The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

provitamin-D3     (3S,9R,10R,13R,14R,17R)- 10,13-dimethyl-17...

Synonyms: Provitamin D3, SureCN3447, CHEMBL1797131, CHEBI:17759, D4429_SIGMA, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of C01164

 

High impact information on C01164

 

Chemical compound and disease context of C01164

 

Biological context of C01164

 

Anatomical context of C01164

 

Associations of C01164 with other chemical compounds

 

Gene context of C01164

 

Analytical, diagnostic and therapeutic context of C01164

References

  1. 7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome. Fitzky, B.U., Moebius, F.F., Asaoka, H., Waage-Baudet, H., Xu, L., Xu, G., Maeda, N., Kluckman, K., Hiller, S., Yu, H., Batta, A.K., Shefer, S., Chen, T., Salen, G., Sulik, K., Simoni, R.D., Ness, G.C., Glossmann, H., Patel, S.B., Tint, G.S. J. Clin. Invest. (2001) [Pubmed]
  2. Clothing prevents ultraviolet-B radiation-dependent photosynthesis of vitamin D3. Matsuoka, L.Y., Wortsman, J., Dannenberg, M.J., Hollis, B.W., Lu, Z., Holick, M.F. J. Clin. Endocrinol. Metab. (1992) [Pubmed]
  3. Vitamin D, its precursors, and metabolites do not affect melanization of cultured human melanocytes. Mansur, C.P., Gordon, P.R., Ray, S., Holick, M.F., Gilchrest, B.A. J. Invest. Dermatol. (1988) [Pubmed]
  4. Changes in serum sterols of rats treated with 7-dehydrocholesterol-delta 7-reductase inhibitors: comparison to levels in humans with Smith-Lemli-Opitz syndrome. Wolf, C., Chevy, F., Pham, J., Kolf-Clauw, M., Citadelle, D., Mulliez, N., Roux, C. J. Lipid Res. (1996) [Pubmed]
  5. Defective photoproduction of cholecalciferol in normal and uremic humans. Jacob, A.I., Sallman, A., Santiz, Z., Hollis, B.W. J. Nutr. (1984) [Pubmed]
  6. Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome. Tint, G.S., Irons, M., Elias, E.R., Batta, A.K., Frieden, R., Chen, T.S., Salen, G. N. Engl. J. Med. (1994) [Pubmed]
  7. Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin. MacLaughlin, J.A., Anderson, R.R., Holick, M.F. Science (1982) [Pubmed]
  8. Markedly inhibited 7-dehydrocholesterol-delta 7-reductase activity in liver microsomes from Smith-Lemli-Opitz homozygotes. Shefer, S., Salen, G., Batta, A.K., Honda, A., Tint, G.S., Irons, M., Elias, E.R., Chen, T.C., Holick, M.F. J. Clin. Invest. (1995) [Pubmed]
  9. Maternal urinary steroid profiles in prenatal diagnosis of Smith-Lemli-Opitz syndrome: first patient series comparing biochemical and molecular studies. Jezela-Stanek, A., Małunowicz, E.M., Ciara, E., Popowska, E., Goryluk-Kozakiewicz, B., Spodar, K., Czerwiecka, M., Jezuita, J., Nowaczyk, M.J., Krajewska-Walasek, M. Clin. Genet. (2006) [Pubmed]
  10. Fetal demise with Smith-Lemli-Opitz syndrome confirmed by tissue sterol analysis and the absence of measurable 7-dehydrocholesterol Delta(7)-reductase activity in chorionic villi. Linck, L.M., Hayflick, S.J., Lin, D.S., Battaile, K.P., Ginat, S., Burlingame, T., Gibson, K.M., Honda, M., Honda, A., Salen, G., Tint, G.S., Connor, W.E., Steiner, R.D. Prenat. Diagn. (2000) [Pubmed]
  11. Effect of various vitamin D analogs on plasma calcium and phosphorus and intestinal calcium absorption in fed and unfed American eels, Anguilla rostrata. Fenwick, J.C., Smith, K., Smith, J., Flik, G. Gen. Comp. Endocrinol. (1984) [Pubmed]
  12. Prenatal diagnosis of Smith-Lemli-Opitz syndrome in a pregnancy with low maternal serum oestriol and a sex-reversed fetus. Bick, D.P., McCorkle, D., Stanley, W.S., Stern, H.J., Staszak, P., Berkovitz, G.D., Meyers, C.M., Kelley, R.I. Prenat. Diagn. (1999) [Pubmed]
