The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Eccrine Glands

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Eccrine Glands


High impact information on Eccrine Glands


Biological context of Eccrine Glands


Anatomical context of Eccrine Glands


Associations of Eccrine Glands with chemical compounds


Gene context of Eccrine Glands

  • No staining of iNOS or bNOS was observed in the eccrine gland [23].
  • Co-expression of CEA-180, NCA-90, and BGP was consistent with differentiation towards the secretory part of eccrine glands or the transitional portion of proximal ducts [24].
  • CEA and SP1 stained the secretory and duct-lining cells of normal eccrine glands [25].
  • However, a differential expression of CEA and EMA was demonstrated in apocrine epithelia, mucous cells of eccrine glands, and sweat ducts [26].
  • Amyloid deposition was observed around eccrine glands in seven of nine patients [1].

Analytical, diagnostic and therapeutic context of Eccrine Glands

  • On electron microscopy, no focal destruction and degeneration of eccrine glands or ducts and of Schwann cell processes with or without nerve terminals or unmyelinated axons were observed in relation to adjacent amyloid deposition [1].


  1. Denervation of eccrine glands in patients with familial amyloidotic polyneuropathy type I. Ohnishi, A., Yamamoto, T., Murai, Y., Ando, Y., Ando, M., Hoshii, Y., Ikeda, M. Neurology (1998) [Pubmed]
  2. Nodular hidradenoma. A report of three cases and review of the literature. Stratigos, A.J., Olbricht, S., Kwan, T.H., Bowers, K.E. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. (1998) [Pubmed]
  3. Two cases of coma-associated bulla with eccrine gland necrosis in patients without drug intoxication. Kim, K.J., Suh, H.S., Choi, J.H., Sung, K.J., Moon, K.C., Koh, J.K. Acta Derm. Venereol. (2002) [Pubmed]
  4. Genetic changes in sweat gland carcinomas. Takata, M., Hashimoto, K., Mehregan, P., Lee, M.W., Yamamoto, A., Mohri, S., Ohara, K., Takehara, K. J. Cutan. Pathol. (2000) [Pubmed]
  5. Hypertrophic eccrine glands in eccrine angiomatous hamartoma produce gross cystic disease fluid protein 15. Tanaka, M., Shimizu, S., Miyakawa, S. Dermatology (Basel) (2000) [Pubmed]
  6. Colocalization of 11 beta-hydroxysteroid dehydrogenase type II and mineralocorticoid receptor in human epithelia. Hirasawa, G., Sasano, H., Takahashi, K., Fukushima, K., Suzuki, T., Hiwatashi, N., Toyota, T., Krozowski, Z.S., Nagura, H. J. Clin. Endocrinol. Metab. (1997) [Pubmed]
  7. Distribution of beta 1, alpha 1, alpha 2 and alpha 3 integrin chains in basal cell carcinomas. Stamp, G.W., Pignatelli, M. J. Pathol. (1991) [Pubmed]
  8. Cathelicidin anti-microbial peptide expression in sweat, an innate defense system for the skin. Murakami, M., Ohtake, T., Dorschner, R.A., Schittek, B., Garbe, C., Gallo, R.L. J. Invest. Dermatol. (2002) [Pubmed]
  9. Expression, candidate gene, and population studies of the melanocortin 5 receptor. Hatta, N., Dixon, C., Ray, A.J., Phillips, S.R., Cunliffe, W.J., Dale, M., Todd, C., Meggit, S., Birch-MacHin, M.A., Rees, J.L. J. Invest. Dermatol. (2001) [Pubmed]
  10. 15-Lipoxygenase-2 expression in benign and neoplastic sebaceous glands and other cutaneous adnexa. Shappell, S.B., Keeney, D.S., Zhang, J., Page, R., Olson, S.J., Brash, A.R. J. Invest. Dermatol. (2001) [Pubmed]
