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Chemical Compound Review

PubChem8163     4-nitrobenzaldehyde

Synonyms: CPD-703, AGN-PC-007OFU, CHEMBL164236, NSC-6103, ACMC-1B0H8, ...
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Disease relevance of p-Nitrobenzaldehyde


High impact information on p-Nitrobenzaldehyde


Biological context of p-Nitrobenzaldehyde


Anatomical context of p-Nitrobenzaldehyde


Associations of p-Nitrobenzaldehyde with other chemical compounds


Gene context of p-Nitrobenzaldehyde

  • AHR-A2 exhibited a defined specificity toward p-nitrobenzaldehyde as substrate, whereas the other enzymes exhibited broad specificities toward various aliphatic, aromatic, and monosaccharide aldehydes [20].
  • This indicated that M79175 was the most effective inhibitor tested of aldose reductase with 4NB in vitro [21].
  • In untreated mice, carbonyl reductase activity towards 15KD-PGF2 alpha was not detected, whereas the activities towards PNAP and PNBA were detected, which activities were lower than those in rats and hamsters [22].
  • This radiotracer has been synthesized using nucleophilic displacement of the activated nitro group of p-nitrobenzaldehyde by NCA 18F- obtained from the 18O (p, n) reaction on enriched water [23].
  • The activity of the reductase with p-nitrobenzaldehyde and 3-indolacetaldehyde and the similarity of its physical properties with the 'low Km' aldehyde reductase of porcine brain previously reported indicates that these enzymes may be identical [24].


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