Chemical Compound Review:
AIB-OH 2-amino-2-methyl-propanoic acid
Synonyms:
H-Aib-OH, PubChem16474, ACMC-1AYLN, AG-K-62511, H-(ME)ALA-OH, ...
- Increased blood-brain transfer in a rabbit model of acute liver failure. Horowitz, M.E., Schafer, D.F., Molnar, P., Jones, E.A., Blasberg, R.G., Patlak, C.S., Waggoner, J., Fenstermacher, J.D. Gastroenterology (1983)
- Glucocorticoid regulation of amino acid transport in anucleate rat hepatoma (HTC) cells. McDonald, R.A., Gelehrter, T.D. J. Cell Biol. (1981)
- Role of Na+ in alpha-aminoisobutyric acid uptake by membrane vesicles from mouse fibroblasts transformed by simian virus 40. Nishino, H., Schiller, R.M., Parnes, J.R., Isselbacher, K.J. Proc. Natl. Acad. Sci. U.S.A. (1978)
- Greatly decreased susceptibility of nonmetabolizing cells towards detergents. Komor, E., Weber, H., Tanner, W. Proc. Natl. Acad. Sci. U.S.A. (1979)
- Opening the blood-brain and blood-tumor barriers in experimental rat brain tumors: the effect of intracarotid hyperosmolar mannitol on capillary permeability and blood flow. Hiesiger, E.M., Voorhies, R.M., Basler, G.A., Lipschutz, L.E., Posner, J.B., Shapiro, W.R. Ann. Neurol. (1986)
- Mechanisms of hypochlorite injury of target cells. Schraufstätter, I.U., Browne, K., Harris, A., Hyslop, P.A., Jackson, J.H., Quehenberger, O., Cochrane, C.G. J. Clin. Invest. (1990)
- Clearance and early hydrolysis of atrial natriuretic factor in vivo. Structural analysis of cleavage sites and design of an analogue that inhibits hormone cleavage. Condra, C.L., Leidy, E.A., Bunting, P., Colton, C.D., Nutt, R.F., Rosenblatt, M., Jacobs, J.W. J. Clin. Invest. (1988)
- Insulin resistance in uremia. Characterization of insulin action, binding, and processing in isolated hepatocytes from chronic uremic rats. Kauffman, J.M., Caro, J.F. J. Clin. Invest. (1983)
- Effects of cold preservation and rewarming on rat liver cell volume regulation and concentrative amino acid uptake. Serrar, H., Haddad, P. Gastroenterology (1997)
- Amino acid and sugar transport incells permissively infected with simian virus 40. Miller, M.S., Kwock, L., Wallach, D.F. Cancer Res. (1975)
- The effect of hyperosmotic blood-brain barrier disruption on blood-to-tissue transport in ENU-induced gliomas. Warnke, P.C., Blasberg, R.G., Groothuis, D.R. Ann. Neurol. (1987)
- Imaging experimental brain tumors with 1-aminocyclopentane carboxylic acid and alpha-aminoisobutyric acid: comparison to fluorodeoxyglucose and diethylenetriaminepentaacetic acid in morphologically defined tumor regions. Uehara, H., Miyagawa, T., Tjuvajev, J., Joshi, R., Beattie, B., Oku, T., Finn, R., Blasberg, R. J. Cereb. Blood Flow Metab. (1997)
- Effect of steroids on edema and sodium uptake of the brain during focal ischemia in rats. Betz, A.L., Coester, H.C. Stroke (1990)
- Tumor imaging with carbon-11 labeled alpha-aminoisobutyric acid (AIB) in a patient with advanced malignant melanoma. Conti, P.S., Sordillo, P.P., Schmall, B., Benua, R.S., Bading, J.R., Bigler, R.E., Laughlin, J.S. European journal of nuclear medicine. (1986)
- Sodium-stimulated active transport of aminoisobutyric acid by reconstituted vesicles from partially purified plasma membranes of mouse fibroblasts transformed by simian virus 40. Nishino, H., Tillotson, L.G., Schiller, R.M., Inui, K.I., Isselbacher, K.J. Proc. Natl. Acad. Sci. U.S.A. (1978)
- Sodium-stimulated alpha-aminoisobutyric acid transport by membrane vesicles from simian virus-transformed mouse cells. Hamilton, R.T., Nilsen-Hamilton, M. Proc. Natl. Acad. Sci. U.S.A. (1976)
- Induction by lithium ion of multiplication of mouse mammary epithelium in culture. Hori, C., Oka, T. Proc. Natl. Acad. Sci. U.S.A. (1979)