  11. Plasma aldosterone and sweat sodium concentrations after exercise and heat acclimation. Kirby, C.R., Convertino, V.A. J. Appl. Physiol. (1986) [Pubmed]
  12. Vasoactive intestinal peptide (VIP) and peptide histidine methionine (PHM) in human eccrine sweat glands: demonstration of innervation, specific binding sites and presence in secretions. Eedy, D.J., Shaw, C., Armstrong, E.P., Johnston, C.F., Buchanan, K.D. Br. J. Dermatol. (1990) [Pubmed]
  13. Distribution of CD44 variant isoforms in human skin: differential expression in components of benign and malignant epithelia. Hale, L.P., Patel, D.D., Clark, R.E., Haynes, B.F. J. Cutan. Pathol. (1995) [Pubmed]
  14. Immunocytochemical localization of androgen receptors in human skin using monoclonal antibodies against the androgen receptor. Liang, T., Hoyer, S., Yu, R., Soltani, K., Lorincz, A.L., Hiipakka, R.A., Liao, S. J. Invest. Dermatol. (1993) [Pubmed]
  15. The melanocortin 5 receptor is expressed in human sebaceous glands and rat preputial cells. Thiboutot, D., Sivarajah, A., Gilliland, K., Cong, Z., Clawson, G. J. Invest. Dermatol. (2000) [Pubmed]
  16. Infantile hemangiomas: speculation on placental trophoblastic origin. Bree, A.F., Siegfried, E., Sotelo-Avila, C., Nahass, G. Archives of dermatology. (2001) [Pubmed]
  17. Immunohistochemical demonstration of breast-derived and/or carcinoma-associated glycoproteins in normal skin appendages and their tumors. Tsubura, A., Senzaki, H., Sasaki, M., Hilgers, J., Morii, S. J. Cutan. Pathol. (1992) [Pubmed]
  18. Ultrastructural localization of lectin-binding sites in normal human eccrine and apocrine glands. Schaumburg-Lever, G., Metzler, G., Tronnier, M. J. Dermatol. Sci. (1991) [Pubmed]
  19. Effect of isotretinoin on eccrine gland function. Rees, J.L., Cox, N.H. Br. J. Dermatol. (1988) [Pubmed]
  20. Structural changes in axillary eccrine glands following long-term treatment with aluminium chloride hexahydrate solution. Hölzle, E., Braun-Falco, O. Br. J. Dermatol. (1984) [Pubmed]
  21. Radiation response of murine eccrine sweat glands. Johns, H., Morris, W.J., Joiner, M.C. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. (1995) [Pubmed]
  22. Immunohistochemical localization of cytokeratins in normal eccrine glands, with monoclonal antibodies in routinely processed, formalin-fixed, paraffin-embedded sections. Watanabe, S., Ichikawa, E., Takanashi, S., Takahashi, H. J. Am. Acad. Dermatol. (1993) [Pubmed]
  23. Expression of endothelial nitric oxide synthase in human eccrine clear cells. Shimizu, Y., Sakai, M., Umemura, Y., Ueda, H. Br. J. Dermatol. (1997) [Pubmed]
  24. Neoplasms with sweat gland differentiation express various glycoproteins of the carcinoembryonic antigen (CEA) family. Metze, D., Grunert, F., Neumaier, M., Bhardwaj, R., Amann, U., Wagener, C., Luger, T.A. J. Cutan. Pathol. (1996) [Pubmed]
  25. Immunohistochemical markers of sweat gland tumors. Maiorana, A., Nigrisoli, E., Papotti, M. J. Cutan. Pathol. (1986) [Pubmed]
  26. Ultrastructural localization of carcinoembryonic antigen (CEA) glycoproteins and epithelial membrane antigen (EMA) in normal and neoplastic sweat glands. Metze, D., Luger, T.A. J. Cutan. Pathol. (1996) [Pubmed]
WikiGenes - Universities