Gene Review:
GJA4 - gap junction protein, alpha 4, 37kDa
Homo sapiens
Synonyms:
CX37, Connexin-37, Cx37, Gap junction alpha-4 protein
Richard,
Smith,
Bailey,
Itin,
Hohl,
Epstein,
DiGiovanna,
Compton,
Bale,
Kameritsch,
Hoffmann,
Pohl,
Yamada,
Ando,
Shimokata,
Ryan,
Liu,
Herbowy,
Gross,
Hajduczok,
Beyer,
Gemel,
Martínez,
Berthoud,
Valiunas,
Moreno,
Brink,
Kameritsch,
Khandoga,
Nagel,
Hundhausen,
Lidington,
Pohl,
Van Camp,
Coucke,
Speleman,
Van Roy,
Beyer,
Oostra,
Willems,
- Adenoviral delivery of human connexin37 induces endothelial cell death through apoptosis. Seul, K.H., Kang, K.Y., Lee, K.S., Kim, S.H., Beyer, E.C. Biochem. Biophys. Res. Commun. (2004)
- Human hemangiosarcomas have a common polymorphism but no mutations in the connexin37 gene. Saito, T., Krutovskikh, V., Marion, M.J., Ishak, K.G., Bennett, W.P., Yamasaki, H. Int. J. Cancer (2000)
- A genetic polymorphism in connexin 37 as a prognostic marker for atherosclerotic plaque development. Boerma, M., Forsberg, L., Van Zeijl, L., Morgenstern, R., De Faire, U., Lemne, C., Erlinge, D., Thulin, T., Hong, Y., Cotgreave, I.A. J. Intern. Med. (1999)
- Association between C1019T polymorphism of connexin37 and acute myocardial infarction: a study in patients from Sicily. Listì, F., Candore, G., Lio, D., Russo, M., Colonna-Romano, G., Caruso, M., Hoffmann, E., Caruso, C. International journal of cardiology. (2005)
- Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men. Yamada, Y., Ando, F., Shimokata, H. Int. J. Mol. Med. (2007)
- Mutations in the human connexin gene GJB3 cause erythrokeratodermia variabilis. Richard, G., Smith, L.E., Bailey, R.A., Itin, P., Hohl, D., Epstein, E.H., DiGiovanna, J.J., Compton, J.G., Bale, S.J. Nat. Genet. (1998)
- Connexin37 protects against atherosclerosis by regulating monocyte adhesion. Wong, C.W., Christen, T., Roth, I., Chadjichristos, C.E., Derouette, J.P., Foglia, B.F., Chanson, M., Goodenough, D.A., Kwak, B.R. Nat. Med. (2006)
- Genotypes associated with myocardial infarction risk are more common in African Americans than in European Americans. Lanfear, D.E., Marsh, S., Cresci, S., Shannon, W.D., Spertus, J.A., McLeod, H.L. J. Am. Coll. Cardiol. (2004)
- The gene for human gap junction protein connexin37 (GJA4) maps to chromosome 1p35.1, in the vicinity of D1S195. Van Camp, G., Coucke, P., Speleman, F., Van Roy, N., Beyer, E.C., Oostra, B.A., Willems, P.J. Genomics (1995)
- Nitric oxide specifically reduces the permeability of Cx37-containing gap junctions to small molecules. Kameritsch, P., Khandoga, N., Nagel, W., Hundhausen, C., Lidington, D., Pohl, U. J. Cell. Physiol. (2005)
- Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein. Reed, K.E., Westphale, E.M., Larson, D.M., Wang, H.Z., Veenstra, R.D., Beyer, E.C. J. Clin. Invest. (1993)
- Chamber-related differences in connexin expression in the human heart. Vozzi, C., Dupont, E., Coppen, S.R., Yeh, H.I., Severs, N.J. J. Mol. Cell. Cardiol. (1999)
- Gap junction protein phenotypes of the human heart and conduction system. Davis, L.M., Rodefeld, M.E., Green, K., Beyer, E.C., Saffitz, J.E. J. Cardiovasc. Electrophysiol. (1995)
- Descending vasa recta endothelium is an electrical syncytium. Zhang, Q., Cao, C., Mangano, M., Zhang, Z., Silldorff, E.P., Lee-Kwon, W., Payne, K., Pallone, T.L. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2006)
- In vivo modulation of connexins 43 and 26 of human epidermis by topical retinoic acid treatment. Masgrau-Peya, E., Salomon, D., Saurat, J.H., Meda, P. J. Histochem. Cytochem. (1997)
- The influence of surface charges on the conductance of the human connexin37 gap junction channel. Banach, K., Ramanan, S.V., Brink, P.R. Biophys. J. (2000)
- Mutation in the gene for connexin 30.3 in a family with erythrokeratodermia variabilis. Macari, F., Landau, M., Cousin, P., Mevorah, B., Brenner, S., Panizzon, R., Schorderet, D.F., Hohl, D., Huber, M. Am. J. Hum. Genet. (2000)
- Upregulation of connexin 26 between keratinocytes of psoriatic lesions. Labarthe, M.P., Bosco, D., Saurat, J.H., Meda, P., Salomon, D. J. Invest. Dermatol. (1998)
- Heteromeric mixing of connexins: compatibility of partners and functional consequences. Beyer, E.C., Gemel, J., Martínez, A., Berthoud, V.M., Valiunas, V., Moreno, A.P., Brink, P.R. Cell Commun. Adhes. (2001)
- Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. Yamada, Y., Izawa, H., Ichihara, S., Takatsu, F., Ishihara, H., Hirayama, H., Sone, T., Tanaka, M., Yokota, M. N. Engl. J. Med. (2002)
- Opposing effects of nitric oxide on different connexins expressed in the vascular system. Kameritsch, P., Hoffmann, A., Pohl, U. Cell Commun. Adhes. (2003)
- The oestrogen receptor {beta} contributes to sex related differences in endothelial function of murine small arteries via EDHF. Luksha, L., Poston, L., Gustafsson, J.A., Hultenby, K., Kublickiene, K. J. Physiol. (Lond.) (2006)
- Functional expression and biophysical properties of polymorphic variants of the human gap junction protein connexin37. Kumari, S.S., Varadaraj, K., Valiunas, V., Ramanan, S.V., Christensen, E.A., Beyer, E.C., Brink, P.R. Biochem. Biophys. Res. Commun. (2000)
- Intercellular communication between renin expressing As4.1 cells, endothelial cells and smooth muscle cells. Ryan, M.J., Liu, B., Herbowy, M.T., Gross, K.W., Hajduczok, G. Life Sci. (2003)