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MeSH Review

Liquid Crystals

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Disease relevance of Liquid Crystals


High impact information on Liquid Crystals

  • The discotic liquid crystal hexa-peri-hexabenzocoronene was used in combination with a perylene dye to produce thin films with vertically segregated perylene and hexabenzocoronene, with large interfacial surface area [3].
  • It was not possible to draw definite conclusions concerning the mechanism of action of the administered bile acids on the basis of cholesterol saturation or the presence of liquid crystals [4].
  • Human gallbladder mucin was associated with an increase in the number of liquid crystals after 4 days of incubation, which then decreased in number as solid cholesterol monohydrate crystals formed [5].
  • Concentrated (18-30%) solutions of Pluronic F127 are freely flowing liquids at low temperature (0-5 degrees C) but form gel-like, cubic liquid crystals of large, spherical micelles when warmed [6].
  • Residual quadrupole splittings for deuterons on perdeuterated alpha- and beta-D-mannose oriented in a potassium laurate liquid crystal have been measured [7].

Biological context of Liquid Crystals


Anatomical context of Liquid Crystals


Associations of Liquid Crystals with chemical compounds


Gene context of Liquid Crystals

  • With 11% (w/w) SP-B present, both bilayer systems display a continuous change from liquid crystal to gel with no evidence of two-phase coexistence near the transition [22].
  • The higher binding ability of the oriented RNase A over the randomly oriented RNase A was also apparent in the orientational behavior of nematic liquid crystals of 4-cyano-4'-pentylcyanobiphenyl (5CB) overlayed on these surfaces [23].
  • The binding of the ribonuclease inhibitor protein (RI) to RNase A on these surfaces was characterized by using ellipsometry and the orientational behavior of liquid crystals [23].
  • Recent advances in NIR-emitting materials, including liquid crystals, and in the control of luminescent properties in polymetallic assemblies are also presented [24].
  • Differential scanning calorimetry demonstrated that the physical state of the rHDL PL at 37 degrees C varied according to acyl chain length and degree of unsaturation; the FC efflux efficiencies for particles with PL in either the gel or liquid crystal states were determined [25].

