The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Fundoplication


High impact information on Fundoplication

  • The presence of H. pylori was assessed at the first visit by histologic evaluation in the fundoplication group and by histologic and serologic evaluation in the omeprazole group [6].
  • Esophageal motor abnormalities in gastroesophageal reflux and the effects of fundoplication [7].
  • Immediate results showed a significantly lower operative morbidity rate (10.3% versus 26.7%, OR 0.33, RD -12%, NNT 8), shorter postoperative stay (3.1 versus 5.2 days, P = 0.03), and shorter sick leave (20.1 versus 35.8 days, P = 0.03) for laparoscopic versus open fundoplication [8].
  • In 30 of 37 patients the Belsey Mark IV fundoplication was judged successful based on symptom relief and healing of oesophagitis [9].
  • Clinical and endoscopic improvement followed fundoplication and acyclovir therapy, but VZV DNA and IE62 persisted in esophageal tissue [10].

Chemical compound and disease context of Fundoplication


Biological context of Fundoplication


Anatomical context of Fundoplication


Associations of Fundoplication with chemical compounds

  • The variables influencing the intraoperative measurement of lower oesophageal sphincter (LOS) pressure and a new method of assessing the effect of a fundal wrap on LOS function were investigated in 13 patients undergoing fundoplication [25].
  • METHODS: A total of 62 patients with both GER and asthma entered a randomized study of antireflux treatments for at least 2 yr: 24 controls (antacids as needed); 22 medical (ranitidine 150 mg t.i.d.); and 16 surgical (Nissen fundoplication) [26].
  • This study reports our experience with laparoscopic fundoplication and its effect on the pulmonary status of children with severe steroid-dependent reactive airway disease [11].
  • Following surgery, animals responded to a previously subemetic dose of a centrally acting opiate receptor agonist (loperamide), suggesting that fundoplication may sensitize the emetic reflex [27].
  • Esophageal body function improved significantly following partial posterior fundoplication without or with postoperative treatment with cisapride [14].

