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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Factor Analysis, Statistical

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Disease relevance of Factor Analysis, Statistical


Psychiatry related information on Factor Analysis, Statistical


High impact information on Factor Analysis, Statistical


Chemical compound and disease context of Factor Analysis, Statistical


Biological context of Factor Analysis, Statistical


Anatomical context of Factor Analysis, Statistical

  • We used structural equation modeling, a technique that merges the analytic procedures of factor analysis and multiple regression, to examine the reliability and construct validity of the Middle Cerebral Artery Neurological Scale and the Scandinavian Neurological Stroke Scale used together as the Unified Neurological Stroke Scale [25].
  • In anesthetized cats with cervical spinal cord transection, Fano factor analysis was used to test for time-scale invariant (fractal) fluctuations in spike counts of single preganglionic cervical sympathetic neurons (PSNs) and putative sympathetic premotor neurons located in the rostral ventrolateral medulla (RVLM) and caudal medullary raphe [26].
  • Presurgical localization of abnormal parathyroid glands using a single injection of technetium-99m methoxyisobutylisonitrile: comparison of different techniques including factor analysis of dynamic structures [27].
  • Diagnosis of malignancy in thyroid nodules by factor analysis of spectral and dynamic structures: a simultaneous dual-isotope dynamic study with thallium-201 and iodine-131 [28].
  • Jurkat cells were cultured in biotin-deficient (0.025 nmol/L) and biotin-supplemented (10 nmol/L) media for 5 wk prior to transcription factor analysis [29].

Associations of Factor Analysis, Statistical with chemical compounds


Gene context of Factor Analysis, Statistical

  • We then used factor analysis to relate changes in performance in these tasks with cholinergic markers, somatostatin levels, and amyloid burden [35].
  • Factor analysis produced two underlying factors, ie the 'inflammation' factor, including CRP, fibrinogen and IL-6, and the 'injury' factor, including troponin T, creatine kinase MB mass and TNF-alpha [36].
  • However, as indicated by factor analysis, the prognostic information yielded by mitosin was superior to that provided by the remaining proliferation markers (p = 0.041) [37].
  • On factor analysis, procoagulant factors VII and X, proteins C and S, and plasminogen activator inhibitor-1 were components of the cluster of variables that explained the greatest proportion of the variance in the data (39.2%) [38].
  • Growth factor analysis was done by analysing for expression of epidermal growth factor (EGF), epidermal growth factor receptor (EGF-R) and transforming growth factors alpha and beta (TGFalpha, TGFbeta) [39].

