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Chemical Compound Review

Maseptol     methyl 4-hydroxybenzoate

Synonyms: Methaben, Metoxyde, Tegosept, Metaben, Methylben, ...
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Disease relevance of Paraben


High impact information on Paraben


Chemical compound and disease context of Paraben


Biological context of Paraben


Anatomical context of Paraben


Associations of Paraben with other chemical compounds


Gene context of Paraben

  • Reduction of activity of cyanocobalamin (vitamin B12) due to degradation or interaction with methylparaben sodium was measured by UV spectrophotometry and microbial assay [22].

Analytical, diagnostic and therapeutic context of Paraben


  1. Enterobacter gergoviae and the prevalence of efflux in parabens resistance. Davin-Regli, A., Chollet, R., Bredin, J., Chevalier, J., Lepine, F., Pagès, J.M. J. Antimicrob. Chemother. (2006) [Pubmed]
  2. Resistance of a strain of Pseudomonas cepacia to esters of p-hydroxybenzoic acid. Close, J.A., Neilsen, P.A. Appl. Environ. Microbiol. (1976) [Pubmed]
  3. Oestrogenic activity of parabens in MCF7 human breast cancer cells. Byford, J.R., Shaw, L.E., Drew, M.G., Pope, G.S., Sauer, M.J., Darbre, P.D. J. Steroid Biochem. Mol. Biol. (2002) [Pubmed]
  4. Antibacterial properties of lidocaine. Wimberley, N., Willey, S., Sullivan, N., Bartlett, J.G. Chest (1979) [Pubmed]
  5. Allergic and systemic contact dermatitis to methylparaben. Sánchez-Pérez, J., Diez, M.B., Pérez, A.A., Jiménez, Y.D., Diez, G. Contact Derm. (2006) [Pubmed]
  6. X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Whittingham, J.L., Chaudhuri, S., Dodson, E.J., Moody, P.C., Dodson, G.G. Biochemistry (1995) [Pubmed]
  7. The effect of paraben preservatives on albumin binding of bilirubin. Rasmussen, L.F., Ahlfors, C.E., Wennberg, R.P. J. Pediatr. (1976) [Pubmed]
  8. Morphometric analysis of mice uteri treated with the preservatives methyl, ethyl, propyl, and butylparaben. Lemini, C., Hernández, A., Jaimez, R., Franco, Y., Avila, M.E., Castell, A. Toxicology and industrial health. (2004) [Pubmed]
  9. Comparison of the global gene expression profiles produced by methylparaben, n-butylparaben and 17beta-oestradiol in MCF7 human breast cancer cells. Pugazhendhi, D., Sadler, A.J., Darbre, P.D. Journal of applied toxicology : JAT (2007) [Pubmed]
  10. Does the use of lidocaine affect the culture of percutaneous bone biopsy specimens obtained to diagnose osteomyelitis? An in vitro and in vivo study. Schweitzer, M.E., Deely, D.M., Beavis, K., Gannon, F. AJR. American journal of roentgenology. (1995) [Pubmed]
  11. Inhibition of Listeria monocytogenes and Salmonella enteriditis by combinations of plant oils and derivatives of benzoic acid: the development of synergistic antimicrobial combinations. Fyfe, L., Armstrong, F., Stewart, J. Int. J. Antimicrob. Agents (1997) [Pubmed]
  12. Preventing sexual transmission of HIV: anti-HIV bioregulatory and homeostatic components of commercial sexual lubricants. Nguyen, D., Lee, H., Poast, J., Cloyd, M.W., Baron, S. J. Biol. Regul. Homeost. Agents (2004) [Pubmed]
  13. Determination in plasma of angiotensin-converting enzyme inhibitor by inhibitor-binding assay. Shioya, H., Shimojo, M., Kawahara, Y. J. Chromatogr. (1991) [Pubmed]
  14. Methylparaben potentiates UV-induced damage of skin keratinocytes. Handa, O., Kokura, S., Adachi, S., Takagi, T., Naito, Y., Tanigawa, T., Yoshida, N., Yoshikawa, T. Toxicology (2006) [Pubmed]
  15. Morphological effects of subarachnoid methylparaben on rabbit spinal cord. Adams, H.J., Mastri, A.R., Charron, D. Pharmacological research communications. (1977) [Pubmed]
  16. Adsorption of esters of p-hydroxybenzoic acid by filter membranes: mechanism and effect of formulation and processing parameters. Bin, T., McCrosky, L., Kulshreshtha, A.K., Hem, S.L. Pharmaceutical development and technology. (2000) [Pubmed]
  17. Comparison of equations describing band broadening in high-performance liquid chromatography. Kirkup, L., Foot, M., Mulholland, M. Journal of chromatography. A. (2004) [Pubmed]
  18. Role of oxidants, eicosanoids, and neutrophils in amphotericin B lung injury in rats. McDonnell, T.J., Chang, S.W., Westcott, J.Y., Voelkel, N.F. J. Appl. Physiol. (1988) [Pubmed]
  19. A novel gradient HPLC method for simultaneous determination of ranitidine, methylparaben and propylparaben in oral liquid pharmaceutical formulation. Kokoletsi, M.X., Kafkala, S., Tsiaganis, M. Journal of pharmaceutical and biomedical analysis. (2005) [Pubmed]
  20. Influence of methylparaben as a solid-state plasticizer on the physicochemical properties of Eudragit RS PO hot-melt extrudates. Wu, C., McGinity, J.W. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V. (2003) [Pubmed]
  21. Type IV allergy to amide-type local anesthetics. Klein, C.E., Gall, H. Contact Derm. (1991) [Pubmed]
  22. Reduction of activity of cyanocobalamin in the presence of methylparaben sodium at autoclave temperature. Yazdany, S., Badii, F. Journal of pharmaceutical sciences. (1976) [Pubmed]
  23. Urinary excretion of methylparaben and its metabolites in preterm infants. Hindmarsh, K.W., John, E., Asali, L.A., French, J.N., Williams, G.L., McBride, W.G. Journal of pharmaceutical sciences. (1983) [Pubmed]
  24. Methylparaben and propylparaben do not alter cerebral blood flow in humans. Gelb, A.W., Gignac, E., Manninen, P.H., Farrar, J.K., Lee, D.H. Canadian journal of anaesthesia = Journal canadien d'anesthésie. (1992) [Pubmed]
  25. Understanding allergic reactions to local anesthetics. Eggleston, S.T., Lush, L.W. The Annals of pharmacotherapy. (1996) [Pubmed]
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