Gene context of Fundoplication


Analytical, diagnostic and therapeutic context of Fundoplication


  1. Gastroesophageal reflux and severe combined immunodeficiency. Boeck, A., Buckley, R.H., Schiff, R.I. J. Allergy Clin. Immunol. (1997) [Pubmed]
  2. Comparison of Nissen total and Lind partial transabdominal fundoplication in the treatment of gastro-oesophageal reflux. Walker, S.J., Holt, S., Sanderson, C.J., Stoddard, C.J. The British journal of surgery. (1992) [Pubmed]
  3. Bradycardia associated with hiatal hernia and gastroesophageal reflux relieved by surgery. Axelrod, F.B., Maayan, C., Hazzi, C., Bangaru, B.S., Shannon, D.C. Am. J. Gastroenterol. (1987) [Pubmed]
  4. Acid suppression therapy may not alter malignant progression in Barrett's metaplasia showing p53 protein accumulation. Carlson, N., Lechago, J., Richter, J., Sampliner, R.E., Peterson, L., Santella, R.M., Goldblum, J.R., Falk, G.W., Ertan, A., Younes, M. Am. J. Gastroenterol. (2002) [Pubmed]
  5. Acarbose treatment of postprandial hypoglycemia in children after Nissen fundoplication. Ng, D.D., Ferry, R.J., Kelly, A., Weinzimer, S.A., Stanley, C.A., Katz, L.E. J. Pediatr. (2001) [Pubmed]
  6. Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. Kuipers, E.J., Lundell, L., Klinkenberg-Knol, E.C., Havu, N., Festen, H.P., Liedman, B., Lamers, C.B., Jansen, J.B., Dalenback, J., Snel, P., Nelis, G.F., Meuwissen, S.G. N. Engl. J. Med. (1996) [Pubmed]
  7. Esophageal motor abnormalities in gastroesophageal reflux and the effects of fundoplication. Gill, R.C., Bowes, K.L., Murphy, P.D., Kingma, Y.J. Gastroenterology (1986) [Pubmed]
  8. Evidence-based appraisal of antireflux fundoplication. Catarci, M., Gentileschi, P., Papi, C., Carrara, A., Marrese, R., Gaspari, A.L., Grassi, G.B. Ann. Surg. (2004) [Pubmed]
  9. Prospective evaluation of 24 hour ambulatory pH metry in Belsey Mark IV antireflux surgery. Horbach, J.M., Masclee, A.A., Lamers, C.B., Gooszen, H.G. Gut (1994) [Pubmed]
  10. Congenital varicella-zoster virus infection and Barrett's esophagus. Ussery, X.T., Annunziato, P., Gershon, A.A., Reid, B.S., Lungu, O., Langston, C., Silverstein, S., Lee, K.K., Baker, C.J. J. Infect. Dis. (1998) [Pubmed]
  11. Laparoscopic fundoplication to enhance pulmonary function in children with severe reactive airway disease and gastroesophageal reflux disease. Rothenberg, S.S., Bratton, D., Larsen, G., Deterding, R., Milgrom, H., Brugman, S., Boguniewicz, M., Copenhaver, S., White, C., Wagener, J., Fan, L., Chang, J., Stathos, T. Surgical endoscopy. (1997) [Pubmed]
  12. A new antireflux procedure at the esophagogastric junction: experimental and clinical evaluation. Guarner, V., Degollade, J.R., Tore, N.M. Archives of surgery (Chicago, Ill. : 1960) (1975) [Pubmed]
  13. Cost effectiveness of medical versus surgical treatment in patients with severe or refractory gastroesophageal reflux disease in the Netherlands. Van Den Boom, G., Go, P.M., Hameeteman, W., Dallemagne, B., Ament, A.J. Scand. J. Gastroenterol. (1996) [Pubmed]
  14. Cisapride enhances the effect of partial posterior fundoplication on esophageal peristalsis in GERD patients with poor esophageal contractility. Wetscher, G.J., Glaser, K., Wieschemeyer, T., Gadenstätter, M., Klingler, P., Klingler, A., Hinder, R.A. Dig. Dis. Sci. (1998) [Pubmed]
  15. Early detection of CO2 pneumothorax with continuous spirometry during laparoscopic fundoplication. Mäkinen, M.T., Yli-Hankala, A., Kansanaho, M. Acta anaesthesiologica Scandinavica. (1995) [Pubmed]
  16. Long-term quantitative results following fundoplication and antroplasty for gastroesophageal reflux and delayed gastric emptying in children. Dunn, J.C., Lai, E.C., Webber, M.M., Ament, M.E., Fonkalsrud, E.W. Am. J. Surg. (1998) [Pubmed]
  17. Pneumothorax during laparoscopic fundoplication: diagnosis and treatment with positive end-expiratory pressure. Joris, J.L., Chiche, J.D., Lamy, M.L. Anesth. Analg. (1995) [Pubmed]
