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Granulomatous Disease, Chronic

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Gene context of Granulomatous Disease, Chronic


Analytical, diagnostic and therapeutic context of Granulomatous Disease, Chronic


  1. Viricidal effect of polymorphonuclear leukocytes on human immunodeficiency virus-1. Role of the myeloperoxidase system. Klebanoff, S.J., Coombs, R.W. J. Clin. Invest. (1992) [Pubmed]
  2. Enhanced bactericidal activity of phagocytes from patients with chronic granulomatous disease in the presence of sulphisoxazole. Johnston, R.B., Wilfert, C.M., Buckley, R.H., Webb, L.S., DcChatelet, L.R., McCall, C.E. Lancet (1975) [Pubmed]
  3. Minor Xp21 chromosome deletion in a male associated with expression of Duchenne muscular dystrophy, chronic granulomatous disease, retinitis pigmentosa, and McLeod syndrome. Francke, U., Ochs, H.D., de Martinville, B., Giacalone, J., Lindgren, V., Distèche, C., Pagon, R.A., Hofker, M.H., van Ommen, G.J., Pearson, P.L. Am. J. Hum. Genet. (1985) [Pubmed]
  4. Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox. Zhen, L., King, A.A., Xiao, Y., Chanock, S.J., Orkin, S.H., Dinauer, M.C. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  5. Viricidal effect of stimulated human mononuclear phagocytes on human immunodeficiency virus type 1. Chase, M.J., Klebanoff, S.J. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  6. Treatment of chronic granulomatous disease with nonmyeloablative conditioning and a T-cell-depleted hematopoietic allograft. Horwitz, M.E., Barrett, A.J., Brown, M.R., Carter, C.S., Childs, R., Gallin, J.I., Holland, S.M., Linton, G.F., Miller, J.A., Leitman, S.F., Read, E.J., Malech, H.L. N. Engl. J. Med. (2001) [Pubmed]
  7. Genetic variants of chronic granulomatous disease: prevalence of deficiencies of two cytosolic components of the NADPH oxidase system. Clark, R.A., Malech, H.L., Gallin, J.I., Nunoi, H., Volpp, B.D., Pearson, D.W., Nauseef, W.M., Curnutte, J.T. N. Engl. J. Med. (1989) [Pubmed]
  8. A variant of chronic granulomatous disease: deficient oxidative metabolism due to a low-affinity NADPH oxidase. Lew, P.D., Southwick, F.S., Stossel, T.P., Whitin, J.C., Simons, E., Cohen, H.J. N. Engl. J. Med. (1981) [Pubmed]
  9. Defect in pyridine nucleotide dependent superoxide production by a particulate fraction from the cranulocytes of patients with chronic granulomatous disease. Curnutte, J.T., Kipnes, R.S., Babior, B.M. N. Engl. J. Med. (1975) [Pubmed]
  10. The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex. Dinauer, M.C., Orkin, S.H., Brown, R., Jesaitis, A.J., Parkos, C.A. Nature (1987) [Pubmed]
  11. Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src. Leto, T.L., Lomax, K.J., Volpp, B.D., Nunoi, H., Sechler, J.M., Nauseef, W.M., Clark, R.A., Gallin, J.I., Malech, H.L. Science (1990) [Pubmed]
  12. The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate. Bravo, J., Karathanassis, D., Pacold, C.M., Pacold, M.E., Ellson, C.D., Anderson, K.E., Butler, P.J., Lavenir, I., Perisic, O., Hawkins, P.T., Stephens, L., Williams, R.L. Mol. Cell (2001) [Pubmed]
  13. Oxidative degradation of leukotriene C4 by human monocytes and monocyte-derived macrophages. Neill, M.A., Henderson, W.R., Klebanoff, S.J. J. Exp. Med. (1985) [Pubmed]
  14. The particulate superoxide-forming system from human neutrophils. Properties of the system and further evidence supporting its participation in the respiratory burst. Babior, B.M., Curnutte, J.T., McMurrich, B.J. J. Clin. Invest. (1976) [Pubmed]
