Gene Review:
Nog - noggin
Mus musculus
Synonyms:
Noggin
Sugi,
Yamamura,
Okagawa,
Markwald,
Allen,
Bogardi,
Barlow,
Mir,
Qayyum,
Verbeek,
Anderson,
Francis-West,
Brown,
Richardson,
Miyazaki,
Ueda,
Yokoo,
Utsunomiya,
Kawamura,
Matsusaka,
Ichikawa,
Hosoya,
Botchkarev,
Botchkareva,
Sharov,
Funa,
Huber,
Gilchrest,
Chalazonitis,
D'Autréaux,
Guha,
Pham,
Faure,
Chen,
Roman,
Kan,
Rothman,
Kessler,
Gershon,
Botchkarev,
Botchkareva,
Nakamura,
Huber,
Funa,
Lauster,
Paus,
Gilchrest,
- Modulation of BMP signaling by noggin is required for induction of the secondary (nontylotrich) hair follicles. Botchkarev, V.A., Botchkareva, N.V., Sharov, A.A., Funa, K., Huber, O., Gilchrest, B.A. J. Invest. Dermatol. (2002)
- The BMP antagonist noggin regulates cranial suture fusion. Warren, S.M., Brunet, L.J., Harland, R.M., Economides, A.N., Longaker, M.T. Nature (2003)
- Noggin and sclerostin bone morphogenetic protein antagonists form a mutually inhibitory complex. Winkler, D.G., Yu, C., Geoghegan, J.C., Ojala, E.W., Skonier, J.E., Shpektor, D., Sutherland, M.K., Latham, J.A. J. Biol. Chem. (2004)
- Misexpression of noggin leads to septal defects in the outflow tract of the chick heart. Allen, S.P., Bogardi, J.P., Barlow, A.J., Mir, S.A., Qayyum, S.R., Verbeek, F.J., Anderson, R.H., Francis-West, P.H., Brown, N.A., Richardson, M.K. Dev. Biol. (2001)
- Function of BMPs in the apical ectoderm of the developing mouse limb. Wang, C.K., Omi, M., Ferrari, D., Cheng, H.C., Lizarraga, G., Chin, H.J., Upholt, W.B., Dealy, C.N., Kosher, R.A. Dev. Biol. (2004)
- Heterozygous mutations in the gene encoding noggin affect human joint morphogenesis. Gong, Y., Krakow, D., Marcelino, J., Wilkin, D., Chitayat, D., Babul-Hirji, R., Hudgins, L., Cremers, C.W., Cremers, F.P., Brunner, H.G., Reinker, K., Rimoin, D.L., Cohn, D.H., Goodman, F.R., Reardon, W., Patton, M., Francomano, C.A., Warman, M.L. Nat. Genet. (1999)
- The organizer factors Chordin and Noggin are required for mouse forebrain development. Bachiller, D., Klingensmith, J., Kemp, C., Belo, J.A., Anderson, R.M., May, S.R., McMahon, J.A., McMahon, A.P., Harland, R.M., Rossant, J., De Robertis, E.M. Nature (2000)
- Dkk1 and noggin cooperate in mammalian head induction. del Barco Barrantes, I., Davidson, G., Gröne, H.J., Westphal, H., Niehrs, C. Genes Dev. (2003)
- Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice. Wu, X.B., Li, Y., Schneider, A., Yu, W., Rajendren, G., Iqbal, J., Yamamoto, M., Alam, M., Brunet, L.J., Blair, H.C., Zaidi, M., Abe, E. J. Clin. Invest. (2003)
- Noggin gene delivery inhibits cementoblast-induced mineralization. Jin, Q.M., Zhao, M., Economides, A.N., Somerman, M.J., Giannobile, W.V. Connect. Tissue Res. (2004)
- Chordin and noggin promote organizing centers of forebrain development in the mouse. Anderson, R.M., Lawrence, A.R., Stottmann, R.W., Bachiller, D., Klingensmith, J. Development (2002)
- Embryonic signaling centers expressing BMP, WNT and FGF proteins interact to pattern the cerebral cortex. Shimogori, T., Banuchi, V., Ng, H.Y., Strauss, J.B., Grove, E.A. Development (2004)
- The BMP antagonists Chordin and Noggin have essential but redundant roles in mouse mandibular outgrowth. Stottmann, R.W., Anderson, R.M., Klingensmith, J. Dev. Biol. (2001)
