Gene Review:
FGD1 - FYVE, RhoGEF and PH domain containing 1
Homo sapiens
Synonyms:
AAS, FGDY, FYVE, RhoGEF and PH domain-containing protein 1, Faciogenital dysplasia 1 protein, MRXS16, ...
Hayakawa,
Kitagawa,
Miyazawa,
Kitagawa,
Kikugawa,
Gorski,
Estrada,
Hu,
Liu,
Lebel,
May,
Pouls,
Lubs,
Stevenson,
Schwartz,
Orrico,
Galli,
Cavaliere,
Garavelli,
Fryns,
Crushell,
Rinaldi,
Medeira,
Sorrentino,
Orrico,
Galli,
Buoni,
Hayek,
Luchetti,
Lorenzini,
Zappella,
Pomponi,
Sorrentino,
Orrico,
Galli,
Falciani,
Bracci,
Cavaliere,
Rinaldi,
Musacchio,
Sorrentino,
- Skeletal-specific expression of Fgd1 during bone formation and skeletal defects in faciogenital dysplasia (FGDY; Aarskog syndrome). Gorski, J.L., Estrada, L., Hu, C., Liu, Z. Dev. Dyn. (2000)
- Non-syndromic X-linked mental retardation associated with a missense mutation (P312L) in the FGD1 gene. Lebel, R.R., May, M., Pouls, S., Lubs, H.A., Stevenson, R.E., Schwartz, C.E. Clin. Genet. (2002)
- Attention-deficit/hyperactivity disorder (ADHD) and variable clinical expression of Aarskog-Scott syndrome due to a novel FGD1 gene mutation (R408Q). Orrico, A., Galli, L., Buoni, S., Hayek, G., Luchetti, A., Lorenzini, S., Zappella, M., Pomponi, M.G., Sorrentino, V. Am. J. Med. Genet. A (2005)
- Terminal cytoplasmic maturation of human megakaryocytes in vitro. Straneva, J.E., Goheen, M.P., Hui, S.L., Bruno, E., Hoffman, R. Exp. Hematol. (1986)
- Sudden death from cord compression associated with atlanto-axial instability in rheumatoid arthritis. A case report. Yaszemski, M.J., Shepler, T.R. Spine. (1990)
- Phenotypic and molecular characterisation of the Aarskog-Scott syndrome: a survey of the clinical variability in light of FGD1 mutation analysis in 46 patients. Orrico, A., Galli, L., Cavaliere, M.L., Garavelli, L., Fryns, J.P., Crushell, E., Rinaldi, M.M., Medeira, A., Sorrentino, V. Eur. J. Hum. Genet. (2004)
- Adolescent anabolic steroid use and aggressive behavior in golden hamsters. Melloni, R.H., Ferris, C.F. Ann. N. Y. Acad. Sci. (1996)
- Psychiatric side effects induced by supraphysiological doses of combinations of anabolic steroids correlate to the severity of abuse. Pagonis, T.A., Angelopoulos, N.V., Koukoulis, G.N., Hadjichristodoulou, C.S. Eur. Psychiatry (2006)
- Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor. Pasteris, N.G., Cadle, A., Logie, L.J., Porteous, M.E., Schwartz, C.E., Stevenson, R.E., Glover, T.W., Wilroy, R.S., Gorski, J.L. Cell (1994)
- Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis. Manjunatha, U.H., Boshoff, H., Dowd, C.S., Zhang, L., Albert, T.J., Norton, J.E., Daniels, L., Dick, T., Pang, S.S., Barry, C.E. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape. Hou, P., Estrada, L., Kinley, A.W., Parsons, J.T., Vojtek, A.B., Gorski, J.L. Hum. Mol. Genet. (2003)
- Attention dysfunction in cirrhotic patients: an inquiry on the role of executive control, attention orienting and focusing. Amodio, P., Schiff, S., Del Piccolo, F., Mapelli, D., Gatta, A., Umiltà, C. Metabolic brain disease. (2005)
- Essential trace elements in humans. Serum arsenic concentrations in hemodialysis patients in comparison to healthy controls. Mayer, D.R., Kosmus, W., Pogglitsch, H., Mayer, D., Beyer, W. Biological trace element research. (1993)
