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Chemical Compound Review

Mehp     2-(2- ethylhexoxycarbonyl)benzoic acid

Synonyms: MEHP-d4, BAR 1, SureCN472689, CCRIS 1742, AG-F-54460, ...
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Disease relevance of MONO-2-ETHYLHEXYL PHTHALATE


High impact information on MONO-2-ETHYLHEXYL PHTHALATE


Chemical compound and disease context of MONO-2-ETHYLHEXYL PHTHALATE


Biological context of MONO-2-ETHYLHEXYL PHTHALATE


Anatomical context of MONO-2-ETHYLHEXYL PHTHALATE


Associations of MONO-2-ETHYLHEXYL PHTHALATE with other chemical compounds




Analytical, diagnostic and therapeutic context of MONO-2-ETHYLHEXYL PHTHALATE


  1. Hypotension and cardiac arrest in rats after infusion of mono(2-ethylhexyl) phthalate (MEHP), a contaminant of stored blood. Rock, G., Labow, R.S., Franklin, C., Burnett, R., Tocchi, M. N. Engl. J. Med. (1987) [Pubmed]
  2. Perioperative exposure to plasticizers in patients undergoing cardiopulmonary bypass. Barry, Y.A., Labow, R.S., Keon, W.J., Tocchi, M., Rock, G. J. Thorac. Cardiovasc. Surg. (1989) [Pubmed]
  3. Uraemic pruritus and exposure to di(2-ethylhexyl) phthalate (DEHP) in haemodialysis patients. Mettang, T., Thomas, S., Kiefer, T., Fischer, F.P., Kuhlmann, U., Wodarz, R., Rettenmeier, A.W. Nephrol. Dial. Transplant. (1996) [Pubmed]
  4. The acute effects of mono(2-ethylhexyl)phthalate (MEHP) on testes of prepubertal Wistar rats. Dalgaard, M., Nellemann, C., Lam, H.R., Sørensen, I.K., Ladefoged, O. Toxicol. Lett. (2001) [Pubmed]
  5. Evaluation of di-(2-ethylhexyl)phthalate and its major metabolites in the Ames test and L5178Y mouse lymphoma mutagenicity assay. Kirby, P.E., Pizzarello, R.F., Lawlor, T.E., Haworth, S.R., Hodgson, J.R. Environmental mutagenesis. (1983) [Pubmed]
  6. Use of primary cultures of human hepatocytes in toxicology studies. Butterworth, B.E., Smith-Oliver, T., Earle, L., Loury, D.J., White, R.D., Doolittle, D.J., Working, P.K., Cattley, R.C., Jirtle, R., Michalopoulos, G. Cancer Res. (1989) [Pubmed]
  7. Environmental and endogenous peroxisome proliferator-activated receptor gamma agonists induce bone marrow B cell growth arrest and apoptosis: interactions between mono(2-ethylhexyl)phthalate, 9-cis-retinoic acid, and 15-deoxy-Delta12,14-prostaglandin J2. Schlezinger, J.J., Howard, G.J., Hurst, C.H., Emberley, J.K., Waxman, D.J., Webster, T., Sherr, D.H. J. Immunol. (2004) [Pubmed]
  8. Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Richburg, J.H., Nañez, A., Williams, L.R., Embree, M.E., Boekelheide, K. Endocrinology (2000) [Pubmed]
  9. Inhibition of intercellular communication of rat hepatocytes by nafenopin: involvement of protein kinase C. Leibold, E., Greim, H., Schwarz, L.R. Carcinogenesis (1994) [Pubmed]
  10. Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age. Main, K.M., Mortensen, G.K., Kaleva, M.M., Boisen, K.A., Damgaard, I.N., Chellakooty, M., Schmidt, I.M., Suomi, A.M., Virtanen, H.E., Petersen, D.V., Andersson, A.M., Toppari, J., Skakkebaek, N.E. Environ. Health Perspect. (2006) [Pubmed]
