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Chemical Compound Review

Sencorex     4-amino-3-methylsulfanyl-6- tert-butyl-1,2...

Synonyms: Lexone, METRIBUZIN, Sencor, Senkor, Zenkor, ...
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Disease relevance of Lexone


High impact information on Lexone


Biological context of Lexone


Anatomical context of Lexone


Associations of Lexone with other chemical compounds


Gene context of Lexone

  • A thermospray liquid chromatographic-mass spectrometric (TSP LC-MS) method has been developed for the analysis of the herbicide metribuzin and its three major metabolites in plant tissue [22].
  • In the enclosure study, indirect effects of metribuzin on invertebrate populations were observed at an exposure concentration that was approximately 20 times lower than the corresponding HC5 value based on lab toxicity data for aquatic invertebrates [17].
  • Thus the detrimental effects of metribuzin application to lentils were mainly due to direct effects on the plant, which resulted in indirect effects on nodulation and nitrogen fixation [2].
  • In the case of White Lady, Százszorszép and Kánkán N concentration and uptake increase significantly because of SENCOR 70 WG [23].
  • Nevertheless, in treatments in which the S10 metabolic mix was added, the SCE frequencies were significantly different to the control, although a concentration-response relationship was only observed with metribuzin [13].

Analytical, diagnostic and therapeutic context of Lexone

  • Metribuzin resistance in photoautotrophic Chenopodium rubrum cell cultures. Characterization of double and triple mutations in the psbA gene [5].
  • The electrochemical behavior of the herbicide metribuzin (4-amino-6-tert-butyl-4,5-dihydro-3-methylthio-1,2,4-triazin-5-one) at mercury electrodes was studied in aqueous solutions by direct current (DC) and tast polarography, differential pulse (DPV) and cyclic voltammetry (CV), and controlled-potential coulometry [24].
  • Determinations of the active ingredient in technical and formulated metribuzin were compared by gas-liquid chromatography (GLC) using various solvents, infrared (IR) spectrophotometry, and high-pressure liquid chromatography (HPLC) [25].