- Zinc, cadmium and selenium concentrations in separated epithelium and stroma from prostatic tissues of different histology. Feustel, A., Wennrich, R., Dittrich, H. Urol. Res. (1987)
- Diagnostic accuracy and factor structure of the AAS and APS scales of the MMPI-2. Clements, R., Heintz, J.M. Journal of personality assessment. (2002)
- Fgd1, the Cdc42 guanine nucleotide exchange factor responsible for faciogenital dysplasia, is localized to the subcortical actin cytoskeleton and Golgi membrane. Estrada, L., Caron, E., Gorski, J.L. Hum. Mol. Genet. (2001)
- Genomic organization of the faciogenital dysplasia (FGD1; Aarskog syndrome) gene. Pasteris, N.G., Buckler, J., Cadle, A.B., Gorski, J.L. Genomics (1997)
- Isolation, characterization, and mapping of the mouse Fgd3 gene, a new Faciogenital Dysplasia (FGD1; Aarskog Syndrome) gene homologue. Pasteris, N.G., Nagata, K., Hall, A., Gorski, J.L. Gene (2000)
- The Caenorhabditis elegans homolog of FGD1, the human Cdc42 GEF gene responsible for faciogenital dysplasia, is critical for excretory cell morphogenesis. Gao, J., Estrada, L., Cho, S., Ellis, R.E., Gorski, J.L. Hum. Mol. Genet. (2001)
- Isolation, characterization, and mapping of the mouse and human Fgd2 genes, faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologues. Pasteris, N.G., Gorski, J.L. Genomics (1999)
- Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases. Olson, M.F., Pasteris, N.G., Gorski, J.L., Hall, A. Curr. Biol. (1996)
- Novel alternative splicing of human faciogenital dysplasia 1 gene. Yanagi, K., Kaname, T., Chinen, Y., Naritomi, K. Congenital anomalies. (2004)
- The FWD1/beta-TrCP-mediated degradation pathway establishes a 'turning off switch' of a Cdc42 guanine nucleotide exchange factor, FGD1. Hayakawa, M., Kitagawa, H., Miyazawa, K., Kitagawa, M., Kikugawa, K. Genes Cells (2005)
- An intragenic TaqI polymorphism in the faciogenital dysplasia (FGD1) locus, the gene responsible for Aarskog syndrome. Pasteris, N.G., Gorski, J.L. Hum. Genet. (1995)
- Elimination of matrix and spectral interferences in the measurement of lead and cadmium in urine and blood by electrothermal atomic absorption spectrometry with deuterium background correction. D'Haese, P.C., Lamberts, L.V., Liang, L., Van de Vyver, F.L., De Broe, M.E. Clin. Chem. (1991)
- A mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome). Orrico, A., Galli, L., Falciani, M., Bracci, M., Cavaliere, M.L., Rinaldi, M.M., Musacchio, A., Sorrentino, V. FEBS Lett. (2000)
- Effect of Fgd1 on cortactin in Arp2/3 complex-mediated actin assembly. Kim, K., Hou, P., Gorski, J.L., Cooper, J.A. Biochemistry (2004)
- Beam injection flame furnace atomic absorption spectrometry: a new flame method. Gáspár, A., Berndt, H. Anal. Chem. (2000)
- Improved 32P-postlabelling assay for the quantification of the major platinum-DNA adducts. Welters, M.J., Maliepaard, M., Jacobs-Bergmans, A.J., Baan, R.A., Schellens, J.H., Ma, J., van der Vijgh, W.J., Braakhuis, B.J., Fichtinger-Schepman, A.M. Carcinogenesis (1997)