- Noggin is required for induction of the hair follicle growth phase in postnatal skin. Botchkarev, V.A., Botchkareva, N.V., Nakamura, M., Huber, O., Funa, K., Lauster, R., Paus, R., Gilchrest, B.A. FASEB J. (2001)
- Bone morphogenetic protein signals are required for cartilage formation and differently regulate joint development during skeletogenesis. Tsumaki, N., Nakase, T., Miyaji, T., Kakiuchi, M., Kimura, T., Ochi, T., Yoshikawa, H. J. Bone Miner. Res. (2002)
- Opposing effects of bone morphogenetic proteins on neuron production and survival in the olfactory receptor neuron lineage. Shou, J., Murray, R.C., Rim, P.C., Calof, A.L. Development (2000)
- Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus. Matsumoto, H., Zhao, X., Das, S.K., Hogan, B.L., Dey, S.K. Dev. Biol. (2002)
- Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice. Sugi, Y., Yamamura, H., Okagawa, H., Markwald, R.R. Dev. Biol. (2004)
- Noggin expression in a mesodermal pluripotent cell line C1 and its regulation by BMP. Nifuji, A., Kellermann, O., Noda, M. J. Cell. Biochem. (1999)
- Inhibition of endogenous BMP in the glomerulus leads to mesangial matrix expansion. Miyazaki, Y., Ueda, H., Yokoo, T., Utsunomiya, Y., Kawamura, T., Matsusaka, T., Ichikawa, I., Hosoya, T. Biochem. Biophys. Res. Commun. (2006)
- Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation. Miriyala, S., Gongora Nieto, M.C., Mingone, C., Smith, D., Dikalov, S., Harrison, D.G., Jo, H. Circulation (2006)
- Bone morphogenetic protein-2 and -4 limit the number of enteric neurons but promote development of a TrkC-expressing neurotrophin-3-dependent subset. Chalazonitis, A., D'Autréaux, F., Guha, U., Pham, T.D., Faure, C., Chen, J.J., Roman, D., Kan, L., Rothman, T.P., Kessler, J.A., Gershon, M.D. J. Neurosci. (2004)
- Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development. Okamoto, M., Murai, J., Yoshikawa, H., Tsumaki, N. J. Bone Miner. Res. (2006)
- FGF18 represses noggin expression and is induced by calcineurin. Reinhold, M.I., Abe, M., Kapadia, R.M., Liao, Z., Naski, M.C. J. Biol. Chem. (2004)
- The BMP antagonists cerberus-like and noggin do not interact during mouse forebrain development. Borges, A.C., Marques, S., Belo, J.A. Int. J. Dev. Biol. (2001)
- HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins. Oka, C., Tsujimoto, R., Kajikawa, M., Koshiba-Takeuchi, K., Ina, J., Yano, M., Tsuchiya, A., Ueta, Y., Soma, A., Kanda, H., Matsumoto, M., Kawaichi, M. Development (2004)
- Stage specific inhibition of osteoblast lineage differentiation by FGF2 and noggin. Kalajzic, I., Kalajzic, Z., Hurley, M.M., Lichtler, A.C., Rowe, D.W. J. Cell. Biochem. (2003)
- Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors. Paria, B.C., Ma, W., Tan, J., Raja, S., Das, S.K., Dey, S.K., Hogan, B.L. Proc. Natl. Acad. Sci. U.S.A. (2001)
- BMP4 promotes chondrocyte proliferation and hypertrophy in the endochondral cranial base. Shum, L., Wang, X., Kane, A.A., Nuckolls, G.H. Int. J. Dev. Biol. (2003)
- Coordinated expression of noggin and bone morphogenetic proteins (BMPs) during early skeletogenesis and induction of noggin expression by BMP-7. Nifuji, A., Noda, M. J. Bone Miner. Res. (1999)