Analytical, diagnostic and therapeutic context of Liquid Crystals


  1. Effects of fibric acid derivatives on biliary lipid composition. Palmer, R.H. Am. J. Med. (1987) [Pubmed]
  2. Ordering of quantum dots using genetically engineered viruses. Lee, S.W., Mao, C., Flynn, C.E., Belcher, A.M. Science (2002) [Pubmed]
  3. Self-organized discotic liquid crystals for high-efficiency organic photovoltaics. Schmidt-Mende, L., Fechtenkötter, A., Müllen, K., Moons, E., Friend, R.H., MacKenzie, J.D. Science (2001) [Pubmed]
  4. Bile acids substituted in the 6 position prevent cholesterol gallstone formation in the hamster. Cohen, B.I., Matoba, N., Mosbach, E.H., Ayyad, N., Hakam, K., Suh, S.O., McSherry, C.K. Gastroenterology (1990) [Pubmed]
  5. Human gallbladder mucin accelerates nucleation of cholesterol in artificial bile. Levy, P.F., Smith, B.F., LaMont, J.T. Gastroenterology (1984) [Pubmed]
  6. Electrophoresis in lyotropic polymer liquid crystals. Rill, R.L., Locke, B.R., Liu, Y., Van Winkle, D.H. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  7. Deuterium NMR as a structural probe for micelle-associated carbohydrates: D-mannose. Prestegard, J.H., Miner, V.W., Tyrell, P.M. Proc. Natl. Acad. Sci. U.S.A. (1983) [Pubmed]
  8. Liquid crystal thermography: quantitative studies of abnormalities in carpal tunnel syndrome. Meyers, S., Cros, D., Sherry, B., Vermeire, P. Neurology (1989) [Pubmed]
  9. Protein redistribution in model membranes: clearing of M13 coat protein from calcium-induced gel-phase regions in phosphatidylserine/phosphatidylcholine multilamellar vesicles. Florine, K.I., Feigenson, G.W. Biochemistry (1987) [Pubmed]
  10. Synthesis of 2-alkoxy-substituted thiophenes, 1,3-thiazoles, and related S-heterocycles via Lawesson's reagent-mediated cyclization under microwave irradiation: applications for liquid crystal synthesis. Kiryanov, A.A., Sampson, P., Seed, A.J. J. Org. Chem. (2001) [Pubmed]
  11. Transformation of macrophages into foam cells in vitro induced by cholesteryl oleate liquid crystals. Enomoto, M., Nakagami, K., Ohkuma, S., Takano, T. J. Biochem. (1987) [Pubmed]
  12. Molecular structure extracted from residual dipolar couplings: diphenylmethane dissolved in a nematic liquid crystal. Thaning, J., Stevensson, B., Maliniak, A. The Journal of chemical physics. (2005) [Pubmed]
  13. Effect of plasmid RP1 on phase changes in inner and outer membranes and lipopolysaccharide from Acinetobacter calcoaceticus: a Fourier transform infrared study. Loeffelholz, M.J., Rana, F., Modrzakowski, M.C., Blazyk, J. Biochemistry (1987) [Pubmed]
  14. Capillary electrophoretic separation of proteins and peptides using Pluronic liquid crystals and surface-modified capillaries. Miksík, I., Deyl, Z., Kasicka, V. J. Chromatogr. B Biomed. Sci. Appl. (2000) [Pubmed]
  15. Influence of bile salts on molecular interactions between sphingomyelin and cholesterol: relevance to bile formation and stability. van Erpecum, K.J., Carey, M.C. Biochim. Biophys. Acta (1997) [Pubmed]
  16. Effect of esterastin, an acid lipase inhibitor, on the free and esterified cholesterol contents of cultured aortic smooth muscle cells treated with LDL and cholesterol ester liquid crystals. Ecsedi, G.G., Amanuma, K., Imanaka, T., Aoyagi, T., Ohkuma, S., Takano, T. Biochem. Int. (1985) [Pubmed]
  17. Nature of the gel to liquid crystal transition of synthetic phosphatidylcholines. Albon, N., Sturtevant, J.M. Proc. Natl. Acad. Sci. U.S.A. (1978) [Pubmed]
  18. Cholesterol packing, crystallization and exchange properties in phosphatidylcholine vesicle systems. Phillips, M.C. Hepatology (1990) [Pubmed]
  19. Crystallization of phosphatidylserine bilayers induced by lithium. Hauser, H., Shipley, G.G. J. Biol. Chem. (1981) [Pubmed]
  20. Isotropic to nematic transition of aerosil-disordered liquid crystals. Caggioni, M., Roshi, A., Barjami, S., Mantegazza, F., Iannacchione, G.S., Bellini, T. Phys. Rev. Lett. (2004) [Pubmed]
  21. Universal nuclear spin relaxation and long-range order in nematics strongly confined in mass fractal silica gels. León, N., Korb, J.P., Bonalde, I., Levitz, P. Phys. Rev. Lett. (2004) [Pubmed]
  22. Pulmonary surfactant protein SP-B interacts similarly with dipalmitoylphosphatidylglycerol and dipalmitoylphosphatidylcholine in phosphatidylcholine/phosphatidylglycerol mixtures. Dico, A.S., Hancock, J., Morrow, M.R., Stewart, J., Harris, S., Keough, K.M. Biochemistry (1997) [Pubmed]
  23. Imaging the binding ability of proteins immobilized on surfaces with different orientations by using liquid crystals. Luk, Y.Y., Tingey, M.L., Dickson, K.A., Raines, R.T., Abbott, N.L. J. Am. Chem. Soc. (2004) [Pubmed]
  24. Taking advantage of luminescent lanthanide ions. Bünzli, J.C., Piguet, C. Chemical Society reviews. (2005) [Pubmed]
  25. The effect of high density lipoprotein phospholipid acyl chain composition on the efflux of cellular free cholesterol. Davidson, W.S., Gillotte, K.L., Lund-Katz, S., Johnson, W.J., Rothblat, G.H., Phillips, M.C. J. Biol. Chem. (1995) [Pubmed]
  26. Secondary structure of cyclosporine in a spray-dried liquid crystal by FTIR. Stevenson, C.L., Tan, M.M., Lechuga-Ballesteros, D. Journal of pharmaceutical sciences. (2003) [Pubmed]
  27. An antarctic psychrotrophic bacterium Halomonas sp. ANT-3b, growing on n-hexadecane, produces a new emulsyfying glycolipid. Pepi, M., Cesàro, A., Liut, G., Baldi, F. FEMS Microbiol. Ecol. (2005) [Pubmed]
  28. Permeation behavior of salbutamol sulfate through hydrophilic and hydrophobic membranes embedded by thermo-responsive cholesteryl oleyl carbonate. Lin, S.Y., Lin, Y.Y., Chen, K.S. Pharm. Res. (1996) [Pubmed]
  29. Three-dimensional adaptive optics ultrahigh-resolution optical coherence tomography using a liquid crystal spatial light modulator. Fernández, E.J., Povazay, B., Hermann, B., Unterhuber, A., Sattmann, H., Prieto, P.M., Leitgeb, R., Ahnelt, P., Artal, P., Drexler, W. Vision Res. (2005) [Pubmed]
  30. Adsorption of a cholesteric liquid crystal polyester on silver nanoparticles studied by surface-enhanced Raman scattering and micro Raman spectroscopy. Pérez-Méndez, M., Marsal-Berenguel, R., Sanchez-Cortes, S. Applied spectroscopy. (2004) [Pubmed]
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