Gene Review:
Nrgn - neurogranin
Rattus norvegicus
Synonyms:
Neurogranin, Ng, Protein kinase C substrate 7.5 kDa protein, RC3
- Thyroid hormone regulation of RC3, a brain-specific gene encoding a protein kinase-C substrate. Iñiguez, M.A., Rodriguez-Peña, A., Ibarrola, N., Aguilera, M., Muñoz, A., Bernal, J. Endocrinology (1993)
- Characterization of the promoter region and flanking sequences of the neuron-specific gene RC3 (neurogranin). Iñiguez, M.A., Morte, B., Rodriguez-Peña, A., Muñoz, A., Gerendasy, D., Sutcliffe, J.G., Bernal, J. Brain Res. Mol. Brain Res. (1994)
- RC3/neurogranin structure and expression in the caprine brain in relation to congenital hypothyroidism. Piosik, P.A., van Groenigen, M., Ponne, N.J., Bolhuis, P.A., Baas, F. Brain Res. Mol. Brain Res. (1995)
- MAP2 and neurogranin as markers for dendritic lesions in CNS injury. An immunohistochemical study in the rat. Li, G.L., Farooque, M., Lewen, A., Lennmyr, F., Holtz, A., Olsson, Y. APMIS (2000)
- Triiodothyronine administration reverses vitamin A deficiency-related hypo-expression of retinoic acid and triiodothyronine nuclear receptors and of neurogranin in rat brain. Husson, M., Enderlin, V., Alfos, S., Féart, C., Higueret, P., Pallet, V. Br. J. Nutr. (2003)
- Adult rat brain is sensitive to thyroid hormone. Regulation of RC3/neurogranin mRNA. Iñiguez, M.A., Rodriguez-Peña, A., Ibarrola, N., Morreale de Escobar, G., Bernal, J. J. Clin. Invest. (1992)
- Sleep deprivation differentially alters the mRNA and protein levels of neurogranin in rat brain. Neuner-Jehle, M., Rhyner, T.A., Borbély, A.A. Brain Res. (1995)
- Two cis-acting elements in the 3' untranslated region of alpha-CaMKII regulate its dendritic targeting. Mori, Y., Imaizumi, K., Katayama, T., Yoneda, T., Tohyama, M. Nat. Neurosci. (2000)
- Internal initiation of translation of five dendritically localized neuronal mRNAs. Pinkstaff, J.K., Chappell, S.A., Mauro, V.P., Edelman, G.M., Krushel, L.A. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Cell-specific effects of thyroid hormone on RC3/neurogranin expression in rat brain. Iniguez, M.A., De Lecea, L., Guadano-Ferraz, A., Morte, B., Gerendasy, D., Sutcliffe, J.G., Bernal, J. Endocrinology (1996)
- N-methyl-D-aspartate induces neurogranin/RC3 oxidation in rat brain slices. Li, J., Pak, J.H., Huang, F.L., Huang, K.P. J. Biol. Chem. (1999)
- Structural and dynamic characterization of a neuron-specific protein kinase C substrate, neurogranin. Ran, X., Miao, H.H., Sheu, F.S., Yang, D. Biochemistry (2003)
- Localization of the protein kinase C phosphorylation/calmodulin-binding substrate RC3 in dendritic spines of neostriatal neurons. Watson, J.B., Sutcliffe, J.G., Fisher, R.S. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Interactions between neurogranin and calmodulin in vivo. Prichard, L., Deloulme, J.C., Storm, D.R. J. Biol. Chem. (1999)
- Nitric oxide modification of rat brain neurogranin affects its phosphorylation by protein kinase C and affinity for calmodulin. Sheu, F.S., Mahoney, C.W., Seki, K., Huang, K.P. J. Biol. Chem. (1996)
- Calcium-sensitive interaction between calmodulin and modified forms of rat brain neurogranin/RC3. Huang, K.P., Huang, F.L., Li, J., Schuck, P., McPhie, P. Biochemistry (2000)
- RC3/Neurogranin and Ca2+/calmodulin-dependent protein kinase II produce opposing effects on the affinity of calmodulin for calcium. Gaertner, T.R., Putkey, J.A., Waxham, M.N. J. Biol. Chem. (2004)
- Differential responses of protein kinase C substrates (MARCKS, neuromodulin, and neurogranin) phosphorylation to calmodulin and S100. Sheu, F.S., Huang, F.L., Huang, K.P. Arch. Biochem. Biophys. (1995)
- Age-dependent differences in glutamate-induced phosphorylation systems in rat hippocampal slices. Angenstein, F., Buchner, K., Staak, S. Hippocampus. (1999)
- Protein kinase C and F1/GAP-43 gene expression in hippocampus inversely related to synaptic enhancement lasting 3 days. Meberg, P.J., Barnes, C.A., McNaughton, B.L., Routtenberg, A. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Selective recognition of phosphatidylinositol 3,4,5-trisphosphate by a synthetic peptide. Lu, P.J., Chen, C.S. J. Biol. Chem. (1997)
- Characterization of a 7.5-kDa protein kinase C substrate (RC3 protein, neurogranin) from rat brain. Huang, K.P., Huang, F.L., Chen, H.C. Arch. Biochem. Biophys. (1993)
- Nitric oxide modification of rat brain neurogranin. Identification of the cysteine residues involved in intramolecular disulfide bridge formation using site-directed mutagenesis. Mahoney, C.W., Pak, J.H., Huang, K.P. J. Biol. Chem. (1996)
- Glutathiolation of proteins by glutathione disulfide S-oxide derived from S-nitrosoglutathione. Modifications of rat brain neurogranin/RC3 and neuromodulin/GAP-43. Li, J., Huang, F.L., Huang, K.P. J. Biol. Chem. (2001)
- Subtractive cDNA cloning of RC3, a rodent cortex-enriched mRNA encoding a novel 78 residue protein. Watson, J.B., Battenberg, E.F., Wong, K.K., Bloom, F.E., Sutcliffe, J.G. J. Neurosci. Res. (1990)