Chemical Compound Review:
ENADOLINE 2-benzofuran-4-yl-N-methyl-N- [(5S,7S,8S)-7...
Synonyms:
Enadoline HCl, SureCN122595, CI-977, CHEMBL2106706, CAM 570, ...
This record was replaced with 60768.
- The effect of the kappa-opioid receptor agonist CI-977 in a rat model of focal cerebral ischaemia. Kusumoto, K., Mackay, K.B., McCulloch, J. Brain Res. (1992)
- Focal cerebral ischemia in the cat: pretreatment with a kappa-1 opioid receptor agonist, CI-977. Mackay, K.B., Kusumoto, K., Graham, D.I., McCulloch, J. Brain Res. (1993)
- The anticonvulsant action of CI-977, a selective kappa-opioid receptor agonist: a possible involvement of the glycine/NMDA receptor complex. Singh, L., Vass, C.A., Hunter, J.C., Woodruff, G.N., Hughes, J. Eur. J. Pharmacol. (1990)
- Effect of the kappa-1 opioid agonist CI-977 on ischemic brain damage and cerebral blood flow after middle cerebral artery occlusion in the rat. Mackay, K.B., Kusumoto, K., Graham, D.I., McCulloch, J. Brain Res. (1993)
- Diuretic effects, pharmacokinetics, and safety of a new centrally acting kappa-opioid agonist (CI-977) in humans. Reece, P.A., Sedman, A.J., Rose, S., Wright, D.S., Dawkins, R., Rajagopalan, R. Journal of clinical pharmacology. (1994)
- Functional implications of kappa opioid receptor-mediated modulation of glutamate transmission in the output regions of the basal ganglia in rodent and primate models of Parkinson's disease. Maneuf, Y.P., Mitchell, I.J., Crossman, A.R., Woodruff, G.N., Brotchie, J.M. Brain Res. (1995)
- Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists. Subramanian, G., Paterlini, M.G., Larson, D.L., Portoghese, P.S., Ferguson, D.M. J. Med. Chem. (1998)
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- Electrophysiological and antiarrhythmic actions of the kappa agonist PD 129290, and its R,R (+)-enantiomer, PD 129289. Pugsley, M.K., Saint, D.A., Penz, M.P., Walker, M.J. Br. J. Pharmacol. (1993)
- A highly selective kappa-opioid receptor agonist, CI-977, reduces excitatory synaptic potentials in the rat locus coeruleus in vitro. Pinnock, R.D. Neuroscience (1992)
- The neuroprotective kappa-opioid CI-977 alters glutamate-induced calcium signaling in vitro. DeCoster, M.A., Conover, J.R., Hunter, J.C., Tortella, F.C. Neuroreport (1994)
- CI-977, a novel and selective agonist for the kappa-opioid receptor. Hunter, J.C., Leighton, G.E., Meecham, K.G., Boyle, S.J., Horwell, D.C., Rees, D.C., Hughes, J. Br. J. Pharmacol. (1990)
- Activation of c-fos mRNA in the brain by the kappa-opioid receptor agonist enadoline and the NMDA receptor antagonist dizocilpine. Panegyres, P.K., Hughes, J. Eur. J. Pharmacol. (1997)
- Brain temperature and the neuroprotective action of enadoline and dizocilpine in the gerbil model of global ischaemia. Hayward, N.J., McKnight, A.T., Woodruff, G.N. Eur. J. Pharmacol. (1993)
- Unbound plasma concentrations may predict neuroprotective brain concentrations: a brain microdialysis and pharmacokinetic study of enadoline in rats. Hinton, J.P., Hudson, G. Acta Neurochir. Suppl. (1999)
- Pharmacological properties of R-84760, a novel kappa-opioid receptor agonist. Fujibayashi, K., Sakamoto, K., Watanabe, M., Iizuka, Y. Eur. J. Pharmacol. (1994)
- Effects of highly selective kappa-opioid agonists on EEG power spectra and behavioural correlates in conscious rats. Coltro Campi, C., Clarke, G.D. Pharmacol. Biochem. Behav. (1995)
- Search for the pharmacophore in kappa-agonistic diazabicyclo[3.3.1]nonan-9-one-1,5-diesters and arylacetamides. Brandt, W., Drosihn, S., Haurand, M., Holzgrabe, U., Nachtsheim, C. Arch. Pharm. (Weinheim) (1996)
- Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats. Friese, N., Chevalier, E., Angel, F., Pascaud, X., Junien, J.L., Dahl, S.G., Riviere, P.J. Life Sci. (1997)