Analytical, diagnostic and therapeutic context of Factor Analysis, Statistical


  1. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: a pilot prognostic factor analysis. Whitehead, V.M., Rosenblatt, D.S., Vuchich, M.J., Shuster, J.J., Witte, A., Beaulieu, D. Blood (1990) [Pubmed]
  2. The Multiple Sclerosis Impact Scale (MSIS-29): a new patient-based outcome measure. Hobart, J., Lamping, D., Fitzpatrick, R., Riazi, A., Thompson, A. Brain (2001) [Pubmed]
  3. Efficacy of combined 5-fluorouracil and cisplatinum in advanced gastric carcinomas. A phase II trial with prognostic factor analysis. Rougier, P., Ducreux, M., Mahjoubi, M., Pignon, J.P., Bellefqih, S., Oliveira, J., Bognel, C., Lasser, P., Ychou, M., Elias, D. Eur. J. Cancer (1994) [Pubmed]
  4. Appetitive and consummatory sexual behaviors of female rats in bilevel chambers. I. A correlational and factor analysis and the effects of ovarian hormones. Pfaus, J.G., Smith, W.J., Coopersmith, C.B. Hormones and behavior. (1999) [Pubmed]
  5. The central roles of obesity-associated dyslipidaemia, endothelial activation and cytokines in the Metabolic Syndrome--an analysis by structural equation modelling. Chan, J.C., Cheung, J.C., Stehouwer, C.D., Emeis, J.J., Tong, P.C., Ko, G.T., Yudkin, J.S. Int. J. Obes. Relat. Metab. Disord. (2002) [Pubmed]
  6. Cannabinoid receptor gene (CNR1): association with i.v. drug use. Comings, D.E., Muhleman, D., Gade, R., Johnson, P., Verde, R., Saucier, G., MacMurray, J. Mol. Psychiatry (1997) [Pubmed]
  7. Factorial composition of self-rated schizotypal traits among young males undergoing military training. Stefanis, N.C., Smyrnis, N., Avramopoulos, D., Evdokimidis, I., Ntzoufras, I., Stefanis, C.N. Schizophrenia bulletin. (2004) [Pubmed]
  8. Prejudice toward fat people: the development and validation of the antifat attitudes test. Lewis, R.J., Cash, T.F., Jacobi, L., Bubb-Lewis, C. Obes. Res. (1997) [Pubmed]
  9. Effects of early intervention on cognitive function of low birth weight preterm infants. Brooks-Gunn, J., Liaw, F.R., Klebanov, P.K. J. Pediatr. (1992) [Pubmed]
  10. Validation of an instrument measuring patient satisfaction with chest physiotherapy techniques in cystic fibrosis. Oermann, C.M., Swank, P.R., Sockrider, M.M. Chest (2000) [Pubmed]
  11. Natural antibodies sustain differentiation and maturation of human dendritic cells. Bayry, J., Lacroix-Desmazes, S., Donkova-Petrini, V., Carbonneil, C., Misra, N., Lepelletier, Y., Delignat, S., Varambally, S., Oksenhendler, E., Lévy, Y., Debré, M., Kazatchkine, M.D., Hermine, O., Kaveri, S.V. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  12. Bone loss following hematopoietic stem cell transplantation: a long-term follow-up. Schulte, C.M., Beelen, D.W. Blood (2004) [Pubmed]
  13. All-trans retinoic acid in acute promyelocytic leukemia: long-term outcome and prognostic factor analysis from the North American Intergroup protocol. Tallman, M.S., Andersen, J.W., Schiffer, C.A., Appelbaum, F.R., Feusner, J.H., Woods, W.G., Ogden, A., Weinstein, H., Shepherd, L., Willman, C., Bloomfield, C.D., Rowe, J.M., Wiernik, P.H. Blood (2002) [Pubmed]
  14. An informatics approach identifying markers of chemosensitivity in human cancer cell lines. Amundson, S.A., Myers, T.G., Scudiero, D., Kitada, S., Reed, J.C., Fornace, A.J. Cancer Res. (2000) [Pubmed]
  15. Concurrent chemotherapy and radiation therapy followed by transhiatal esophagectomy for local-regional cancer of the esophagus. Forastiere, A.A., Orringer, M.B., Perez-Tamayo, C., Urba, S.G., Husted, S., Takasugi, B.J., Zahurak, M. J. Clin. Oncol. (1990) [Pubmed]
  16. Factor analysis of laboratory and clinical measurements of dyspnea in patients with chronic obstructive pulmonary disease. Nguyen, H.Q., Altinger, J., Carrieri-Kohlman, V., Gormley, J.M., Stulbarg, M.S. Journal of pain and symptom management. (2003) [Pubmed]
  17. A multivariate factor analysis of the high plasma concentration of cyclic AMP in patients with chronic renal failure. Marumo, F., Sakai, T., Shirataka, M. The International journal of artificial organs. (1980) [Pubmed]
  18. Prognostic factor analysis in advanced gastric cancer patients treated with hydroxyurea, leucovorin, 5-fluorouracil, and cisplatin (HLFP regimen). Louvet, C., Carrat, F., Mal, F., Mabro, M., Beerblock, K., Vaillant, J.C., Cady, J., André, T., Gamelin, E., de Gramont, A. Cancer Invest. (2003) [Pubmed]
  19. Coherence of the dependence syndrome in cocaine users. Bryant, K.J., Rounsaville, B.J., Babor, T.F. British journal of addiction. (1991) [Pubmed]
  20. Stressors and social support perceptions predict illness attitudes and care-seeking intentions: re-examining the sick role. Miczo, N. Health communication. (2004) [Pubmed]
  21. Inflammation markers and erythrocyte sedimentation rate but not metabolic syndrome factor score predict coronary heart disease in high socioeconomic class males: the HDDRISC study. Godsland, I.F., Bruce, R., Jeffs, J.A., Leyva, F., Walton, C., Stevenson, J.C. International journal of cardiology. (2004) [Pubmed]
  22. Influence and correction of temperature perturbations on NIR spectra during the monitoring of a polymorph conversion process prior to self-modelling mixture analysis. DeBraekeleer, K., Cuesta Sánchez, F., Hailey, P.A., Sharp, D.C., Pettman, A.J., Massart, D.L. Journal of pharmaceutical and biomedical analysis. (1998) [Pubmed]