  1. On the way to cyanobacterial blooms: Impact of the herbicide metribuzin on the competition between a green alga (Scenedesmus) and a cyanobacterium (Microcystis). Lürling, M., Roessink, I. Chemosphere (2006) [Pubmed]
  2. Influence of metribuzin on the Rhizobium leguminosarum--lentil (Lens culinaris) symbiosis. Sprout, S.L., Nelson, L.M., Germida, J.J. Can. J. Microbiol. (1992) [Pubmed]
  3. Effects of exposure duration of herbicides on natural stream periphyton communities and recovery. Gustavson, K., Møhlenberg, F., Schlüter, L. Arch. Environ. Contam. Toxicol. (2003) [Pubmed]
  4. Comparison of two screening bioassays, based on the frog sciatic nerve and yeast cells, for the assessment of herbicide toxicity. Papaefthimiou, C., Cabral, M.d.e. .G., Mixailidou, C., Viegas, C.A., Sá-Correia, I., Theophilidis, G. Environ. Toxicol. Chem. (2004) [Pubmed]
  5. Metribuzin resistance in photoautotrophic Chenopodium rubrum cell cultures. Characterization of double and triple mutations in the psbA gene. Schwenger-Erger, C., Thiemann, J., Barz, W., Johanningmeier, U., Naber, D. FEBS Lett. (1993) [Pubmed]
  6. Metribuzin degradation by membrane anodic Fenton treatment and its interaction with ferric ion. Wang, Q., Scherer, E.M., Lemley, A.T. Environ. Sci. Technol. (2004) [Pubmed]
  7. Molecularly imprinted polymer membranes for substance-selective solid-phase extraction from water by surface photo-grafting polymerization. Sergeyev, T.A., Matuschewski, H., Piletsky, S.A., Bendig, J., Schedler, U., Ulbricht, M. Journal of chromatography. A. (2001) [Pubmed]
  8. UV-B radiation induced exchange of the D1 reaction centre subunits produced from the psbA2 and psbA3 genes in the Cyanobacterium synechocystis sp. PCC 6803. Vass, I., Kirilovsky, D., Perewoska, I., Máté, Z., Nagy, F., Etienne, A.L. Eur. J. Biochem. (2000) [Pubmed]
  9. Determination of triazine herbicides in foods with liquid chromatography mass spectrometry. Okihashi, M., Akutsu, K., Obana, H., Hori, S. The Analyst. (2000) [Pubmed]
  10. Fate and effects of the triazinone herbicide metribuzin in experimental pond mesocosms. Fairchild, J.F., Sappington, L.C. Arch. Environ. Contam. Toxicol. (2002) [Pubmed]
  11. The F684/F735 chlorophyll fluorescence ratio: a potential tool for rapid detection and determination of herbicide phytotoxicity in algae. Eullaffroy, P., Vernet, G. Water Res. (2003) [Pubmed]
  12. Bioavailability in rats of bound pesticide residues from tolerant or susceptible varieties of soybean and canola treated with metribuzin or atrazine. Mathew, R., Kacew, S., Khan, S.U. Chemosphere (1998) [Pubmed]
  13. Promutagen activation of triazine herbicides metribuzin and ametryn through Vicia faba metabolism inducing sister chromatid exchanges in human lymphocytes in vitro and in V. faba root tip meristems. Flores-Maya, S., Gómez-Arroyo, S., Calderón-Segura, M.E., Villalobos-Pietrini, R., Waliszewski, S.M., de la Cruz, L.G. Toxicology in vitro : an international journal published in association with BIBRA. (2005) [Pubmed]
  14. Fatty acid alteration of plastidic and extra-plastidic membrane lipids in metribuzin-resistant photoautotrophic Chenopodium rubrum cells as compared to wild-type cells. Schwenger-Erger, C., Barz, W., Weber, N. Z. Naturforsch., C, J. Biosci. (2001) [Pubmed]
  15. Glycoprotein metabolism in the guinea-pig gastric mucosa in chronic metribuzin poisoning. Zwierz, K., Tomaszewski, J., Rózański, A., Kreczko, S. Acta biologica Academiae Scientiarum Hungaricae. (1981) [Pubmed]
  16. Liver histology in chronic metribuzin poisoning of the guinea-pig. Tomaszewski, J., Zwierz, K., Musiatowicz, B., Jezyna, C. Acta. Biol. Hung. (1986) [Pubmed]
  17. Comparing aquatic risk assessment methods for the photosynthesis-inhibiting herbicides metribuzin and metamitron. Brock, T.C., Crum, S.J., Deneer, J.W., Heimbach, F., Roijackers, R.M., Sinkeldam, J.A. Environ. Pollut. (2004) [Pubmed]
  18. The binary treatment of aqueous metribuzin using anodic fenton treatment and biodegradation. Scherer, E.M., Wang, Q.Q., Hay, A.G., Lemley, A.T. Arch. Environ. Contam. Toxicol. (2004) [Pubmed]
  19. Effect of airborne bromoxynil-octanoate and metribuzin on non-target plants. Follak, S., Hurle, K. Environ. Pollut. (2003) [Pubmed]
  20. Interactive effects of the fungicide chlorothalonil and the herbicide metribuzin towards the fungal pathogen Alternaria solani. Hill, T.L., Stratton, G.W. Bulletin of environmental contamination and toxicology. (1991) [Pubmed]
  21. Degradation of metribuzin in two soil types of Lebanon. Khoury, R., Coste, C.M., Kawar, N.S. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. (2006) [Pubmed]
  22. Thermospray liquid chromatographic-mass spectrometric method for the analysis of metribuzin and its metabolites. Parker, C.E., Geeson, A.V., Games, D.E., Ramsey, E.D., Abusteit, E.O., Corbin, F.T., Tomer, K.B. J. Chromatogr. (1988) [Pubmed]
  23. Investigation of the effect of soil herbicides on the growth and nutrient uptake of potato. Dobozi, M., Lehoczky, E., Horváth, S. Communications in agricultural and applied biological sciences. (2003) [Pubmed]
  24. Electrochemical behavior and voltammetric determination of the herbicide metribuzin at mercury electrodes. Skopalová, J., Lemr, K., Kotoucek, M., Cáp, L., Barták, P. Fresenius' journal of analytical chemistry. (2001) [Pubmed]
  25. Comparison of analytical methods for metribuzin. Betker, W.R., Smead, C.F., Evans, R.T. Journal - Association of Official Analytical Chemists. (1976) [Pubmed]
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