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Chemical Compound Review

Fungizone     (1R,3S,5R,6R,9R,11R,15S,16R,17 R,18S,19E...

Synonyms: Abelecet, Ambisome, Amphocin, Amphotec, Fungilin, ...
 
 
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Disease relevance of Tegopen

 

High impact information on Tegopen

 

Chemical compound and disease context of Tegopen

 

Biological context of Tegopen

 

Anatomical context of Tegopen

 

Associations of Tegopen with other chemical compounds

 

Gene context of Tegopen

  • Liposomal amphotericin B activates antifungal resistance with reduced toxicity by diverting Toll-like receptor signalling from TLR-2 to TLR-4 [30].
  • Fungizone (FZ) and Amphotec (ABCD) caused the release of significantly more inflammatory molecules and the release of inflammatory molecules at higher levels than either AmBisome (L-AMB) or Abelcet (ABLC) after 6 h of treatment [31].
  • The role of IFN-gamma is selective, since it is not a cofactor in the response to AmB [32].
  • Treatment with either Sb or AmB permits an iNOS-independent mechanism to emerge and control residual intracellular L. donovani infection [32].
  • Treatment with AmB, SP-D, and rSP-D increased the survival rate to 80, 60, and 80%, respectively, suggesting that SP-D (and rSP-D) can protect immunosuppressed mice from an otherwise fatal challenge with Aspergillus fumigatus conidia [33].
 

Analytical, diagnostic and therapeutic context of Tegopen

References

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