Gene Review:
Lnpep - leucyl/cystinyl aminopeptidase
Mus musculus
Synonyms:
2010309L07Rik, 4732490P18Rik, CAP, Cystinyl aminopeptidase, IRAP, ...
- Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs. Takahashi, H., Takeshita, T., Morein, B., Putney, S., Germain, R.N., Berzofsky, J.A. Nature (1990)
- Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity. Belyakov, I.M., Moss, B., Strober, W., Berzofsky, J.A. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Cell surface antigens of human renal cancer defined by mouse monoclonal antibodies: identification of tissue-specific kidney glycoproteins. Ueda, R., Ogata, S., Morrissey, D.M., Finstad, C.L., Szkudlarek, J., Whitmore, W.F., Oettgen, H.F., Lloyd, K.O., Old, L.J. Proc. Natl. Acad. Sci. U.S.A. (1981)
- Growth inhibition of murine melanoma cells by antibodies to a cell surface glycoprotein implicated in retinoic acid action. Lotan, R., Lotan, D., Deutsch, V. Cancer Res. (1987)
- HIV-1 neutralizing antibodies in the genital and respiratory tracts of mice intranasally immunized with oligomeric gp160. VanCott, T.C., Kaminski, R.W., Mascola, J.R., Kalyanaraman, V.S., Wassef, N.M., Alving, C.R., Ulrich, J.T., Lowell, G.H., Birx, D.L. J. Immunol. (1998)
- Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals. Clerici, M., Stocks, N.I., Zajac, R.A., Boswell, R.N., Bernstein, D.C., Mann, D.L., Shearer, G.M., Berzofsky, J.A. Nature (1989)
- Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity. Oh, S., Berzofsky, J.A., Burke, D.S., Waldmann, T.A., Perera, L.P. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance. Actor, J.K., Shirai, M., Kullberg, M.C., Buller, R.M., Sher, A., Berzofsky, J.A. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Glut4 storage vesicles without Glut4: transcriptional regulation of insulin-dependent vesicular traffic. Gross, D.N., Farmer, S.R., Pilch, P.F. Mol. Cell. Biol. (2004)
- Munc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles. Thurmond, D.C., Kanzaki, M., Khan, A.H., Pessin, J.E. Mol. Cell. Biol. (2000)
- Polyarginine inhibits gp160 processing by furin and suppresses productive human immunodeficiency virus type 1 infection. Kibler, K.V., Miyazato, A., Yedavalli, V.S., Dayton, A.I., Jacobs, B.L., Dapolito, G., Kim, S.J., Jeang, K.T. J. Biol. Chem. (2004)
- Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity. Page, K.A., Landau, N.R., Littman, D.R. J. Virol. (1990)
- Adjuvanticity of stearyl tyrosine on the antibody response to peptide 503-535 from HIV gp160. Bona, C., Nixon, A., Kennedy, R., Zaghouani, H. AIDS Res. Hum. Retroviruses (1992)
- Comparisons of DNA-mediated immunization procedures directed against surface glycoproteins of human immunodeficiency virus type-1 and hepatitis B virus. Fomsgaard, A., Nielsen, H.V., Nielsen, C., Johansson, K., Machuca, R., Bruun, L., Hansen, J., Buus, S. APMIS (1998)
- Immunohistochemical expression of monoclonal antibody 43-9F in testicular germ cell tumours. Heidenreich, A., Sesterhenn, I.A., Mostofi, F.K., Moul, J.W. Int. J. Androl. (1998)
- Mice deficient in the insulin-regulated membrane aminopeptidase show substantial decreases in glucose transporter GLUT4 levels but maintain normal glucose homeostasis. Keller, S.R., Davis, A.C., Clairmont, K.B. J. Biol. Chem. (2002)
- HIV mucosal vaccine: nasal immunization with gp160-encapsulated hemagglutinating virus of Japan-liposome induces antigen-specific CTLs and neutralizing antibody responses. Sakaue, G., Hiroi, T., Nakagawa, Y., Someya, K., Iwatani, K., Sawa, Y., Takahashi, H., Honda, M., Kunisawa, J., Kiyono, H. J. Immunol. (2003)
- M cell DNA vaccination for CTL immunity to HIV. Wang, X., Hone, D.M., Haddad, A., Shata, M.T., Pascual, D.W. J. Immunol. (2003)
- The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway. Ruff, A.L., Guarnieri, F.G., Staveley-O'Carroll, K., Siliciano, R.F., August, J.T. J. Biol. Chem. (1997)
- Characterization of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes. Ross, S.A., Scott, H.M., Morris, N.J., Leung, W.Y., Mao, F., Lienhard, G.E., Keller, S.R. J. Biol. Chem. (1996)
- p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation. Hosaka, T., Brooks, C.C., Presman, E., Kim, S.K., Zhang, Z., Breen, M., Gross, D.N., Sztul, E., Pilch, P.F. Mol. Biol. Cell (2005)
- Regulation of insulin-responsive aminopeptidase expression and targeting in the insulin-responsive vesicle compartment of glucose transporter isoform 4-deficient cardiomyocytes. Abel, E.D., Graveleau, C., Betuing, S., Pham, M., Reay, P.A., Kandror, V., Kupriyanova, T., Xu, Z., Kandror, K.V. Mol. Endocrinol. (2004)
- Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein. Takahashi, H., Houghten, R., Putney, S.D., Margulies, D.H., Moss, B., Germain, R.N., Berzofsky, J.A. J. Exp. Med. (1989)
- Characterization of a monoclonal antibody specific for the HIV-1 precursor glycoprotein. Krust, B., Laurent, A.G., Le Guern, A., Jeannequin, O., Montagnier, L., Hovanessian, A.G. AIDS (1988)
- Morphology surface of a mouse plasmacytoma (LPC-1) showing cyclic resistance to immune lysis. Rosenstein, Y., Osornio-Vargas, A.R. Lab. Invest. (1986)
- The amino terminus of insulin-responsive aminopeptidase causes Glut4 translocation in 3T3-L1 adipocytes. Waters, S.B., D'Auria, M., Martin, S.S., Nguyen, C., Kozma, L.M., Luskey, K.L. J. Biol. Chem. (1997)
- The glucose transporter GLUT4 and the aminopeptidase vp165 colocalise in tubulo-vesicular elements in adipocytes and cardiomyocytes. Martin, S., Rice, J.E., Gould, G.W., Keller, S.R., Slot, J.W., James, D.E. J. Cell. Sci. (1997)
- GLUT4 overexpression or deficiency in adipocytes of transgenic mice alters the composition of GLUT4 vesicles and the subcellular localization of GLUT4 and insulin-responsive aminopeptidase. Carvalho, E., Schellhorn, S.E., Zabolotny, J.M., Martin, S., Tozzo, E., Peroni, O.D., Houseknecht, K.L., Mundt, A., James, D.E., Kahn, B.B. J. Biol. Chem. (2004)
- Glut4 is targeted to specific vesicles in adipocytes of transgenic mice overexpressing Glut4 selectively in adipose tissue. Tozzo, E., Kahn, B.B., Pilch, P.F., Kandror, K.V. J. Biol. Chem. (1996)