Gene Review:
Atp7b - ATPase, Cu++ transporting, beta polypeptide
Mus musculus
Synonyms:
Atp7a, Copper pump 2, Copper-transporting ATPase 2, WND, Wilson disease-associated protein homolog, ...
- Effect of the toxic milk mutation (tx) on the function and intracellular localization of Wnd, the murine homologue of the Wilson copper ATPase. La Fontaine , S., Theophilos, M.B., Firth, S.D., Gould, R., Parton, R.G., Mercer, J.F. Hum. Mol. Genet. (2001)
- The copper-transporting ATPases, menkes and wilson disease proteins, have distinct roles in adult and developing cerebellum. Barnes, N., Tsivkovskii, R., Tsivkovskaia, N., Lutsenko, S. J. Biol. Chem. (2005)
- Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo. Sheline, C.T., Choi, D.W. Ann. Neurol. (2004)
- Null mutation of the murine ATP7B (Wilson disease) gene results in intracellular copper accumulation and late-onset hepatic nodular transformation. Buiakova, O.I., Xu, J., Lutsenko, S., Zeitlin, S., Das, K., Das, S., Ross, B.M., Mekios, C., Scheinberg, I.H., Gilliam, T.C. Hum. Mol. Genet. (1999)
- Retinal localization and copper-dependent relocalization of the Wilson and Menkes disease proteins. Krajacic, P., Qian, Y., Hahn, P., Dentchev, T., Lukinova, N., Dunaief, J.L. Invest. Ophthalmol. Vis. Sci. (2006)
- Foreward:alpha-melanocyte stimulating hormone and the melanocortin receptors. Taylor, A. Cell. Mol. Biol. (Noisy-le-grand) (2006)
- Deletion of the promoter region in the Atp7a gene of the mottled dappled mouse. Levinson, B., Packman, S., Gitschier, J. Nat. Genet. (1997)
- The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene. Wu, J., Forbes, J.R., Chen, H.S., Cox, D.W. Nat. Genet. (1994)
- Epstein-Barr virus (EBV)-associated lymphoproliferative disease in the SCID mouse model: implications for the pathogenesis of EBV-positive lymphomas in man. Rowe, M., Young, L.S., Crocker, J., Stokes, H., Henderson, S., Rickinson, A.B. J. Exp. Med. (1991)
- Murine t factors: an association between alleles at t and at H-2. Levinson, J.R., McDevitt, H.O. J. Exp. Med. (1976)
- Copper efflux from murine microvascular cells requires expression of the menkes disease Cu-ATPase. Qian, Y., Tiffany-Castiglioni, E., Welsh, J., Harris, E.D. J. Nutr. (1998)
- Functional expression of the Wilson disease protein reveals mislocalization and impaired copper-dependent trafficking of the common H1069Q mutation. Payne, A.S., Kelly, E.J., Gitlin, J.D. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Consequences of copper accumulation in the livers of the Atp7b-/- (Wilson disease gene) knockout mice. Huster, D., Finegold, M.J., Morgan, C.T., Burkhead, J.L., Nixon, R., Vanderwerf, S.M., Gilliam, C.T., Lutsenko, S. Am. J. Pathol. (2006)
- Mapping of the mouse homologue of the Wilson disease gene to mouse chromosome 8. Reed, V., Williamson, P., Bull, P.C., Cox, D.W., Boyd, Y. Genomics (1995)
- Essential roles in development and pigmentation for the Drosophila copper transporter DmATP7. Norgate, M., Lee, E., Southon, A., Farlow, A., Batterham, P., Camakaris, J., Burke, R. Mol. Biol. Cell (2006)
- Expression in mouse kidney of membrane copper transporters Atp7a and Atp7b. Moore, S.D., Cox, D.W. Nephron (2002)
- The toxic milk mouse is a murine model of Wilson disease. Theophilos, M.B., Cox, D.W., Mercer, J.F. Hum. Mol. Genet. (1996)
- Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity. Schlief, M.L., West, T., Craig, A.M., Holtzman, D.M., Gitlin, J.D. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Glycosylation-dependent inactivation of the ecotropic murine leukemia virus receptor. Eiden, M.V., Farrell, K., Wilson, C.A. J. Virol. (1994)
- Catalytic mechanism of yeast adenosine 5'-monophosphate deaminase. Zinc content, substrate specificity, pH studies, and solvent isotope effects. Merkler, D.J., Schramm, V.L. Biochemistry (1993)
- Reduction of copper and metallothionein in toxic milk mice by tetrathiomolybdate, but not deferiprone. Czachor, J.D., Cherian, M.G., Koropatnick, J. J. Inorg. Biochem. (2002)
- Decreased carbonic anhydrase III levels in the liver of the mouse mutant 'toxic milk' (tx) due to copper accumulation. Grimes, A., Paynter, J., Walker, I.D., Bhave, M., Mercer, J.F. Biochem. J. (1997)
- Regional brain distribution of metallothionein, zinc and copper in toxic milk mutant and transgenic mice. Ono, S., Koropatnick, D.J., Cherian, M.G. Toxicology (1997)
- Defective localization of the Wilson disease protein (ATP7B) in the mammary gland of the toxic milk mouse and the effects of copper supplementation. Michalczyk, A.A., Rieger, J., Allen, K.J., Mercer, J.F., Ackland, M.L. Biochem. J. (2000)