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Chemical Compound Review

CID6327573     tributyltin hydrate

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Disease relevance of tributyltin


Psychiatry related information on tributyltin


High impact information on tributyltin


Biological context of tributyltin


Anatomical context of tributyltin


Associations of tributyltin with other chemical compounds


Gene context of tributyltin

  • A Lord endoprosthesis was used in nine hips and a Biomet endoprosthesis in six [23].
  • METHODS: Three types of reconstruction nails (the Russell-Taylor Delta [Smith & Nephew, Memphis, TN], the Uniflex [Biomet, Warsaw, IN], Alta CFX [Howmedica-Osteonics, Rutherford, NJ]) and the Long Gamma nail (Howmedica-Osteonics, Rutherford, NJ), each measuring 11 x 380 mm, were inserted in fiberglass composite femurs [24].
  • Fifty-one primary consecutive cementless AGC 2000 (Anatomically Graduated Components, Biomet, Warsaw, IN) total knee arthroplasties were performed during 1985 through 1990 in 40 patients with rheumatoid arthritis [25].
  • We hypothesized that the posterior-to-anterior (PA) calcaneal interlocking screw of the Biomet Ankle Arthrodesis Nail would increase rotational stability secondary to increased bone purchase compared with the standard lateral-to-medial (transverse) screw [26].
  • A 48 year-old right-hand-dominant man presented to our institution with paresthesia and loss of feeling along the median nerve distribution of the right hand 1 week after undergoing minimally open carpal tunnel release with the Biomet Indiana Tome at another hospital [27].

Analytical, diagnostic and therapeutic context of tributyltin

  • This study evaluates anisotropy and oxidative resistance in a novel, radiation crosslinked (50 kGy) UHMWPE material (ArComXL: Biomet, Inc., Warsaw, IN), incorporating solid-state, deformation processing by extrusion below the melt transition for application in total hip arthroplasty [28].
  • The poor survival of Biomet cementless prostheses in our series seems to be related to the poor survival of the cup [29].
  • These findings were confirmed by the results of the biosensor test (Biomet) which indicated that all zinc was indeed bioavailable [30].
  • We reviewed 231 patients who had undergone total knee replacement with an AGC (Biomet) implant over a period of 2.5 years [31].
  • We measured the size and volume of the femoral broaches and stems supplied with three commercial total hip replacement (THR) systems (JRI Furlong, Biomet Stanmore, and Howmedica Exeter) [32].