  13. Neverland is an evolutionally conserved Rieske-domain protein that is essential for ecdysone synthesis and insect growth. Yoshiyama, T., Namiki, T., Mita, K., Kataoka, H., Niwa, R. Development (2006) [Pubmed]
  14. Ultraviolet A induces apoptosis via reactive oxygen species in a model for Smith-Lemli-Opitz syndrome. Valencia, A., Kochevar, I.E. Free Radic. Biol. Med. (2006) [Pubmed]
  15. 7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemli-Opitz syndrome skin fibroblasts. Honda, M., Tint, G.S., Honda, A., Nguyen, L.B., Chen, T.S., Shefer, S. J. Lipid Res. (1998) [Pubmed]
  16. Kinetic and thermodynamic studies of the conversion of previtamin D3 to vitamin D3 in human skin. Tian, X.Q., Chen, T.C., Matsuoka, L.Y., Wortsman, J., Holick, M.F. J. Biol. Chem. (1993) [Pubmed]
  17. Equine type estrogens produced by a pregnant woman carrying a Smith-Lemli-Opitz syndrome fetus. Shackleton, C.H., Roitman, E., Kratz, L.E., Kelley, R.I. J. Clin. Endocrinol. Metab. (1999) [Pubmed]
  18. 7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: Roles of NADPH oxidase, mitochondria, and lipid rafts. Valencia, A., Rajadurai, A., Carle, A.B., Kochevar, I.E. Free Radic. Biol. Med. (2006) [Pubmed]
  19. Silver ion high pressure liquid chromatography provides unprecedented separation of sterols: application to the enzymatic formation of cholesta-5,8-dien-3 beta-ol. Ruan, B., Shey, J., Gerst, N., Wilson, W.K., Schroepfer, G.J. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  20. Blocking late cholesterol biosynthesis inhibits the growth of transplanted Morris hepatomas (7288CTC) in rats. Xu, G., Salen, G., Lea, M., Tint, G.S., Nguyen, L.B., Batta, A.K., Chen, T.S., Shefer, S. Hepatology (1996) [Pubmed]
  21. Isolation and identification of 24-dehydroprovitamin D3 and its photolysis to 24-dehydroprevitamin D3 in mammalian skin. Holick, S.A., Lezin, M.S., Young, D., Malaikal, S., Holick, M.F. J. Biol. Chem. (1985) [Pubmed]
  22. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Holick, M.F. Am. J. Clin. Nutr. (2004) [Pubmed]
  23. A pathway for the metabolism of vitamin D3: unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1). Guryev, O., Carvalho, R.A., Usanov, S., Gilep, A., Estabrook, R.W. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  24. Sterol carrier protein X is peroxisomal 3-oxoacyl coenzyme A thiolase with intrinsic sterol carrier and lipid transfer activity. Seedorf, U., Brysch, P., Engel, T., Schrage, K., Assmann, G. J. Biol. Chem. (1994) [Pubmed]
  25. Molecular cloning and structural analysis of human sterol C5 desaturase. Sugawara, T., Fujimoto, Y., Ishibashi, T. Biochim. Biophys. Acta (2001) [Pubmed]
  26. Structure and alternative splicing of the rat 7-dehydrocholesterol reductase gene. Lee, J.N., Bae, S.H., Paik, Y.K. Biochim. Biophys. Acta (2002) [Pubmed]
  27. RPR 101821, a new potent cholesterol-lowering agent: inhibition of squalene synthase and 7-dehydrocholesterol reductase. Amin, D., Rutledge, R.Z., Needle, S.J., Hele, D.J., Neuenswander, K., Bush, R.C., Bilder, G.E., Perrone, M.H. Naunyn Schmiedebergs Arch. Pharmacol. (1996) [Pubmed]
  28. Smith-Lemli-Opitz syndrome diagnosed by using time-of-flight secondary-ion mass spectrometry. Seedorf, U., Fobker, M., Voss, R., Meyer, K., Kannenberg, F., Meschede, D., Ullrich, K., Horst, J., Benninghoven, A., Assmann, G. Clin. Chem. (1995) [Pubmed]
  29. First trimester prenatal diagnosis of Smith-Lemli-Opitz syndrome (7-dehydrocholesterol reductase deficiency). Mills, K., Mandel, H., Montemagno, R., Soothill, P., Gershoni-Baruch, R., Clayton, P.T. Pediatr. Res. (1996) [Pubmed]
 
WikiGenes - Universities