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Chemical Compound Review

Methyl yellow     N,N-dimethyl-4- phenyldiazenyl-aniline

Synonyms: Sudan GG, Fat Yellow, Zlut maselna, CCRIS 251, CHEMBL263116, ...
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Disease relevance of Butter Yellow


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Chemical compound and disease context of Butter Yellow


Biological context of Butter Yellow


Anatomical context of Butter Yellow


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Gene context of Butter Yellow


Analytical, diagnostic and therapeutic context of Butter Yellow

  • Structures of antithrombin III Basel and normal antithrombin III isolated from the same patient were compared by peptide mapping using the dimethylaminoazobenzene isothiocyanate precolumn derivatization technique [29].
  • Isolation and HPLC of N-epsilon-lithocholyl lysine as its fluorescamine and dimethylaminoazobenzene isothiocyanate derivatives [30].
  • Different methods of sequence analysis complemented each other, mainly the manual dimethylaminoazobenzene isothiocyanate method and and the use of liquid-phase sequencer degradations [31].
  • The resultant conjugate was used in a sandwich immunoassay for TSH antigen: silver surfaces coated with anti-TSH antibody captured TSH antigen which in turn captured the DAB-anti-TSH antibody conjugate [22].
  • Survival times were decreased by R and chemotherapy due to combined toxicities of DAB and treatments and were partially restored by MTP [32].