  18. Fractured heterotopic bone in a midline abdominal wound. Leis, V.M., Cotlar, A.M. Current surgery. (2003) [Pubmed]
  19. Gastroesophageal reflux and bronchial responsiveness: correlation and the effect of fundoplication. Kiljander, T.O., Salomaa, E.R., Hietanen, E.K., Ovaska, J., Helenius, H., Liippo, K. Respiration; international review of thoracic diseases. (2002) [Pubmed]
  20. Effect of Nissen fundoplication on the lower esophageal sphincter pressure of children with gastroesophageal reflux. Euler, A.R., Fonkalsrud, E.W., Ament, M.E. Gastroenterology (1977) [Pubmed]
  21. Effects of partial (Belsey Mark IV) and complete (Nissen) fundoplication on proximal gastric function and esophagogastric junction dynamics. Scheffer, R.C., Samsom, M., Hebbard, G.S., Gooszen, H.G. Am. J. Gastroenterol. (2006) [Pubmed]
  22. Problems associated with a Nissen fundoplication following tracheoesophageal fistula and esophageal atresia repair. Curci, M.R., Dibbins, A.W. Archives of surgery (Chicago, Ill. : 1960) (1988) [Pubmed]
  23. Increased serum amyloid A concentrations in morbid obesity decrease after gastric bypass. Gómez-Ambrosi, J., Salvador, J., Rotellar, F., Silva, C., Catalán, V., Rodríguez, A., Jesús Gil, M., Frühbeck, G. Obesity surgery : the official journal of the American Society for Bariatric Surgery and of the Obesity Surgery Society of Australia and New Zealand. (2006) [Pubmed]
  24. The efficacy of Thal fundoplication in the treatment of gastroesophageal reflux: the influence of central nervous system impairment. Tuggle, D.W., Tunell, W.P., Hoelzer, D.J., Smith, E.I. J. Pediatr. Surg. (1988) [Pubmed]
  25. Effect of intraoperative manipulation and anaesthesia on lower oesophageal sphincter function during fundoplication. Johnsson, F., Ireland, A.C., Jamieson, G.G., Dent, J., Holloway, R.H. The British journal of surgery. (1994) [Pubmed]
  26. Asthmatics with gastroesophageal reflux: long term results of a randomized trial of medical and surgical antireflux therapies. Sontag, S.J., O'Connell, S., Khandelwal, S., Greenlee, H., Schnell, T., Nemchausky, B., Chejfec, G., Miller, T., Seidel, J., Sonnenberg, A. Am. J. Gastroenterol. (2003) [Pubmed]
  27. Nissen-type fundoplication and its effects on the emetic reflex and gastric motility in the ferret. Richards, C.A., Carr, D., Spitz, L., Milla, P.J., Andrews, P.L. Neurogastroenterol. Motil. (2000) [Pubmed]
  28. Immune response after laparoscopic and conventional Nissen fundoplication. Perttilä, J., Salo, M., Ovaska, J., Grönroos, J., Lavonius, M., Katila, A., Lähteenmäki, M., Pulkki, K. The European journal of surgery = Acta chirurgica. (1999) [Pubmed]
  29. Experimental study of adhesion formation in open and laparoscopic fundoplication. Krähenbühl, L., Schäfer, M., Kuzinkovas, V., Renzulli, P., Baer, H.U., Büchler, M.W. The British journal of surgery. (1998) [Pubmed]
  30. Laparoscopic or open fundoplication? A complete cost analysis. Blomqvist, A.M., Lönroth, H., Dalenbäck, J., Lundell, L. Surgical endoscopy. (1998) [Pubmed]
  31. Reoperation after Nissen fundoplication in children with gastroesophageal reflux: experience with 130 patients. Dalla Vecchia, L.K., Grosfeld, J.L., West, K.W., Rescorla, F.J., Scherer, L.R., Engum, S.A. Ann. Surg. (1997) [Pubmed]
  32. Percutaneous gastrojejunostomy versus Nissen fundoplication for enteral feeding of the neurologically impaired child with gastroesophageal reflux. Albanese, C.T., Towbin, R.B., Ulman, I., Lewis, J., Smith, S.D. J. Pediatr. (1993) [Pubmed]
  33. Laparoscopic gastrostomy as an adjunctive procedure to laparoscopic fundoplication in children. Sampson, L.K., Georgeson, K.E., Winters, D.C. Surgical endoscopy. (1996) [Pubmed]
  34. Treatment of advanced gastroesophageal reflux disease with Collis gastroplasty and Belsey partial fundoplication. Ritter, M.P., Peters, J.H., DeMeester, T.R., Gadenstätter, M., Oberg, S., Fein, M., Hagen, J.A., Crookes, P.F., Bremner, C.G. Archives of surgery (Chicago, Ill. : 1960) (1998) [Pubmed]
WikiGenes - Universities