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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Brain Diseases

 
 
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Disease relevance of Brain Diseases

 

Psychiatry related information on Brain Diseases

 

High impact information on Brain Diseases

  • Heterozygous mutation or deletion of the beta subunit of platelet-activating factor acetylhydrolase (PAFAH1B1, also known as LIS1) in humans is associated with type I lissencephaly, a severe developmental brain disorder thought to result from abnormal neuronal migration [11].
  • Deficiency of guanine deaminase in human brain: a new brain disorder [12]?
  • The HAP-1 protein is enriched in the brain, suggesting a possible basis for the selective brain pathology of HD [13].
  • The functional interaction between these corticosteroid-responsive inputs at the level of the PVN is probably the key to understanding HPA dysregulation associated with stress-related brain disorders [14].
  • Dopamine beta-hydroxylase activity may delineate a subgroup of patients who have a dopamine-sensitive brain disorder [15].
 

Chemical compound and disease context of Brain Diseases

 

Biological context of Brain Diseases

 

Anatomical context of Brain Diseases

 

Gene context of Brain Diseases

  • Furthermore, the current knowledge about drug efflux transporters as a major determinant of multidrug resistance of brain diseases such as epilepsy is reviewed [31].
  • Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases [32].
  • As OSM regulated molecules relevant in inflammatory brain diseases, we investigated its expression in normal and pathological human brains [33].
  • Available research provides compelling theoretic, basic biologic and clinical support for the notion that ADHD is a brain disorder of likely genetic etiology with etiologic and pathophysiologic heterogeneity [34].
  • In contrast, caspase-3-deficient C57BL/6J mice reached adulthood, were fertile and showed minimal brain pathology [35].
 

Analytical, diagnostic and therapeutic context of Brain Diseases

References

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