  1. Bacteriostatic and bactericidal modes of action of bis(tributyltin)oxide on Legionella pneumophila. Soracco, R.J., Pope, D.H. Appl. Environ. Microbiol. (1983) [Pubmed]
  2. Toxicity of bis(tri-n-butyltin)oxide in the rat. I. Short-term effects on general parameters and on the endocrine and lymphoid systems. Krajnc, E.I., Wester, P.W., Loeber, J.G., van Leeuwen, F.X., Vos, J.G., Vaessen, H.A., van der Heijden, C.A. Toxicol. Appl. Pharmacol. (1984) [Pubmed]
  3. Evaluation of the genetic and embryotoxic effects of bis(tri-n-butyltin)oxide (TBTO), a broad-spectrum pesticide, in multiple in vivo and in vitro short-term tests. Davis, A., Barale, R., Brun, G., Forster, R., Günther, T., Hautefeuille, H., van der Heijden, C.A., Knaap, A.G., Krowke, R., Kuroki, T. Mutat. Res. (1987) [Pubmed]
  4. A rat cytomegalovirus infection model as a tool for immunotoxicity testing. Garssen, J., Van der Vliet, H., De Klerk, A., Goettsch, W., Dormans, J.A., Bruggeman, C.A., Osterhaus, A.D., Van Loveren, H. Eur. J. Pharmacol. (1995) [Pubmed]
  5. Toxicity of bis(tri-n-butyltin)oxide in the rat. II. Suppression of thymus-dependent immune responses and of parameters of nonspecific resistance after short-term exposure. Vos, J.G., de Klerk, A., Krajnc, E.I., Kruizinga, W., van Ommen, B., Rozing, J. Toxicol. Appl. Pharmacol. (1984) [Pubmed]
  6. Oral bis(tri-n-butyltin) oxide in pregnant mice. I. Potential influence of maternal behavior on postnatal mortality. Baroncelli, S., Karrer, D., Turillazzi, P.G. Journal of toxicology and environmental health. (1995) [Pubmed]
  7. Differential effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin, bis(tri-n-butyltin) oxide and cyclosporine on thymus histophysiology. De Waal, E.J., Schuurman, H.J., Van Loveren, H., Vos, J.G. Crit. Rev. Toxicol. (1997) [Pubmed]
  8. Bias and error in estimates of mean shape in geometric morphometrics. Rohlf, F.J. J. Hum. Evol. (2003) [Pubmed]
  9. Actions of orally administered organotin compounds on heme metabolism and cytochrome P-450 content and function in intestinal epithelium. Rosenberg, D.W., Kappas, A. Biochem. Pharmacol. (1989) [Pubmed]
  10. Effects of in vivo exposure to bis(tri-n-butyltin)oxide, hexachlorobenzene, and benzo(a)pyrene on cytokine (receptor) mRNA levels in cultured rat splenocytes and on IL-2 receptor protein levels. Vandebriel, R.J., Meredith, C., Scott, M.P., Roholl, P.J., Van Loveren, H. Toxicol. Appl. Pharmacol. (1998) [Pubmed]
  11. Prenatal or postnatal exposure to bis(tri-n-butyltin)oxide in the rat: postnatal evaluation of teratology and behavior. Crofton, K.M., Dean, K.F., Boncek, V.M., Rosen, M.B., Sheets, L.P., Chernoff, N., Reiter, L.W. Toxicol. Appl. Pharmacol. (1989) [Pubmed]
  12. Bis(tri-n-butyltin)oxide induces programmed cell death (apoptosis) in immature rat thymocytes. Raffray, M., Cohen, G.M. Arch. Toxicol. (1991) [Pubmed]
  13. Butyltins in shellfish, finfish, water and sediment from the Coos Bay estuary (Oregon, USA). Elgethun, K., Neumann, C., Blake, P. Chemosphere (2000) [Pubmed]
  14. Metal availability and soil toxicity after repeated croppings of Thlaspi caerulescens in metal contaminated soils. Keller, C., Hammer, D. Environ. Pollut. (2004) [Pubmed]
  15. The potent induction of intestinal heme oxygenase by the organotin compound, bis(tri-n-butyltin)oxide. Rosenberg, D.W., Anderson, K.E., Kappas, A. Biochem. Biophys. Res. Commun. (1984) [Pubmed]
  16. The cortical epithelium of the rat thymus after in vivo exposure to bis(tri-n-butyltin)oxide (TBTO). An (immuno)histological and ultrastructural study. De Waal, E.J., Schuurman, H.J., Rademakers, L.H., Van Loveren, H., Vos, J.G. Arch. Toxicol. (1993) [Pubmed]
  17. Rapid recovery after oxford unicompartmental arthroplasty through a short incision. Price, A.J., Webb, J., Topf, H., Dodd, C.A., Goodfellow, J.W., Murray, D.W. The Journal of arthroplasty. (2001) [Pubmed]
  18. A study of steady state and kinetic regulation of chloride ion and osmotic pressure in hemolymph of oysters, Crassostrea virginica, exposed to tri-n-butyltin. Bokman, E., Laughlin, R.B. Arch. Environ. Contam. Toxicol. (1989) [Pubmed]
  19. Ten-Year Results of ALIZE Acetabular Cup with Hydroxyapatite Coating and AURA Hydroxyapatite-Coated Stem in Total Hip Arthroplasty. Fayard, J.P., Chalencon, F., Passot, J.P., Dupre Latour, L., Edorh, G. The Journal of arthroplasty. (2006) [Pubmed]
  20. Influence of orthopaedic metal and high-density detection on body composition as assessed by dual-energy X-ray absorptiometry. Madsen, O.R., Egsmose, C., Lorentzen, J.S., Lauridsen, U.B., Sørensen, O.H. Clinical physiology (Oxford, England) (1999) [Pubmed]
  21. In vitro exposure effects of cyclosporin A and bis(tri-n-butyltin)oxide on lymphocyte proliferation, cytokine (receptor) mRNA expression, and cell surface marker expression in rat thymocytes and splenocytes. Vandebriel, R.J., Spiekstra, S.W., Hudspith, B.N., Meredith, C., Van Loveren, H. Toxicology (1999) [Pubmed]
  22. In vitro analysis of the elution of tobramycin from a calcium sulfate bone void filler. Pietrzak, W.S., Eppley, B.L. The Journal of craniofacial surgery. (2004) [Pubmed]
  23. Cementless hip arthroplasty in diastrophic dysplasia. Peltonen, J.I., Hoikka, V., Poussa, M., Paavilainen, T., Kaitila, I. The Journal of arthroplasty. (1992) [Pubmed]
  24. Second generation intramedullary nailing of subtrochanteric femur fractures: a biomechanical study of fracture site motion. Roberts, C.S., Nawab, A., Wang, M., Voor, M.J., Seligson, D. Journal of orthopaedic trauma. (2002) [Pubmed]
  25. Cementless total knee arthroplasty in rheumatoid arthritis. A report on 51 AGC knees followed for 54 months. Schrøder, H.M., Aaen, K., Hansen, E.B., Nielsen, P.T., Rechnagel, K. The Journal of arthroplasty. (1996) [Pubmed]
  26. Tibiotalocalcaneal arthrodesis: a biomechanical analysis of the rotational stability of the Biomet Ankle Arthrodesis Nail. Mann, M.R., Parks, B.G., Pak, S.S., Miller, S.D. Foot & ankle international / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society. (2001) [Pubmed]
  27. Complete median nerve transection as a complication of carpal tunnel release with a carpal tunnel tome. Chapman, C.B., Ristic, S., Rosenwasser, M.P. Am J. Orthop. (2001) [Pubmed]
  28. Anisotropy and oxidative resistance of highly crosslinked UHMWPE after deformation processing by solid-state ram extrusion. Kurtz, S.M., Mazzucco, D., Rimnac, C.M., Schroeder, D. Biomaterials (2006) [Pubmed]
  29. Poor survival of cementless Biomet total hip: a report on 1,047 hips from the Finnish Arthroplasty Register. Puolakka, T.J., Pajamäki, K.J., Pulkkinen, P.O., Nevalainen, J.K. Acta orthopaedica Scandinavica. (1999) [Pubmed]
  30. Bioavailability of zinc in runoff water from roofing materials. Heijerick, D.G., Janssen, C.R., Karlèn, C., Wallinder, I.O., Leygraf, C. Chemosphere (2002) [Pubmed]
  31. Infection in knee replacements after previous injection of intra-articular steroid. Papavasiliou, A.V., Isaac, D.L., Marimuthu, R., Skyrme, A., Armitage, A. The Journal of bone and joint surgery. British volume. (2006) [Pubmed]
  32. The femoral cement mantle in three total hip replacements. Mellor, S.J., Ripley, L.G., Ricketts, D.M. International orthopaedics. (2004) [Pubmed]
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