  1. Effects of aliphatic aldehyde metabolism on protein synthesis and thiol compounds in rat liver and hepatoma induced by 4-dimethylaminoazobenzene. Sessa, A., Scalabrino, G., Arnaboldi, A., Perin, A. Cancer Res. (1977) [Pubmed]
  2. Diamine oxidase activity in regenerating rat liver and in 4-dimethylaminoazobenzene-induced and Yoshida AH 130 hepatomas. Sessa, A., Desiderio, M.A., Baizini, M., Perin, A. Cancer Res. (1981) [Pubmed]
  3. Modifications of 3'-methyl-4-dimethylaminoazobenzene carcinogenesis of rat liver and carcinogen metabolism by portacaval anastomosis. Ricco, J.B., Franco, D., Morin, J., Decloître, F., Bismuth, H. Cancer Res. (1977) [Pubmed]
  4. Monoclonal antibodies reacting with normal rat liver cells as probes in hepatocarcinogenesis. Holmes, C.H., Austin, E.B., Fisk, A., Gunn, B., Baldwin, R.W. Cancer Res. (1984) [Pubmed]
  5. Comparative mutagenicity of dimethylaminoazobenzene and analogues in Salmonella. Zeiger, E., Pagano, D.A. Carcinogenesis (1982) [Pubmed]
  6. On the promoting action of tamoxifen in a model of hepatocarcinogenesis induced by p-dimethylaminoazobenzene in CF1 mice. Caballero, F., Gerez, E., Oliveri, L., Falcoff, N., Batlle, A., Vazquez, E. Int. J. Biochem. Cell Biol. (2001) [Pubmed]
  7. Detection of carcinogen-induced stimulation of cytochrome P-448-associated enzymes by 14CO2 breath analysis studies using dimethylaminoazobenzene. Hepner, G.W., Piken, E.P. Gastroenterology (1979) [Pubmed]
  8. 4-aminoazobenzene and N,N-dimethyl-4-aminoazobenzene as equipotent hepatic carcinogens in male C57BL/6 X C3H/He F1 mice and characterization of N-(Deoxyguanosin-8-yl)-4-aminoazobenzene as the major persistent hepatic DNA-bound dye in these mice. Delclos, K.B., Tarpley, W.G., Miller, E.C., Miller, J.A. Cancer Res. (1984) [Pubmed]
  9. Adducts from the reaction of N-benzoyloxy-N-methyl-4-aminoazobenzene with deoxyguanosine or DNA in vitro and from hepatic DNA of mice treated with N-methyl- or N,N-dimethyl-4-aminoazobenzene. Tarpley, W.G., Miller, J.A., Miller, E.C. Cancer Res. (1980) [Pubmed]
  10. Changes in polyamine levels and protein synthesis rate during rat liver carcinogenesis induced by 4-dimethylaminoazobenzene. Perin, A., Sessa, A. Cancer Res. (1978) [Pubmed]
  11. Glutathione transferases in primary rat hepatomas: the isolation of a form with GSH peroxidase activity. Meyer, D.J., Beale, D., Tan, K.H., Coles, B., Ketterer, B. FEBS Lett. (1985) [Pubmed]
  12. Antitumour effects of tilorone hydrochloride on the in vivo growth of chemically induced and spontaneously arising rat tumours. Basley, W.A., Rees, R.C., Greager, J.A., Baldwin, R.W. Chemotherapy. (1981) [Pubmed]
  13. Transgenic mice containing hepatitis B virus sequences are more susceptible to carcinogen-induced hepatocarcinogenesis. Dragani, T.A., Manenti, G., Farza, H., Della Porta, G., Tiollais, P., Pourcel, C. Carcinogenesis (1990) [Pubmed]
  14. Primary structure of a Thomsen-Friedenreich-antigen-specific lectin, jacalin [Artocarpus integrifolia (jack fruit) agglutinin]. Evidence for the presence of an internal repeat. Mahanta, S.K., Sanker, S., Rao, N.V., Swamy, M.J., Surolia, A. Biochem. J. (1992) [Pubmed]
  15. Interaction of cimetidine with P450 in a mouse model of hepatocarcinogenesis initiation. Caballero, F., Gerez, E., Batlle, A., Vazquez, E. Br. J. Cancer (2002) [Pubmed]
  16. DNA damage induced by red food dyes orally administered to pregnant and male mice. Tsuda, S., Murakami, M., Matsusaka, N., Kano, K., Taniguchi, K., Sasaki, Y.F. Toxicol. Sci. (2001) [Pubmed]
  17. Regulation of thiol environment of the N-demethylation and ring hydroxylation of N,N-dimethyl-4-aminoazobenzene (DAB) by rat liver microsomes. Levine, W.G. Drug Metab. Dispos. (1986) [Pubmed]
  18. Cytosolic factors that alter the metabolism of N,N-dimethyl-4-aminoazobenzene by rat liver microsomes. Levine, W.G., Lee, S.B. Biochem. Pharmacol. (1983) [Pubmed]
  19. Role of isozymes of cytochrome P-450 in the metabolism of N,N-dimethyl-4-aminoazobenzene in the rat. Levine, W.G., Lu, A.Y. Drug Metab. Dispos. (1982) [Pubmed]
  20. Azoreduction of dimethylaminoazobenzene (DAB) in primary cultures of rat hepatocytes. Effect of hypolipidemic agents. Stoddart, A.M., Levine, W.G. Drug Metab. Dispos. (1990) [Pubmed]
  21. Endogenous xenobiotic enzyme levels in mammalian cells. McGregor, D.B., Edwards, I., Wolf, C.R., Forrester, L.M., Caspary, W.J. Mutat. Res. (1991) [Pubmed]
  22. Immunoassay employing surface-enhanced Raman spectroscopy. Rohr, T.E., Cotton, T., Fan, N., Tarcha, P.J. Anal. Biochem. (1989) [Pubmed]
  23. N-terminal sequence analysis of polypeptide at the picomole level. Chang, J.Y. Biochem. J. (1981) [Pubmed]
  24. Promoting effect of 4-dimethylaminoazobenzene on enzyme altered foci induced in rat liver by N-nitrosodiethanolamine. Schwarz, M., Pearson, D., Port, R., Kunz, W. Carcinogenesis (1984) [Pubmed]
  25. Cell cycle arrest and modulation of HO-1 expression induced by acetyl salicylic acid in hepatocarcinogenesis. Sacca, P., Caballero, F., Batlle, A., Vazquez, E. Int. J. Biochem. Cell Biol. (2004) [Pubmed]
  26. Heme biosynthesis pathway regulation in a model of hepatocarcinogenesis pre-initiation. Polo, C.F., Vazquez, E.S., Caballero, F., Gerez, E., Battle, A.M. Comp. Biochem. Physiol., B (1992) [Pubmed]
  27. Effect of hepatocarcinogens on epoxide hydrolase and other xenobiotic metabolizing enzymes. Dent, J.G., Graichen, M.E. Carcinogenesis (1982) [Pubmed]
  28. Isolation and partial purification of mitochondrial and cytosolic rhodanese from liver of normal and p-dimethylaminoazobenzene treated mice. Vazquez, E., Polo, C., Stedile, G., Schebor, C., Karahanian, E., Batlle, A. Int. J. Biochem. Cell Biol. (1995) [Pubmed]
  29. Antithrombin III Basel. Identification of a Pro-Leu substitution in a hereditary abnormal antithrombin with impaired heparin cofactor activity. Chang, J.Y., Tran, T.H. J. Biol. Chem. (1986) [Pubmed]
  30. Isolation and HPLC of N-epsilon-lithocholyl lysine as its fluorescamine and dimethylaminoazobenzene isothiocyanate derivatives. Nair, P.P., Kessie, G., Patnaik, R., Guidry, C. Steroids (1994) [Pubmed]
  31. Sorbitol dehydrogenase. The primary structure of the sheep-liver enzyme. Jeffery, J., Cederlund, E., Jörnvall, H. Eur. J. Biochem. (1984) [Pubmed]
  32. Combined radiotherapy, chemotherapy, and maltose tetrapalmitate immunotherapy in the treatment of 4'dimethylaminoazobenzene-induced liver cancer. Nigam, V.N., Brière, N., Bonaventure, J., Pageau, R., Bissonnette, E., Brailovsky, C., Madarnas, P. Anticancer Res. (1986) [Pubmed]
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