  11. Mutagenicity evaluation of phthalic acid esters and metabolites in Salmonella typhimurium cultures. Agarwal, D.K., Lawrence, W.H., Nunez, L.J., Autian, J. Journal of toxicology and environmental health. (1985) [Pubmed]
  12. Studies on the genetic effects of phthalic acid esters on cells in culture. Phillips, B.J., Anderson, D., Gangolli, S.D. Environ. Health Perspect. (1986) [Pubmed]
  13. In utero exposure to di-(2-ethylhexyl)phthalate and duration of human pregnancy. Latini, G., De Felice, C., Presta, G., Del Vecchio, A., Paris, I., Ruggieri, F., Mazzeo, P. Environ. Health Perspect. (2003) [Pubmed]
  14. Expression of stress inducible protein 1 (Stip1) in the mouse testis. Mizrak, S.C., Bogerd, J., Lopez-Casas, P.P., Párraga, M., Del Mazo, J., de Rooij, D.G. Mol. Reprod. Dev. (2006) [Pubmed]
  15. Exposure of patients to phthalates from polyvinyl chloride tubes and bags during dialysis. Nässberger, L., Arbin, A., Ostelius, J. Nephron (1987) [Pubmed]
  16. Mechanisms of phthalate ester toxicity in the female reproductive system. Lovekamp-Swan, T., Davis, B.J. Environ. Health Perspect. (2003) [Pubmed]
  17. Effect of mono-(2-ethylhexyl)phthalate on follicle-stimulating hormone responsiveness of cultured rat Sertoli cells. Lloyd, S.C., Foster, P.M. Toxicol. Appl. Pharmacol. (1988) [Pubmed]
  18. Exposure to phthalates in neonatal intensive care unit infants: urinary concentrations of monoesters and oxidative metabolites. Weuve, J., Sánchez, B.N., Calafat, A.M., Schettler, T., Green, R.A., Hu, H., Hauser, R. Environ. Health Perspect. (2006) [Pubmed]
  19. Phthalate ester effects on rat Sertoli cell function in vitro: effects of phthalate side chain and age of animal. Heindel, J.J., Powell, C.J. Toxicol. Appl. Pharmacol. (1992) [Pubmed]
  20. Fas- or FasL-deficient mice display an increased sensitivity to nitrobenzene-induced testicular germ cell apoptosis. Richburg, J.H., Nañez, A. Toxicol. Lett. (2003) [Pubmed]
  21. Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): species differences and possible mechanisms. Elcombe, C.R., Mitchell, A.M. Environ. Health Perspect. (1986) [Pubmed]
  22. The production of lactate and pyruvate as sensitive indices of altered rat Sertoli cell function in vitro following the addition of various testicular toxicants. Williams, J., Foster, P.M. Toxicol. Appl. Pharmacol. (1988) [Pubmed]
  23. Structure-activity relationships for induction of peroxisomal enzyme activities by phthalate monoesters in primary rat hepatocyte cultures. Lake, B.G., Gray, T.J., Lewis, D.F., Beamand, J.A., Hodder, K.D., Purchase, R., Gangolli, S.D. Toxicology and industrial health. (1987) [Pubmed]
  24. Mono(2-ethylhexyl)phthalate exhibits genotoxic effects in human lymphocytes and mucosal cells of the upper aerodigestive tract in the comet assay. Kleinsasser, N.H., Harréus, U.A., Kastenbauer, E.R., Wallner, B.C., Sassen, A.W., Staudenmaier, R., Rettenmeier, A.W. Toxicol. Lett. (2004) [Pubmed]
  25. Cytogenetic evaluation of di-(2-ethylhexyl)phthalate and its major metabolites in Fischer 344 rats. Putman, D.L., Moore, W.A., Schechtman, L.M., Hodgson, J.R. Environmental mutagenesis. (1983) [Pubmed]
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