The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

Mas-AKH     N-[(1S)-1-[[(1S,2R)-1-[[(1S)- 1-[[(1S,2R)-1...

Synonyms: AKH-M, H-AKH, AC1L3XCS, AC1Q6OZU, AR-1G9358, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of adipokinetic hormone

 

Psychiatry related information on adipokinetic hormone

 

High impact information on adipokinetic hormone

 

Biological context of adipokinetic hormone

 

Anatomical context of adipokinetic hormone

 

Associations of adipokinetic hormone with other chemical compounds

 

Gene context of adipokinetic hormone

  • A member of the RPCH/AKH (red-pigment-concentrating hormone/adipokinetic hormone) family of arthropod neuropeptides was identified in the fruitfly Drosophila melanogaster, and its structure was determined by automated Edman degradation and m.s. using fast-atom-bombardment ionization and a tandem hybrid instrument capable of high sensitivity [21].
  • The cytosolic fraction of homogenates from the free-living soil nematode Caenorhabditis elegans is capable of metabolizing the insect neuropeptide adipokinetic hormone, a decapeptide blocked at the N-terminus by a pGlu residue [22].
  • The bioactive peptides adipokinetic hormone and substance P decrease the apparent aminopeptidase activities of each extract suggesting that the peptides compete with the Ala-pNA as substrates [23].
  • In larvae, the LNCs express high levels of a myoregulatory peptide, cardioacceleratory peptide 2 (CAP2) [24].
  • Previous results from this laboratory suggested that the hydrolysis of stored triacylglycerol to sn-2-monoacylglycerol followed by the stereospecific acylation of sn-2-monoacylglycerol catalyzed by a monoacylglycerol-acyltransferase (MGAT) could be the major route of AKH-stimulated sn-1,2-diacylglycerol synthesis [25].
 