  23. Factors underlying individual differences in the color matches of normal observers. Webster, M.A., MacLeod, D.I. Journal of the Optical Society of America. A, Optics and image science. (1988) [Pubmed]
  24. Factor analysis of cluster-specific gene expression levels from cDNA microarrays. Peterson, L.E. Computer methods and programs in biomedicine. (2002) [Pubmed]
  25. Unified Neurological Stroke Scale is valid in ischemic and hemorrhagic stroke. Edwards, D.F., Chen, Y.W., Diringer, M.N. Stroke (1995) [Pubmed]
  26. Fractal activity generated independently by medullary sympathetic premotor and preganglionic sympathetic neurons. Orer, H.S., Das, M., Barman, S.M., Gebber, G.L. J. Neurophysiol. (2003) [Pubmed]
  27. Presurgical localization of abnormal parathyroid glands using a single injection of technetium-99m methoxyisobutylisonitrile: comparison of different techniques including factor analysis of dynamic structures. Blocklet, D., Martin, P., Schoutens, A., Verhas, M., Hooghe, L., Kinnaert, P. European journal of nuclear medicine. (1997) [Pubmed]
  28. Diagnosis of malignancy in thyroid nodules by factor analysis of spectral and dynamic structures: a simultaneous dual-isotope dynamic study with thallium-201 and iodine-131. Helal, B.O., Frouin, F., Schaison, G., Leguillouzic, D., Pueyo, M.E., Lebtahi, R., Archambaud, F., Desgrez, A., Bazin, J.P., Di Paola, R. European journal of nuclear medicine. (1992) [Pubmed]
  29. The nuclear abundance of transcription factors Sp1 and Sp3 depends on biotin in Jurkat cells. Griffin, J.B., Rodriguez-Melendez, R., Zempleni, J. J. Nutr. (2003) [Pubmed]
  30. Components of the "metabolic syndrome" and incidence of type 2 diabetes. Hanson, R.L., Imperatore, G., Bennett, P.H., Knowler, W.C. Diabetes (2002) [Pubmed]
  31. Patterns of cortical activity and memory performance in Alzheimer's disease. Schröder, J., Buchsbaum, M.S., Shihabuddin, L., Tang, C., Wei, T.C., Spiegel-Cohen, J., Hazlett, E.A., Abel, L., Luu-Hsia, C., Ciaravolo, T.M., Marin, D., Davis, K.L. Biol. Psychiatry (2001) [Pubmed]
  32. Serum uric acid as an index of impaired oxidative metabolism in chronic heart failure. Leyva, F., Anker, S., Swan, J.W., Godsland, I.F., Wingrove, C.S., Chua, T.P., Stevenson, J.C., Coats, A.J. Eur. Heart J. (1997) [Pubmed]
  33. Relationships among quality of life, severity, and control measures in asthma: an evaluation using factor analysis. Schatz, M., Mosen, D., Apter, A.J., Zeiger, R.S., Vollmer, W.M., Stibolt, T.B., Leong, A., Johnson, M.S., Mendoza, G., Cook, E.F. J. Allergy Clin. Immunol. (2005) [Pubmed]
  34. Adiponectin in a native Canadian population experiencing rapid epidemiological transition. Hanley, A.J., Connelly, P.W., Harris, S.B., Zinman, B. Diabetes Care (2003) [Pubmed]
  35. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. Savonenko, A., Xu, G.M., Melnikova, T., Morton, J.L., Gonzales, V., Wong, M.P., Price, D.L., Tang, F., Markowska, A.L., Borchelt, D.R. Neurobiol. Dis. (2005) [Pubmed]
  36. C-reactive protein, fibrinogen, interleukin-6 and tumour necrosis factor-alpha in the prognostic classification of unstable angina pectoris. Koukkunen, H., Penttilä, K., Kemppainen, A., Halinen, M., Penttila, I., Rantanen, T., Pyörälä, K. Ann. Med. (2001) [Pubmed]
  37. Mitosin, a novel marker of cell proliferation and early recurrence in intracranial meningiomas. Konstantinidou, A.E., Korkolopoulou, P., Kavantzas, N., Mahera, H., Thymara, I., Kotsiakis, X., Perdiki, M., Patsouris, E., Davaris, P. Histol. Histopathol. (2003) [Pubmed]
  38. Hemostatic risk factors and insulin sensitivity, regional body fat distribution, and the metabolic syndrome. Godsland, I.F., Crook, D., Proudler, A.J., Stevenson, J.C. J. Clin. Endocrinol. Metab. (2005) [Pubmed]
  39. Tumour-proliferative fraction and growth factor expression as markers of tumour response to radiotherapy in cancer of the uterine cervix. Pillai, M.R., Jayaprakash, P.G., Nair, M.K. J. Cancer Res. Clin. Oncol. (1998) [Pubmed]
  40. Effect of urea on the polymer buffer solutions used for the electrophoretic separations of nucleic acids. Todorov, T.I., Yamaguchi, Y., Morris, M.D. Anal. Chem. (2003) [Pubmed]
  41. Confirmatory factor analysis of a 4-factor model of chronic pain evaluation. De Gagné, T.A., Mikail, S.F., D'Eon, J.L. Pain (1995) [Pubmed]
  42. Latent class and factor analysis of DSM-IV ADHD: a twin study of female adolescents. Hudziak, J.J., Heath, A.C., Madden, P.F., Reich, W., Bucholz, K.K., Slutske, W., Bierut, L.J., Neuman, R.J., Todd, R.D. Journal of the American Academy of Child and Adolescent Psychiatry. (1998) [Pubmed]
  43. Structure of four executive functioning tests in healthy older adults. de Frias, C.M., Dixon, R.A., Strauss, E. Neuropsychology. (2006) [Pubmed]
  44. A confirmatory factor analysis of the Center for Epidemiologic Studies Depression Scale in rheumatoid arthritis patients: additional evidence for a four-factor model. Rhee, S.H., Petroski, G.F., Parker, J.C., Smarr, K.L., Wright, G.E., Multon, K.D., Buchholz, J.L., Komatireddy, G.R. Arthritis care and research : the official journal of the Arthritis Health Professions Association. (1999) [Pubmed]
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