium. Bereta, J., Bereta, M., Cohen, S., Cohen, M.C. Cell. Immunol. (1993)
- Protein tyrosine kinase, mitogen-activated protein kinase and protein kinase C are involved in the mitogenic signaling of platelet-activating factor (PAF) in HEC-1A cells. Bonaccorsi, L., Luconi, M., Maggi, M., Muratori, M., Forti, G., Serio, M., Baldi, E. Biochim. Biophys. Acta (1997)
- The characteristics and pharmacology of olfactory cortical LTP induced by theta-burst high frequency stimulation and 1S,3R-ACPD. Collins, G.G. Neuropharmacology (1994)
- Antiviral activities of 2'-deoxyribofuranosyl and arabinofuranosyl analogs of sangivamycin against retro- and DNA viruses. Smee, D.F., McKernan, P.A., Alaghamandan, H.A., Frank, K.B., Ramasamy, K., Revankar, G.R., Robins, R.K. Antiviral Res. (1988)