Chemical Compound Review:
AC1L989R (3R)-10,13-dimethyl- 2,3,4,5,6,7,8,9,11,12...
Synonyms:
C03072, 3alpha-Hydroxysteroid
Kedishvili,
Belyaeva,
Gough,
Steckelbroeck,
Watzka,
Reichelt,
Hans,
Stoffel-Wagner,
Heidrich,
Schramm,
Bidlingmaier,
Klingmüller,
Hwang,
Chang,
Hsu,
Hsu,
Li,
Pon,
Stoffel-Wagner,
Centrella,
McCarthy,
Chang,
Labaree,
Hochberg,
Penning,
Burczynski,
Jez,
Hung,
Lin,
Ma,
Moore,
Palackal,
Ratnam,
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- Transient-phase kinetic studies on the nucleotide binding to 3alpha-hydroxysteroid dehydrogenase from Pseudomonas sp. B-0831 using fluorescence stopped-flow procedures. Ueda, S., Oda, M., Imamura, S., Ohnishi, M. Eur. J. Biochem. (2004)
- Mechanistic roles of Ser-114, Tyr-155, and Lys-159 in 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni. Hwang, C.C., Chang, Y.H., Hsu, C.N., Hsu, H.H., Li, C.W., Pon, H.I. J. Biol. Chem. (2005)
- Characterization of a novel type of human microsomal 3alpha -hydroxysteroid dehydrogenase: unique tissue distribution and catalytic properties. Chetyrkin, S.V., Belyaeva, O.V., Gough, W.H., Kedishvili, N.Y. J. Biol. Chem. (2001)
- Characterization of the substrate binding site in rat liver 3alpha-hydroxysteroid/dihydrodiol dehydrogenase. The roles of tryptophans in ligand binding and protein fluorescence. Jez, J.M., Schlegel, B.P., Penning, T.M. J. Biol. Chem. (1996)
- Influence of mirtazapine on plasma concentrations of neuroactive steroids in major depression and on 3alpha-hydroxysteroid dehydrogenase activity. Schüle, C., Romeo, E., Uzunov, D.P., Eser, D., di Michele, F., Baghai, T.C., Pasini, A., Schwarz, M., Kempter, H., Rupprecht, R. Mol. Psychiatry (2006)
- Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alpha-dihydrotestosterone: a potential therapeutic target for androgen-dependent disease. Bauman, D.R., Steckelbroeck, S., Williams, M.V., Peehl, D.M., Penning, T.M. Mol. Endocrinol. (2006)
- Regulation of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase in Comamonas testosteroni: function and relationship of two operators. Xiong, G., Markowetz, S., Maser, E. Chem. Biol. Interact. (2003)
- Role of human type 3 3alpha-hydroxysteroid dehydrogenase (AKR1C2) in androgen metabolism of prostate cancer cells. Rizner, T.L., Lin, H.K., Penning, T.M. Chem. Biol. Interact. (2003)
- Discrete analysis of bile acid in serum and bile with 3alpha-hydroxysteroid dehydrogenase and diaphorase immobilized onto alkylamine glass beads. Rani, K., Garg, P., Pundir, C.S. Indian J. Biochem. Biophys. (2006)
- Members of the nuclear factor 1 transcription factor family regulate rat 3alpha-hydroxysteroid/dihydrodiol dehydrogenase (3alpha-HSD/DD AKR1C9) gene expression: a member of the aldo-keto reductase superfamily. Hung, C.F., Penning, T.M. Mol. Endocrinol. (1999)
- Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate. Jin, Y., Stayrook, S.E., Albert, R.H., Palackal, N.T., Penning, T.M., Lewis, M. Biochemistry (2001)
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- Characterization of the 5alpha-reductase-3alpha-hydroxysteroid dehydrogenase complex in the human brain. Steckelbroeck, S., Watzka, M., Reichelt, R., Hans, V.H., Stoffel-Wagner, B., Heidrich, D.D., Schramm, J., Bidlingmaier, F., Klingmüller, D. J. Clin. Endocrinol. Metab. (2001)
- Local androgen inactivation in abdominal visceral adipose tissue. Blouin, K., Richard, C., Bélanger, C., Dupont, P., Daris, M., Laberge, P., Luu-The, V., Tchernof, A. J. Clin. Endocrinol. Metab. (2003)
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- Sebocytes are the key regulators of androgen homeostasis in human skin. Fritsch, M., Orfanos, C.E., Zouboulis, C.C. J. Invest. Dermatol. (2001)
- Expression of 5alpha-reductase and 3alpha-hydroxisteroid oxidoreductase in the hippocampus of patients with chronic temporal lobe epilepsy. Stoffel-Wagner, B., Beyenburg, S., Watzka, M., Blümcke, I., Bauer, J., Schramm, J., Bidlingmaier, F., Elger, C.E. Epilepsia (2000)
- 5alpha-reduced androgens may have actions in the hippocampus to enhance cognitive performance of male rats. Frye, C.A., Edinger, K.L., Seliga, A.M., Wawrzycki, J.M. Psychoneuroendocrinology (2004)
- Determination of rat muscles androgen-receptor complexes with methyltrienolone. Tremblay, R.R., Dubé, J.Y., Ho-Kim, M.A., Lesage, R. Steroids (1977)
- Characterization of the human aldehyde reductase gene and promoter. Barski, O.A., Gabbay, K.H., Bohren, K.M. Genomics (1999)
- Genomic structure of rat 3alpha-hydroxysteroid/dihydrodiol dehydrogenase (3alpha-HSD/DD, AKR1C9). Lin, H.K., Hung, C.F., Moore, M., Penning, T.M. J. Steroid Biochem. Mol. Biol. (1999)
- Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate. Lin, H.K., Steckelbroeck, S., Fung, K.M., Jones, A.N., Penning, T.M. Steroids (2004)
- Neurosteroid metabolism in the human brain. Stoffel-Wagner, B. Eur. J. Endocrinol. (2001)
- Further characterization of human microsomal 3alpha-hydroxysteroid dehydrogenase. Chetyrkin, S.V., Hu, J., Gough, W.H., Dumaual, N., Kedishvili, N.Y. Arch. Biochem. Biophys. (2001)
- Cloning of the human RoDH-related short chain dehydrogenase gene and analysis of its structure. Kedishvili, N.Y., Belyaeva, O.V., Gough, W.H. Chem. Biol. Interact. (2001)
- Crystallization and preliminary X-ray analysis of the complex of NADH and 3alpha-hydroxysteroid dehydrogenase from Pseudomonas sp. B-0831. Kataoka, S., Nakamura, S., Ohkubo, T., Ueda, S., Uchiyama, S., Kobayashi, Y., Oda, M. Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. (2006)
- Convenient non-chromatographic assays for the microbial deconjugation and 7alpha-OH bioconversion of taurocholate. MacDonald, I.A., Bishop, J.M., Mahony, D.E., Williams, C.N. Applied microbiology. (1975)