  15. Evidence for hydroxyl radical production by human neutrophils. Tauber, A.I., Babior, B.M. J. Clin. Invest. (1977) [Pubmed]
  16. A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease. Görlach, A., Lee, P.L., Roesler, J., Hopkins, P.J., Christensen, B., Green, E.D., Chanock, S.J., Curnutte, J.T. J. Clin. Invest. (1997) [Pubmed]
  17. Evidence for hydroxyl radical generation by human Monocytes. Weiss, S.J., King, G.W., LoBuglio, A.F. J. Clin. Invest. (1977) [Pubmed]
  18. Protein phosphorylation in neutrophils from patients with p67-phox-deficient chronic granulomatous disease. Heyworth, P.G., Ding, J., Erickson, R.W., Lu, D.J., Curnutte, J.T., Badwey, J.A. Blood (1996) [Pubmed]
  19. Pyridine nucleotide-dependent superoxide production by a cell-free system from human granulocytes. Babior, B.M., Curnutte, J.T., Kipnes, B.S. J. Clin. Invest. (1975) [Pubmed]
  20. In vitro molecular reconstitution of the respiratory burst in B lymphoblasts from p47-phox-deficient chronic granulomatous disease. Volpp, B.D., Lin, Y. J. Clin. Invest. (1993) [Pubmed]
  21. Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system. Curnutte, J.T. J. Clin. Invest. (1985) [Pubmed]
  22. Fibroblast nitroblue tetrazolium test and the in-utero diagnosis of chronic granulomatous disease. Fikrig, S.M., Smithwick, E.M., Suntharalingam, K., Good, R.A. Lancet (1980) [Pubmed]
  23. Involvement of p40phox in activation of phagocyte NADPH oxidase through association of its carboxyl-terminal, but not its amino-terminal, with p67phox. Tsunawaki, S., Kagara, S., Yoshikawa, K., Yoshida, L.S., Kuratsuji, T., Namiki, H. J. Exp. Med. (1996) [Pubmed]
  24. Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease. Dinauer, M.C., Pierce, E.A., Bruns, G.A., Curnutte, J.T., Orkin, S.H. J. Clin. Invest. (1990) [Pubmed]
  25. X-Linked chronic granulomatous disease: mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase. Rae, J., Newburger, P.E., Dinauer, M.C., Noack, D., Hopkins, P.J., Kuruto, R., Curnutte, J.T. Am. J. Hum. Genet. (1998) [Pubmed]
  26. Genes for two autosomal recessive forms of chronic granulomatous disease assigned to 1q25 (NCF2) and 7q11.23 (NCF1). Francke, U., Hsieh, C.L., Foellmer, B.E., Lomax, K.J., Malech, H.L., Leto, T.L. Am. J. Hum. Genet. (1990) [Pubmed]
  27. O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase. Archer, S.L., Reeve, H.L., Michelakis, E., Puttagunta, L., Waite, R., Nelson, D.P., Dinauer, M.C., Weir, E.K. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  28. Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease. Malech, H.L., Maples, P.B., Whiting-Theobald, N., Linton, G.F., Sekhsaria, S., Vowells, S.J., Li, F., Miller, J.A., DeCarlo, E., Holland, S.M., Leitman, S.F., Carter, C.S., Butz, R.E., Read, E.J., Fleisher, T.A., Schneiderman, R.D., Van Epps, D.E., Spratt, S.K., Maack, C.A., Rokovich, J.A., Cohen, L.K., Gallin, J.I. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  29. Characterization of the p67phox gene: genomic organization and restriction fragment length polymorphism analysis for prenatal diagnosis in chronic granulomatous disease. Kenney, R.T., Malech, H.L., Epstein, N.D., Roberts, R.L., Leto, T.L. Blood (1993) [Pubmed]
  30. Cytochrome b-245 of the neutrophil superoxide-generating system contains two nonidentical hemes. Potentiometric studies of a mutant form of gp91phox. Cross, A.R., Rae, J., Curnutte, J.T. J. Biol. Chem. (1995) [Pubmed]
  31. Current approaches to diagnosis and treatment of invasive aspergillosis. Segal, B.H., Walsh, T.J. Am. J. Respir. Crit. Care Med. (2006) [Pubmed]
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