Gene Review:
Grin2a - glutamate receptor, ionotropic, NMDA2A...
Mus musculus
Synonyms:
GluN2A, GluRepsilon1, Glutamate receptor ionotropic, NMDA 2A, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, ...
- Attenuation of focal ischemic brain injury in mice deficient in the epsilon1 (NR2A) subunit of NMDA receptor. Morikawa, E., Mori, H., Kiyama, Y., Mishina, M., Asano, T., Kirino, T. J. Neurosci. (1998)
- Immunity and behavior: antibodies alter emotion. Huerta, P.T., Kowal, C., DeGiorgio, L.A., Volpe, B.T., Diamond, B. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Characterization of N-methyl-D-aspartate receptor subunits responsible for postoperative pain. Nishimura, W., Muratani, T., Tatsumi, S., Sakimura, K., Mishina, M., Minami, T., Ito, S. Eur. J. Pharmacol. (2004)
- Roles of diverse glutamate receptors in brain functions elucidated by subunit-specific and region-specific gene targeting. Mori, H., Mishina, M. Life Sci. (2003)
- Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition. Lu, H.C., Gonzalez, E., Crair, M.C. Neuron (2001)
- Genetic Inactivation of the NMDA Receptor NR2A Subunit has Anxiolytic- and Antidepressant-Like Effects in Mice. Boyce-Rustay, J.M., Holmes, A. Neuropsychopharmacology (2006)
- Behavioural adaptations to addictive drugs in mice lacking the NMDA receptor epsilon1 subunit. Miyamoto, Y., Yamada, K., Nagai, T., Mori, H., Mishina, M., Furukawa, H., Noda, Y., Nabeshima, T. Eur. J. Neurosci. (2004)
- Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory. Zhao, M.G., Toyoda, H., Lee, Y.S., Wu, L.J., Ko, S.W., Zhang, X.H., Jia, Y., Shum, F., Xu, H., Li, B.M., Kaang, B.K., Zhuo, M. Neuron (2005)
- Do NMDA receptor kinetics regulate the end of critical periods of plasticity? Medina, A.E., Liao, D.S., Mower, A.F., Ramoa, A.S. Neuron (2001)
- Developmental loss of miniature N-methyl-D-aspartate receptor currents in NR2A knockout mice. Townsend, M., Yoshii, A., Mishina, M., Constantine-Paton, M. Proc. Natl. Acad. Sci. U.S.A. (2003)
- High-affinity zinc inhibition of NMDA NR1-NR2A receptors. Paoletti, P., Ascher, P., Neyton, J. J. Neurosci. (1997)
- Long-term NR2B expression in the cerebellum alters granule cell development and leads to NR2A down-regulation and motor deficits. Schlett, K., Pieri, I., Metzger, F., Marchetti, L., Steigerwald, F., Dere, E., Kirilly, D., Tárnok, K., Barabás, B., Varga, A.K., Gerspach, J., Huston, J., Pfizenmaier, K., Köhr, G., Eisel, U.L. Mol. Cell. Neurosci. (2004)
- Reduced NMDA receptor tyrosine phosphorylation in PTPalpha-deficient mouse synaptosomes is accompanied by inhibition of four src family kinases and Pyk2: an upstream role for PTPalpha in NMDA receptor regulation. Le, H.T., Maksumova, L., Wang, J., Pallen, C.J. J. Neurochem. (2006)
- Unaltered pain-related behavior in mice lacking NMDA receptor GluRepsilon 1 subunit. Petrenko, A.B., Yamakura, T., Baba, H., Sakimura, K. Neurosci. Res. (2003)
- Input-specific targeting of NMDA receptor subtypes at mouse hippocampal CA3 pyramidal neuron synapses. Ito, I., Kawakami, R., Sakimura, K., Mishina, M., Sugiyama, H. Neuropharmacology (2000)
- Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain. Abe, T., Matsumura, S., Katano, T., Mabuchi, T., Takagi, K., Xu, L., Yamamoto, A., Hattori, K., Yagi, T., Watanabe, M., Nakazawa, T., Yamamoto, T., Mishina, M., Nakai, Y., Ito, S. Eur. J. Neurosci. (2005)
- NMDA receptor subunits GluRepsilon1, GluRepsilon3 and GluRzeta1 are enriched at the mossy fibre-granule cell synapse in the adult mouse cerebellum. Yamada, K., Fukaya, M., Shimizu, H., Sakimura, K., Watanabe, M. Eur. J. Neurosci. (2001)
- Regulated appearance of NMDA receptor subunits and channel functions during in vitro neuronal differentiation. Jelitai, M., Schlett, K., Varju, P., Eisel, U., Madarász, E. J. Neurobiol. (2002)
- Ethanol-related behaviors in mice lacking the NMDA receptor NR2A subunit. Boyce-Rustay, J.M., Holmes, A. Psychopharmacology (Berl.) (2006)
- Characterization of N-methyl-D-aspartate receptor subunits involved in acute ammonia toxicity. Kitano, T., Matsumura, S., Seki, T., Hikida, T., Sakimura, K., Nagano, T., Mishina, M., Nakanishi, S., Ito, S. Neurochem. Int. (2004)
- Identification of PSD-93 as a substrate for the Src family tyrosine kinase Fyn. Nada, S., Shima, T., Yanai, H., Husi, H., Grant, S.G., Okada, M., Akiyama, T. J. Biol. Chem. (2003)
- NR2A but not NR2B N-methyl-D-aspartate receptor subunit is altered in the visual cortex of BDNF-knock-out mice. Margottil, E., Domenici, L. Cell. Mol. Neurobiol. (2003)
- NR2A induction and NMDA receptor-dependent neuronal death by neurotrophin-4/5 in cortical cell culture. Choi, S.Y., Hwang, J.J., Koh, J.Y. J. Neurochem. (2004)
- Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression. Li, S., Tian, X., Hartley, D.M., Feig, L.A. J. Neurosci. (2006)
- Schedule of NMDA receptor subunit expression and functional channel formation in the course of in vitro-induced neurogenesis. Varju, P., Schlett, K., Eisel, U., Madarász, E. J. Neurochem. (2001)
- Selective scarcity of NMDA receptor channel subunits in the stratum lucidum (mossy fibre-recipient layer) of the mouse hippocampal CA3 subfield. Watanabe, M., Fukaya, M., Sakimura, K., Manabe, T., Mishina, M., Inoue, Y. Eur. J. Neurosci. (1998)
- Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunit. Miyamoto, Y., Yamada, K., Noda, Y., Mori, H., Mishina, M., Nabeshima, T. J. Neurosci. (2001)
- Deletion of the NR2A subunit prevents developmental changes of NMDA-mEPSCs in cultured mouse cerebellar granule neurones. Fu, Z., Logan, S.M., Vicini, S. J. Physiol. (Lond.) (2005)