Chemical Compound Review:
AC1MDQME (2R,3R,4S,5R)-2-amino- 3,4,5,6-tetrahydroxy...
Synonyms:
AG-H-00305, CHEBI:60313, CTK5E1468, KB-206459, AKOS006281393, ...
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- PGE1 protection against apoptosis induced by D-galactosamine is not related to the modulation of intracellular free radical production in primary culture of rat hepatocytes. Quintero, A., Pedraza, C.A., Siendones, E., Kamal ElSaid, A.M., Colell, A., García-Ruiz, C., Montero, J.L., De la Mata, M., Fernández-Checa, J.C., Miño, G., Muntané, J. Free Radic. Res. (2002)
- PGE1-induced NO reduces apoptosis by D-galactosamine through attenuation of NF-kappaB and NOS-2 expression in rat hepatocytes. Siendones, E., Fouad, D., Díaz-Guerra, M.J., de la Mata, M., Boscá, L., Muntané, J. Hepatology (2004)
- TNF-alpha but not IL-1alpha is correlated with PGE1-dependent protection against acute D-galactosamine-induced liver injury. Muntané, J., Montero, J.L., Lozano, J.M., Miranda-Vizuete, A., de La Mata, M., Miño, G. Can. J. Gastroenterol. (2000)
- Involvement of 26-kDa cell-associated TNF-alpha in experimental hepatitis and exacerbation of liver injury with a matrix metalloproteinase inhibitor. Solorzano, C.C., Ksontini, R., Pruitt, J.H., Hess, P.J., Edwards, P.D., Kaibara, A., Abouhamze, A., Auffenberg, T., Galardy, R.E., Vauthey, J.N., Copeland, E.M., Edwards, C.K., Lauwers, G.Y., Clare-Salzler, M., MacKay, S.L., Moldawer, L.L., Lazarus, D.D. J. Immunol. (1997)
- Hepatoprotective effect of taxiresinol and (7'R)-7'-hydroxylariciresinol on D-galactosamine and lipopolysaccharide-induced liver injury in mice. Nguyen, N.T., Banskota, A.H., Tezuka, Y., Le Tran, Q., Nobukawa, T., Kurashige, Y., Sasahara, M., Kadota, S. Planta Med. (2004)
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- Protective effect of wogonin on endotoxin-induced lethal shock in D-galactosamine-sensitized mice. Van Dien, M., Takahashi, K., Mu, M.M., Koide, N., Sugiyama, T., Mori, I., Yoshida, T., Yokochi, T. Microbiol. Immunol. (2001)
- Inhibitory effect and action mechanism of sesquiterpenes from Zedoariae Rhizoma on D-galactosamine/lipopolysaccharide-induced liver injury. Matsuda, H., Ninomiya, K., Morikawa, T., Yoshikawa, M. Bioorg. Med. Chem. Lett. (1998)
- Immunomodulatory activity of TNF-alpha during acute liver injury induced by D-galactosamine and its protection by PGE1 in rats. Lozano, J.M., Padillo, J., Montero, J.L., Peña, J., De la Mata, M., Muntané, J. Int. Immunopharmacol. (2003)
- TNF-alpha dependent production of inducible nitric oxide is involved in PGE(1) protection against acute liver injury. Muntané, J., Rodríguez, F.J., Segado, O., Quintero, A., Lozano, J.M., Siendones, E., Pedraza, C.A., Delgado, M., O'Valle, F., García, R., Montero, J.L., De La Mata, M., Miño, G. Gut (2000)
- Inhibitory effect of tetrahydroswertianolin on tumor necrosis factor-alpha-dependent hepatic apoptosis in mice. Hase, K., Xiong, Q., Basnet, P., Namba, T., Kadota, S. Biochem. Pharmacol. (1999)
- Xanthine oxidase-derived reactive oxygen species contribute to the development of D-galactosamine-induced liver injury in rats. Ohta, Y., Matsura, T., Kitagawa, A., Tokunaga, K., Yamada, K. Free Radic. Res. (2007)
- Hepatoprotective principles from the flowers of Tilia argentea (linden): structure requirements of tiliroside and mechanisms of action. Matsuda, H., Ninomiya, K., Shimoda, H., Yoshikawa, M. Bioorg. Med. Chem. (2002)
- CpG-DNA upregulates the major acute-phase proteins SAA and SAP. Schmidt, U., Wagner, H., Miethke, T. Cell. Microbiol. (1999)
- Gene transfer with IL-4 and IL-13 improves survival in lethal endotoxemia in the mouse and ameliorates peritoneal macrophages immune competence. Baumhofer, J.M., Beinhauer, B.G., Wang, J.E., Brandmeier, H., Geissler, K., Losert, U., Philip, R., Aversa, G., Rogy, M.A. Eur. J. Immunol. (1998)
- Protection against liver injury by PGE1 or anti-TNF-alpha is associated with a reduction of TNF-R1 expression in hepatocytes. Lozano, J.M., Collado, J.A., Medina, T., Muntané, J. Scand. J. Gastroenterol. (2003)
- The enhancing action of D-galactosamine on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells. Morikawa, A., Koide, N., Sugiyama, T., Mu, M.M., Hassan, F., Islam, S., Ito, H., Mori, I., Yoshida, T., Yokochi, T. FEMS Immunol. Med. Microbiol. (2004)
- Adenovirus-mediated hepatocyte growth factor gene transfer prevents lethal liver failure in rats. Nomi, T., Shiota, G., Isono, M., Sato, K., Kawasaki, H. Biochem. Biophys. Res. Commun. (2000)
- D-galactosamine-induced mouse hepatic apoptosis: possible involvement with tumor necrosis factor, but not with caspase-3 activity. Itokazu, Y., Segawa, Y., Inoue, N., Omata, T. Biol. Pharm. Bull. (1999)