Gene Review:
Cxcl13 - chemokine (C-X-C motif) ligand 13
Mus musculus
Synonyms:
4631412M08Rik, ANGIE2, Angie, B lymphocyte chemoattractant, BCA-1, ...
- Aberrant B1 cell migration into the thymus results in activation of CD4 T cells through its potent antigen-presenting activity in the development of murine lupus. Sato, T., Ishikawa, S., Akadegawa, K., Ito, T., Yurino, H., Kitabatake, M., Yoneyama, H., Matsushima, K. Eur. J. Immunol. (2004)
- Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis. Magliozzi, R., Columba-Cabezas, S., Serafini, B., Aloisi, F. J. Neuroimmunol. (2004)
- CXC chemokine ligand 13 plays a role in experimental autoimmune encephalomyelitis. Bagaeva, L.V., Rao, P., Powers, J.M., Segal, B.M. J. Immunol. (2006)
- A chemokine-driven positive feedback loop organizes lymphoid follicles. Ansel, K.M., Ngo, V.N., Hyman, P.L., Luther, S.A., Förster, R., Sedgwick, J.D., Browning, J.L., Lipp, M., Cyster, J.G. Nature (2000)
- A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Gunn, M.D., Ngo, V.N., Ansel, K.M., Ekland, E.H., Cyster, J.G., Williams, L.T. Nature (1998)
- FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses. Victoratos, P., Lagnel, J., Tzima, S., Alimzhanov, M.B., Rajewsky, K., Pasparakis, M., Kollias, G. Immunity (2006)
- CD4+CD3- cells induce Peyer's patch development: role of alpha4beta1 integrin activation by CXCR5. Finke, D., Acha-Orbea, H., Mattis, A., Lipp, M., Kraehenbuhl, J. Immunity (2002)
- TNF Receptor-Associated Factor 2-Dependent Canonical Pathway Is Crucial for the Development of Peyer's Patches. Piao, J.H., Yoshida, H., Yeh, W.C., Doi, T., Xue, X., Yagita, H., Okumura, K., Nakano, H. J. Immunol. (2007)
- Aberrant high expression of B lymphocyte chemokine (BLC/CXCL13) by C11b+CD11c+ dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLC. Ishikawa, S., Sato, T., Abe, M., Nagai, S., Onai, N., Yoneyama, H., Zhang , Y., Suzuki, T., Hashimoto , S., Shirai, T., Lipp, M., Matsushima, K. J. Exp. Med. (2001)
- CXCL13 is an arrest chemokine for B cells in high endothelial venules. Kanemitsu, N., Ebisuno, Y., Tanaka, T., Otani, K., Hayasaka, H., Kaisho, T., Akira, S., Katagiri, K., Kinashi, T., Fujita, N., Tsuruo, T., Miyasaka, M. Blood (2005)
- The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes. Durand, C.A., Westendorf, J., Tse, K.W., Gold, M.R. Eur. J. Immunol. (2006)
- Role of CXC chemokine ligand 13, CC chemokine ligand (CCL) 19, and CCL21 in the organization and function of nasal-associated lymphoid tissue. Rangel-Moreno, J., Moyron-Quiroz, J., Kusser, K., Hartson, L., Nakano, H., Randall, T.D. J. Immunol. (2005)
- Selectin ligand-independent priming and maintenance of T cell immunity during airborne tuberculosis. Schreiber, T., Ehlers, S., Aly, S., Hölscher, A., Hartmann, S., Lipp, M., Lowe, J.B., Hölscher, C. J. Immunol. (2006)
- Cutting edge: the B cell chemokine CXC chemokine ligand 13/B lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and Peyer's patches and affects B cell trafficking across high endothelial venules. Ebisuno, Y., Tanaka, T., Kanemitsu, N., Kanda, H., Yamaguchi, K., Kaisho, T., Akira, S., Miyasaka, M. J. Immunol. (2003)
- CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity. Ansel, K.M., Harris, R.B., Cyster, J.G. Immunity (2002)
- Design, synthesis, and initial evaluation of high-affinity technetium bombesin analogues. Baidoo, K.E., Lin, K.S., Zhan, Y., Finley, P., Scheffel, U., Wagner, H.N. Bioconjug. Chem. (1998)
- Specific antibody-forming B-lymphocyte colonies. I. Distribution and nature of SRBC antibody-forming B-lymphocyte colonies in mouse lyphomyeloid organs. Claësson, M.H., Layton, J.E., Luckenbach, G.A. Immunology (1978)
- Increased circulating CD11b+CD11c+ dendritic cells (DC) in aged BWF1 mice which can be matured by TNF-alpha into BLC/CXCL13-producing DC. Ishikawa, S., Nagai, S., Sato, T., Akadegawa, K., Yoneyama, H., Zhang, Y.Y., Onai, N., Matsushima, K. Eur. J. Immunol. (2002)
- Altered localization of CXCL13 expressing cells in mice deficient in Pactolus following an inflammatory stimulus. Hojgaard, A., Close, R., Dunn, D.M., Weiss, R.B., Weis, J.J., Weis, J.H. Immunology (2006)
- BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis. Luther, S.A., Lopez, T., Bai, W., Hanahan, D., Cyster, J.G. Immunity (2000)
- Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing. Reif, K., Okkenhaug, K., Sasaki, T., Penninger, J.M., Vanhaesebroeck, B., Cyster, J.G. J. Immunol. (2004)
- Abnormal organogenesis of Peyer's patches in mice deficient for NF-kappaB1, NF-kappaB2, and Bcl-3. Paxian, S., Merkle, H., Riemann, M., Wilda, M., Adler, G., Hameister, H., Liptay, S., Pfeffer, K., Schmid, R.M. Gastroenterology (2002)
- In vivo-activated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokines. Ansel, K.M., McHeyzer-Williams, L.J., Ngo, V.N., McHeyzer-Williams, M.G., Cyster, J.G. J. Exp. Med. (1999)
- CXCR5-transduced bone marrow-derived dendritic cells traffic to B cell zones of lymph nodes and modify antigen-specific immune responses. Wu, M.T., Hwang, S.T. J. Immunol. (2002)
- CXCL13 neutralization reduces the severity of collagen-induced arthritis. Zheng, B., Ozen, Z., Zhang, X., De Silva, S., Marinova, E., Guo, L., Wansley, D., Huston, D.P., West, M.R., Han, S. Arthritis Rheum. (2005)