Gene Review:
Foxa1 - forkhead box A1
Mus musculus
Synonyms:
Forkhead box protein A1, HNF-3-alpha, HNF-3A, Hepatocyte nuclear factor 3-alpha, Hnf-3a, ...
- Expression and role of Foxa proteins in prostate cancer. Mirosevich, J., Gao, N., Gupta, A., Shappell, S.B., Jove, R., Matusik, R.J. Prostate (2006)
- Mild nephrogenic diabetes insipidus caused by Foxa1 deficiency. Behr, R., Brestelli, J., Fulmer, J.T., Miyawaki, N., Kleyman, T.R., Kaestner, K.H. J. Biol. Chem. (2004)
- Decreased expression of hepatocyte nuclear factor 3 alpha during the acute-phase response influences transthyretin gene transcription. Qian, X., Samadani, U., Porcella, A., Costa, R.H. Mol. Cell. Biol. (1995)
- Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head. Lai, E., Prezioso, V.R., Tao, W.F., Chen, W.S., Darnell, J.E. Genes Dev. (1991)
- Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation. Gao, N., Ishii, K., Mirosevich, J., Kuwajima, S., Oppenheimer, S.R., Roberts, R.L., Jiang, M., Yu, X., Shappell, S.B., Caprioli, R.M., Stoffel, M., Hayward, S.W., Matusik, R.J. Development (2005)
- Elevated hepatocyte levels of the Forkhead box A2 (HNF-3beta) transcription factor cause postnatal steatosis and mitochondrial damage. Hughes, D.E., Stolz, D.B., Yu, S., Tan, Y., Reddy, J.K., Watkins, S.C., Diehl, A.M., Costa, R.H. Hepatology (2003)
- Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis. Wan, H., Dingle, S., Xu, Y., Besnard, V., Kaestner, K.H., Ang, S.L., Wert, S., Stahlman, M.T., Whitsett, J.A. J. Biol. Chem. (2005)
- Foxa3 (HNF-3gamma) binds to and activates the rat proglucagon gene promoter but is not essential for proglucagon gene expression. Liu, Y., Shen, W., Brubaker, P.L., Kaestner, K.H., Drucker, D.J. Biochem. J. (2002)
- The role of forkhead box A2 to restrict androgen-regulated gene expression of lipocalin 5 in the mouse epididymis. Yu, X., Suzuki, K., Wang, Y., Gupta, A., Jin, R., Orgebin-Crist, M.C., Matusik, R. Mol. Endocrinol. (2006)
- Foxa3 (hepatocyte nuclear factor 3gamma ) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast. Shen, W., Scearce, L.M., Brestelli, J.E., Sund, N.J., Kaestner, K.H. J. Biol. Chem. (2001)
- The initiation of liver development is dependent on Foxa transcription factors. Lee, C.S., Friedman, J.R., Fulmer, J.T., Kaestner, K.H. Nature (2005)
- Foxa1 and foxa2 interact with the androgen receptor to regulate prostate and epididymal genes differentially. Yu, X., Gupta, A., Wang, Y., Suzuki, K., Mirosevich, J., Orgebin-Crist, M.C., Matusik, R.J. Ann. N. Y. Acad. Sci. (2005)
- Foxa1-Deficient Mice Exhibit Impaired Insulin Secretion due to Uncoupled Oxidative Phosphorylation. Vatamaniuk, M.Z., Gupta, R.K., Lantz, K.A., Doliba, N.M., Matschinsky, F.M., Kaestner, K.H. Diabetes (2006)
- Distinct regulators of Shh transcription in the floor plate and notochord indicate separate origins for these tissues in the mouse node. Jeong, Y., Epstein, D.J. Development (2003)
- Transcription factor HNF-6/OC-1 inhibits the stimulation of the HNF-3alpha/Foxa1 gene by TGF-beta in mouse liver. Plumb-Rudewiez, N., Clotman, F., Strick-Marchand, H., Pierreux, C.E., Weiss, M.C., Rousseau, G.G., Lemaigre, F.P. Hepatology (2004)
- Fine genetic mapping defines the genetic order of Pax9, Tcf3a, and Acrodysplasia (Adp). Watanabe, T., Tarttelin, E., Neubüser, A., Kimura, M., Solter, D. Mamm. Genome (1994)
- Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. Besnard, V., Wert, S.E., Kaestner, K.H., Whitsett, J.A. Am. J. Physiol. Lung Cell Mol. Physiol. (2005)
- The role of hepatocyte nuclear factor-3 alpha (Forkhead Box A1) and androgen receptor in transcriptional regulation of prostatic genes. Gao, N., Zhang, J., Rao, M.A., Case, T.C., Mirosevich, J., Wang, Y., Jin, R., Gupta, A., Rennie, P.S., Matusik, R.J. Mol. Endocrinol. (2003)
- Characterization of a novel Foxa (hepatocyte nuclear factor-3) site in the glucagon promoter that is conserved between rodents and humans. Sharma, S.K., Leinemann, U., Ratke, R., Oetjen, E., Blume, R., Dickel, C., Knepel, W. Biochem. J. (2005)