Disease relevance of Hemianopsia

• BACKGROUND AND PURPOSE: Patients with hemiparesis, hemisensory loss, and hemianopsia ("HHH" deficits) due to stroke may have large cortical lesions caused by middle cerebral trunk vessel occlusion or smaller subcortical lesions due to lenticulostriate involvement [1].
• RESULTS: In no patient had the involvement of the anterior choroidal territory infarcts been recognized clinically, nor had the triad of clinical signs (hemiplegia, hemianesthesia, and hemianopsia) classically seen in infarcts restricted to this territory been found alone [2].
• CASE DESCRIPTION: We studied a 24-year-old man with MELAS who had fluent aphasia and right hemianopia [3].
• In addition, horizontal bar bisection showed a shift of the egocentric midline towards the scotoma in all four patients with left- or right-sided homonymous hemianopia [4].
• A 39-year-old woman experienced severe headache, epilepsy and rapidly progressive aphasia and hemianopia [5].

Psychiatry related information on Hemianopsia

• The controversial history of functional hemianopsia is reviewed from Briquet's 1859 monograph on 430 cases of hysteria, through the 19th century works of Charcot, Freud, and Janet, and the observations of Fox and Wilbrand and Saenger in the early 20th century [6].
• CONCLUSIONS: The low glucose metabolism in the right visual cortex explains the persistent left hemianopia, and that in the right anterior cingulate gyrus and the right temporal-parietal-occipital junction may be responsible for the left hemispatial neglect [7].

High impact information on Hemianopsia

• Eight patients were evaluated with 18F-fluorodeoxyglucose positron emission tomography between 3 and 30 days after isolated stroke involving the middle cerebral artery territory that caused homonymous hemianopia [8].
• A 36-year-old man being treated with cisplatinum, vinblastine, and bleomycin for testicular carcinoma developed a dense left homonymous hemianopsia, encephalopathy, and a partial nondominant parietal lobe syndrome [9].
• There was panhypopituitarism on endocrine testing and visual field examination showed inexorably progressive loss to bitemporal hemianopsia [10].
• A 25-year-old man with a long history of temporal lobe epilepsy developed right occipital lobe seizures and a progressive right homonymous hemianopia [11].
• This study compared admission and discharge functional outcome (Functional Independence Measure, FIM) and deficit severity (Fugl-Meyer, F-M) scores in a retrospective study of patients with similar neurologic impairments: homonymous hemianopia, hemisensory loss, and hemiparesis [12].

Chemical compound and disease context of Hemianopsia

• Transient left homonymous hemianopsia and encephalopathy following treatment of testicular carcinoma with cisplatinum, vinblastine, and bleomycin [9].
• RESULTS: Of the 14 patients, three had no loss or non-specific loss, eight had partial homonymous quadrantanopia, one had complete homonymous quadrantanopia and two had concentric loss attributable to vigabatrin, which may have masked any loss occurring due to surgery [13].
• Resolution of the homonymous hemianopia and the patient's symptoms came with normalization of her blood glucose levels [14].
• Two spatio-temporal filters in human vision. 2. Selective modification in amblyopia, albinism, and hemianopia [15].
• In one patient, a transient homonymous hemianopia attributable to postoperative swelling completely resolved under steroid medication [16].

Biological context of Hemianopsia

• Recently, it has been suggested that the effect is simply due to either hemianopia [Brain 124 (2001) 527], or the combination of neglect and hemianopia [Neurology 52 (1999) 1845] [17].
• A young woman presented in the third trimester of pregnancy with a rapid onset of bitemporal hemianopia and reduced visual acuity caused by an unusual steroid responsive suprasellar tumor [18].

Anatomical context of Hemianopsia

• The permanent deficits were due to retinal artery occlusions (RAO) in 20 patients (4%), ischemic optic neuropathy (ION) in eight patients (1.5%), and homonymous hemianopsia (HH) in four patients (0.7%) [19].
• CLINICAL PRESENTATION: A 27-year-old man presented with panhypopituitarism, bitemporal hemianopsia, and mild right oculomotor nerve paralysis [20].
• Hypotheses on subgroup differences in mean scores in the domains "communication" and "mobility+personal care" could be confirmed (the discerned subgroups were: gender, having a partner, motor deficit of upper or lower extremity, urinary incontinence, higher cortical deficits, conjugate deviation of the eye, coma, hemianopsia) [21].
• For example, upper limb incoordination interfered with RPAB, language difficulties affected the Abbreviated Mental Test, and HAD, and hemianopia compromised both RPAB and FAST tests [22].

Gene context of Hemianopsia

• Other individual features atypical for LHON included lack of the characteristic LHON funduscopic appearance, bitemporal hemianopia, optic disc cupping, and premonitory episodes of transient visual loss [23].
• Also, test locations along the vertical midline in densely hemianopic areas were seen with FDT testing in some patients with hemianopia, probably due to light scatter across the vertical midline and into the uninvolved hemianopic field [24].
• The authors describe the case of a 36-year-old man who presented with bitemporal hemianopsia and a serum prolactin concentration of 1440 ng/ml [25].
• Lower altitudinal bilateral hemianopsia in a patient with moyamoya disease [26].
• After experiencing an initial coma for several days, the patient was found to have a right-sided homonymous hemianopsia and a right hemiparesis, which was more marked at the shoulder and was accompanied by preservation of finger movement [27].

Analytical, diagnostic and therapeutic context of Hemianopsia

• The triad of left hemiplegia, hemihypesthesia, and homonymous hemianopsia: implications for rehabilitation [28].
• Physical examination: left homonimous hemianopsia, left hemiparesis, no papilledema, diffuse hyperreflexia, slowness of movements [29].

References