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MeSH Review

Carcinosarcoma

 
 
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Disease relevance of Carcinosarcoma

 

High impact information on Carcinosarcoma

  • Response of Walker 256 carcinosarcoma cells to 12-O-tetradecanoylphorbol 13-acetate: possible regulation by endogenous cyclooxygenase metabolites [5].
  • Antitumor activity of a polychlorinated biphenyl mixture, Aroclor 1254, in rats inoculated with Walker 256 carcinosarcoma cells [6].
  • Rat Walker 256 (W256) carcinosarcoma cells express 12-LOX and synthesize 12(S)- and 15(S)-hydroxyeicosatetraenoic acids as their major LOX metabolites [7].
  • The present studies demonstrate that cleavage of C5a with trypsin generates a derivative peptide that is chemotactic for tumor cells (Walker carcinosarcoma) [8].
  • Walker 256/S carcinosarcoma causes osteoporosis-like changes through ectopical secretion of luteinizing hormone-releasing hormone [9].
 

Chemical compound and disease context of Carcinosarcoma

 

Biological context of Carcinosarcoma

 

Anatomical context of Carcinosarcoma

 

Gene context of Carcinosarcoma

 

Analytical, diagnostic and therapeutic context of Carcinosarcoma

References

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  6. Antitumor activity of a polychlorinated biphenyl mixture, Aroclor 1254, in rats inoculated with Walker 256 carcinosarcoma cells. Kerkvliet, N.I., Kimeldorf, D.J. J. Natl. Cancer Inst. (1977) [Pubmed]
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  8. Chemotactic factor for tumor cells derived from the C5a fragment of complement component C5. Orr, W., Phan, S.H., Varani, J., Ward, P.A., Kreutzer, D.L., Webster, R.O., Henson, P.M. Proc. Natl. Acad. Sci. U.S.A. (1979) [Pubmed]
  9. Walker 256/S carcinosarcoma causes osteoporosis-like changes through ectopical secretion of luteinizing hormone-releasing hormone. Waki, Y., Nomura, M., Kasugai, S., Ohya, K., Miyamoto, K. Cancer Res. (1999) [Pubmed]
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  19. Apoptosis of W256 carcinosarcoma cells of the monocytoid origin induced by NDGA involves lipid peroxidation and depletion of GSH: role of 12-lipoxygenase in regulating tumor cell survival. Tang, D.G., Honn, K.V. J. Cell. Physiol. (1997) [Pubmed]
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  22. O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts. Clemons, M., Kelly, J., Watson, A.J., Howell, A., McElhinney, R.S., McMurry, T.B., Margison, G.P. Br. J. Cancer (2005) [Pubmed]
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  29. The chemotactic response of tumor cells. A model for cancer metastasis. Lam, W.C., Delikatny, E.J., Orr, F.W., Wass, J., Varani, J., Ward, P.A. Am. J. Pathol. (1981) [Pubmed]
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