- Dissociation of cell density and cell cycle effects on the rate of transport of alpha-aminoisobutyric acid in 3T3 cells. Moya, F., Glaser, L. J. Biol. Chem. (1980)
- Regulation of active alpha-aminoisobutyric acid transport expressed in membrane vesicles from mouse fibroblasts. Lever, J.E. Proc. Natl. Acad. Sci. U.S.A. (1976)
- Lipoprotein-induced insulin resistance in aortic endothelium. Berliner, J.A., Frank, H.J., Karasic, D., Capdeville, M. Diabetes (1984)
- Expression of the mammalian system A neutral amino acid transporter in Xenopus oocytes. Tarnuzzer, R.W., Campa, M.J., Qian, N.X., Englesberg, E., Kilberg, M.S. J. Biol. Chem. (1990)
- Stimulatory effects of ethanol on amino acid transport by rat fetal hepatocytes. Heitman, D.W., Frosto, T.A., Schenker, S., Henderson, G.I. Hepatology (1987)
- The acute and chronic effects of glucocorticoids on insulin receptor and insulin responsiveness. Transient fluctuations in intracellular receptor level parallel transient fluctuations in responsiveness. Knutson, V.P. J. Biol. Chem. (1986)
- Neutral amino acid transport. Characterization of the A and L systems in isolated rat hepatocytes. Le Cam, A., Freychet, P. J. Biol. Chem. (1977)
- Metabolic effects induced by epidermal growth factor (EGF) in cells expressing EGF receptor mutants. Scimeca, J.C., Ballotti, R., Alengrin, F., Honegger, A.M., Ullrich, A., Schlessinger, J., Obberghen, E.V. J. Biol. Chem. (1989)
- Differential permeability and quantitative MR imaging of a human lung carcinoma brain xenograft in the nude rat. Barnett, P.A., Roman-Goldstein, S., Ramsey, F., McCormick, C.I., Sexton, G., Szumowski, J., Neuwelt, E.A. Am. J. Pathol. (1995)
- Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor. Shimizu, N., Guo, J., Gardella, T.J. J. Biol. Chem. (2001)
- Fibroblasts from a patient with leprechaunism are resistant to insulin, epidermal growth factor, and somatomedin C. Kaplowitz, P.B., D'Ercole, A.J. J. Clin. Endocrinol. Metab. (1982)
- Modifications of position 12 in parathyroid hormone and parathyroid hormone related protein: toward the design of highly potent antagonists. Chorev, M., Goldman, M.E., McKee, R.L., Roubini, E., Levy, J.J., Gay, C.T., Reagan, J.E., Fisher, J.E., Caporale, L.H., Golub, E.E. Biochemistry (1990)
- Role of prolactin versus growth hormone on islet B-cell proliferation in vitro: implications for pregnancy. Brelje, T.C., Sorenson, R.L. Endocrinology (1991)
- Inhibition of pancreatic alpha-aminoisobutyric acid uptake by cholecystokinin and other secretagogues. Iwamoto, Y., Williams, J.A. Am. J. Physiol. (1980)
- Concurrent measurements of blood flow and transcapillary transport in xenotransplanted human gliomas in immunosuppressed rats. Vriesendorp, F.J., Peagram, C., Bigner, D.D., Groothuis, D.R. J. Natl. Cancer Inst. (1987)
- Inhibition by colchicine of changes in amino acid transport and initiation of DNA synthesis in regenerating rat liver. Walker, P.R., Whitfield, J.F. Proc. Natl. Acad. Sci. U.S.A. (1978)
- Peptaibol antibiotics: a study on the helical structure of the 2-9 sequence of emerimicins III and IV. Benedetti, E., Bavoso, A., Di Blasio, B., Pavone, V., Pedone, C., Toniolo, C., Bonora, G.M. Proc. Natl. Acad. Sci. U.S.A. (1982)
- Regional localization of a glioma-associated antigen defined by monoclonal antibody 81C6 in vivo: kinetics and implications for diagnosis and therapy. Blasberg, R.G., Nakagawa, H., Bourdon, M.A., Groothuis, D.R., Patlak, C.S., Bigner, D.D. Cancer Res. (1987)
- Nucleocytoplasmic transport and distribution of an amino acid, in situ. Frank, M., Horowitz, S.B. J. Cell. Sci. (1975)