Analytical, diagnostic and therapeutic context of adipokinetic hormone

References

  1. Differential receptor activation by cockroach adipokinetic hormones produces differential effects on ion currents, neuronal activity, and locomotion. Wicher, D., Agricola, H.J., Söhler, S., Gundel, M., Heinemann, S.H., Wollweber, L., Stengl, M., Derst, C. J. Neurophysiol. (2006) [Pubmed]
  2. The use of decapitated insects to study lipid mobilization in adult Manduca sexta: effects of adipokinetic hormone and trehalose on fat body lipase activity. Arrese, E.L., Rojas-Rivas, B.I., Wells, M.A. Insect Biochem. Mol. Biol. (1996) [Pubmed]
  3. Adipokinetic hormone stimulates neurones in the insect central nervous system. Milde, J.J., Ziegler, R., Wallstein, M. J. Exp. Biol. (1995) [Pubmed]
  4. Synthesis of a homodimer neurohormone precursor of locust adipokinetic hormone studied by in vitro translation and cDNA cloning. Schulz-Aellen, M.F., Roulet, E., Fischer-Lougheed, J., O'Shea, M. Neuron (1989) [Pubmed]
  5. Activation of the lipid droplet controls the rate of lipolysis of triglycerides in the insect fat body. Patel, R.T., Soulages, J.L., Hariharasundaram, B., Arrese, E.L. J. Biol. Chem. (2005) [Pubmed]
  6. An insect lipid transfer particle promotes lipid loading from fat body to lipoprotein. Van Heusden, M.C., Law, J.H. J. Biol. Chem. (1989) [Pubmed]
  7. Adipokinetic hormone gene sequence from Manduca sexta. Bradfield, J.Y., Keeley, L.L. J. Biol. Chem. (1989) [Pubmed]
  8. The role of apolipophorin III in in vivo lipoprotein interconversions in adult Manduca sexta. Wells, M.A., Ryan, R.O., Kawooya, J.K., Law, J.H. J. Biol. Chem. (1987) [Pubmed]
  9. Peptidergic control of the corpus cardiacum-corpora allata complex of locusts. Veelaert, D., Schoofs, L., De Loof, A. Int. Rev. Cytol. (1998) [Pubmed]
  10. Neuropeptide-degrading endopeptidase activity of locust (Schistocerca gregaria) synaptic membranes. Isaac, R.E. Biochem. J. (1988) [Pubmed]
  11. Adipokinetic hormone-induced lipolysis in the fat body of an insect, Manduca sexta: synthesis of sn-1,2-diacylglycerols. Arrese, E.L., Wells, M.A. J. Lipid Res. (1997) [Pubmed]
  12. Hemolymph sugar homeostasis and starvation-induced hyperactivity affected by genetic manipulations of the adipokinetic hormone-encoding gene in Drosophila melanogaster. Lee, G., Park, J.H. Genetics (2004) [Pubmed]
  13. A strategy for solubilizing delipidated apolipoprotein with lysophosphatidylcholine and reconstitution with phosphatidylcholine. Kawooya, J.K., Wells, M.A., Law, J.H. Biochemistry (1989) [Pubmed]
  14. Immunolocalization of a tachykinin-receptor-like protein in the central nervous system of Locusta migratoria migratorioides and neobellieria bullata. Veelaert, D., Oonk, H.B., Vanden Eynde, G., Torfs, H., Meloen, R.H., Schoofs, L., Parmentier, M., De Loof, A., Vanden Broeck, J. J. Comp. Neurol. (1999) [Pubmed]
  15. Identification and characterization of adipokinetic hormone (Locusta migratoria)-like immunoreactivity in the human cerebrospinal fluid. Suzuki, H., Sato, S., Tsuchiya, T., Suzuki, Y., Muramatsu, H., Ishihara, N., Shimoda, S. Biochem. Biophys. Res. Commun. (1989) [Pubmed]
  16. Primary role of adipokinetic hormone in the formation of low density lipophorin in locusts. Lum, P.Y., Chino, H. J. Lipid Res. (1990) [Pubmed]
  17. Calcium and cAMP are second messengers in the adipokinetic hormone-induced lipolysis of triacylglycerols in Manduca sexta fat body. Arrese, E.L., Flowers, M.T., Gazard, J.L., Wells, M.A. J. Lipid Res. (1999) [Pubmed]
  18. Octopamine and cyclic AMP mediate release of adipokinetic hormone I and II from isolated locust neuroendocrine tissue. Pannabecker, T., Orchard, I. Mol. Cell. Endocrinol. (1986) [Pubmed]
  19. Characterization of the adipokinetic hormone receptor form the fat body of Manduca sexta. Ziegler, R., Jasensky, R.D., Morimoto, H. Regul. Pept. (1995) [Pubmed]
  20. Amino acid sequence of Manduca sexta adipokinetic hormone elucidated by combined fast atom bombardment (FAB)/tandem mass spectrometry. Ziegler, R., Eckart, K., Schwarz, H., Keller, R. Biochem. Biophys. Res. Commun. (1985) [Pubmed]
  21. The fruitfly Drosophila melanogaster contains a novel charged adipokinetic-hormone-family peptide. Schaffer, M.H., Noyes, B.E., Slaughter, C.A., Thorne, G.C., Gaskell, S.J. Biochem. J. (1990) [Pubmed]
  22. In vitro metabolism of an insect neuropeptide by homogenates of the nematode Caenorhabditis elegans. Masler, E.P. J. Helminthol. (2003) [Pubmed]
  23. Aminopeptidases in Caenorhabditis elegans and Panagrellus redivivus: detection using peptide and non-peptide substrates. Masler, E.P. J. Helminthol. (2002) [Pubmed]
  24. Hormonal control of transmitter plasticity in insect peptidergic neurons. I. Steroid regulation of the decline in cardioacceleratory peptide 2 (CAP2) expression. Loi, P.K., Tublitz, N.J. J. Exp. Biol. (1993) [Pubmed]
  25. Synthesis of sn-1,2-diacylglycerols by monoacylglycerol acyltransferase from Manduca sexta fat body. Arrese, E.L., Rojas-Rivas, B.I., Wells, M.A. Arch. Insect Biochem. Physiol. (1996) [Pubmed]
  26. Postembryonic proliferation of neuroendocrine cells expressing adipokinetic hormone peptides in the corpora cardiaca of the locust. Kirschenbaum, S.R., O'Shea, M. Development (1993) [Pubmed]
  27. Immunological, biochemical and physiological analyses of cardioacceleratory peptide 2 (CAP2) activity in the embryo of the tobacco hawkmoth Manduca sexta. Broadie, K.S., Sylwester, A.W., Bate, M., Tublitz, N.J. Development (1990) [Pubmed]
  28. A novel adipokinetic octapeptide found in the damselflies Pseudagrion inconspicuum and Ischnura senegalensis. Janssens, M.P., Kellner, R., Gde, G. Biochem. J. (1994) [Pubmed]
  29. Isolation and primary structure of a peptide from the corpora cardiaca of Heliothis zea with adipokinetic activity. Jaffe, H., Raina, A.K., Riley, C.T., Fraser, B.A., Holman, G.M., Wagner, R.M., Ridgway, R.L., Hayes, D.K. Biochem. Biophys. Res. Commun. (1986) [Pubmed]
 
WikiGenes - Universities