Gene Review:
Sh - Shaker
Drosophila melanogaster
Synonyms:
BcDNA:GH03046, CG12348, CG17860, CG7640, Dmel\CG12348, ...
- Calnexin co-expression and the use of weaker promoters increase the expression of correctly assembled Shaker potassium channel in insect cells. Higgins, M.K., Demir, M., Tate, C.G. Biochim. Biophys. Acta (2003)
- Adenovirus-mediated expression of a voltage-gated potassium channel in vitro (rat cardiac myocytes) and in vivo (rat liver). A novel strategy for modifying excitability. Johns, D.C., Nuss, H.B., Chiamvimonvat, N., Ramza, B.M., Marban, E., Lawrence, J.H. J. Clin. Invest. (1995)
- Functional expression of Shaker K+ channels in a baculovirus-infected insect cell line. Klaiber, K., Williams, N., Roberts, T.M., Papazian, D.M., Jan, L.Y., Miller, C. Neuron (1990)
- Expression of Drosophila Shaker potassium channels in mammalian cells infected with recombinant vaccinia virus. Leonard, R.J., Karschin, A., Jayashree-Aiyar, S., Davidson, N., Tanouye, M.A., Thomas, L., Thomas, G., Lester, H.A. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Cell-specific posttranslational events affect functional expression at the plasma membrane but not tetrodotoxin sensitivity of the rat brain IIA sodium channel alpha-subunit expressed in mammalian cells. Yang, X.C., Labarca, C., Nargeot, J., Ho, B.Y., Elroy-Stein, O., Moss, B., Davidson, N., Lester, H.A. J. Neurosci. (1992)
- Genetic analysis of oxygen defense mechanisms in Drosophila melanogaster and identification of a novel behavioural mutant with a Shaker phenotype. Humphreys, J.M., Duyf, B., Joiner, M.L., Phillips, J.P., Hilliker, A.J. Genome (1996)
- Reduced sleep in Drosophila Shaker mutants. Cirelli, C., Bushey, D., Hill, S., Huber, R., Kreber, R., Ganetzky, B., Tononi, G. Nature (2005)
- Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel. Kamb, A., Iverson, L.E., Tanouye, M.A. Cell (1987)
- The contribution of Shaker K+ channels to the information capacity of Drosophila photoreceptors. Niven, J.E., Vähäsöyrinki, M., Kauranen, M., Hardie, R.C., Juusola, M., Weckström, M. Nature (2003)
- Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila. Schwarz, T.L., Tempel, B.L., Papazian, D.M., Jan, Y.N., Jan, L.Y. Nature (1988)
- Cloning of a probable potassium channel gene from mouse brain. Tempel, B.L., Jan, Y.N., Jan, L.Y. Nature (1988)
- A potassium channel beta subunit related to the aldo-keto reductase superfamily is encoded by the Drosophila hyperkinetic locus. Chouinard, S.W., Wilson, G.F., Schlimgen, A.K., Ganetzky, B. Proc. Natl. Acad. Sci. U.S.A. (1995)
- A novel leg-shaking Drosophila mutant defective in a voltage-gated K(+)current and hypersensitive to reactive oxygen species. Wang, J.W., Humphreys, J.M., Phillips, J.P., Hilliker, A.J., Wu, C.F. J. Neurosci. (2000)
- Analysis of anesthetic action on the potassium channels of the Shaker mutant of Drosophila. Tinklenberg, J.A., Segal, I.S., Guo, T.Z., Maze, M. Ann. N. Y. Acad. Sci. (1991)
- Development of larval muscle properties in the embryonic myotubes of Drosophila melanogaster. Broadie, K.S., Bate, M. J. Neurosci. (1993)
- Expression of ion channel genes in Drosophila. Tseng-Crank, J., Pollock, J.A., Hayashi, I., Tanouye, M.A. J. Neurogenet. (1991)
- Sub-cellular Ca(2+) dynamics affected by voltage- and Ca(2+)-gated K(+) channels: Regulation of the soma-growth cone disparity and the quiescent state in Drosophila neurons. Berke, B.A., Lee, J., Peng, I.F., Wu, C.F. Neuroscience (2006)
- Mutant Analysis of the Shal (Kv4) Voltage-gated Fast Transient K+ Channel in Caenorhabditis elegans. Fawcett, G.L., Santi, C.M., Butler, A., Harris, T., Covarrubias, M., Salkoff, L. J. Biol. Chem. (2006)
- Properties of potassium currents and their role in membrane excitability in Drosophila larval muscle fibers. Singh, S., Wu, C.F. J. Exp. Biol. (1990)
- The roles of potassium currents in Drosophila flight muscles. Elkins, T., Ganetzky, B. J. Neurosci. (1988)
- Serotonin modulates the voltage dependence of delayed rectifier and Shaker potassium channels in Drosophila photoreceptors. Hevers, W., Hardie, R.C. Neuron (1995)
- Conserved gating hinge in ligand- and voltage-dependent K+ channels. Magidovich, E., Yifrach, O. Biochemistry (2004)
- The shaker and shaking-B genes specify elements in the processing of gustatory information in Drosophila melanogaster. Balakrishnan, R., Rodrigues, V. J. Exp. Biol. (1991)
- In vivo functional role of the Drosophila hyperkinetic beta subunit in gating and inactivation of Shaker K+ channels. Wang, J.W., Wu, C.F. Biophys. J. (1996)
- Reduced transmitter release conferred by mutations in the slowpoke-encoded Ca2(+)-activated K+ channel gene of Drosophila. Warbington, L., Hillman, T., Adams, C., Stern, M. Invert. Neurosci. (1996)
- Apoptotic proteins Reaper and Grim induce stable inactivation in voltage-gated K+ channels. Avdonin, V., Kasuya, J., Ciorba, M.A., Kaplan, B., Hoshi, T., Iverson, L. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Morphological plasticity of motor axons in Drosophila mutants with altered excitability. Budnik, V., Zhong, Y., Wu, C.F. J. Neurosci. (1990)
- The major delayed rectifier in both Drosophila neurons and muscle is encoded by Shab. Tsunoda, S., Salkoff, L. J. Neurosci. (1995)
- Genetic analysis of Drosophila neurons: Shal, Shaw, and Shab encode most embryonic potassium currents. Tsunoda, S., Salkoff, L. J. Neurosci. (1995)
- Neurogenetic analysis of potassium currents in Drosophila: synergistic effects on neuromuscular transmission in double mutants. Ganetzky, B., Wu, C.F. J. Neurogenet. (1983)
- Alteration of potassium channel gating: molecular analysis of the Drosophila Sh5 mutation. Gautam, M., Tanouye, M.A. Neuron (1990)
- Molecular cloning of a member of a third class of Shaker-family K+ channel genes in mammals. McCormack, T., Vega-Saenz de Miera, E.C., Rudy, B. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence. Papazian, D.M., Timpe, L.C., Jan, Y.N., Jan, L.Y. Nature (1991)