Gene Review:
Nr3c1 - nuclear receptor subfamily 3, group C,...
Rattus norvegicus
Synonyms:
GR, Gcr, Glucocorticoid receptor, Grl, Nuclear receptor subfamily 3 group C member 1
- Effects of diabetes and recurrent hypoglycemia on the regulation of the sympathoadrenal system and hypothalamo-pituitary-adrenal axis. Inouye, K.E., Chan, O., Yue, J.T., Matthews, S.G., Vranic, M. Am. J. Physiol. Endocrinol. Metab. (2005)
- Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms. Dong, Y., Poellinger, L., Gustafsson, J.A., Okret, S. Mol. Endocrinol. (1988)
- The maternal diet during pregnancy programs altered expression of the glucocorticoid receptor and type 2 11beta-hydroxysteroid dehydrogenase: potential molecular mechanisms underlying the programming of hypertension in utero. Bertram, C., Trowern, A.R., Copin, N., Jackson, A.A., Whorwood, C.B. Endocrinology (2001)
- Hyperthermic stress stimulates the association of both constitutive and inducible isoforms of 70 kDa heat shock protein with rat liver glucocorticoid receptor. Cvoro, A., Matić, G. Int. J. Biochem. Cell Biol. (2002)
- 11-beta Hydroxysteroid dehydrogenase type 2 expression in white adipose tissue is strongly correlated with adiposity. Milagro, F.I., Campión, J., Martínez, J.A. J. Steroid Biochem. Mol. Biol. (2007)
- Neurobiological correlates of individual differences in novelty-seeking behavior in the rat: differential expression of stress-related molecules. Kabbaj, M., Devine, D.P., Savage, V.R., Akil, H. J. Neurosci. (2000)
- Altered control of the hypothalamo-pituitary-adrenal axis in adult male rats exposed perinatally to food deprivation and/or dehydration. Sebaai, N., Lesage, J., Vieau, D., Alaoui, A., Dupouy, J.P., Deloof, S. Neuroendocrinology (2002)
- Dopamine-dependent responses to morphine depend on glucocorticoid receptors. Marinelli, M., Aouizerate, B., Barrot, M., Le Moal, M., Piazza, P.V. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Nicotine withdrawal induces subsensitivity of hypothalamic-pituitary-adrenal axis to stress in rats: implications for precipitation of depression during smoking cessation. Semba, J., Wakuta, M., Maeda, J., Suhara, T. Psychoneuroendocrinology (2004)
- Chronic lithium chloride injection increases glucocorticoid receptor but not mineralocorticoid receptor mRNA expression in rat brain. Semba, J., Watanabe, H., Suhara, T., Akanuma, N. Neurosci. Res. (2000)
- In vivo footprinting of rat TAT gene: dynamic interplay between the glucocorticoid receptor and a liver-specific factor. Rigaud, G., Roux, J., Pictet, R., Grange, T. Cell (1991)
- Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA. Miesfeld, R., Rusconi, S., Godowski, P.J., Maler, B.A., Okret, S., Wikström, A.C., Gustafsson, J.A., Yamamoto, K.R. Cell (1986)
- Sequences in the promoter region of the chicken lysozyme gene required for steroid regulation and receptor binding. Renkawitz, R., Schütz, G., von der Ahe, D., Beato, M. Cell (1984)
- DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo. Chandler, V.L., Maler, B.A., Yamamoto, K.R. Cell (1983)
- Specific binding of the glucocorticoid-receptor complex to the mouse mammary tumor proviral promoter region. Pfahl, M. Cell (1982)
- The resistance of the Wistar/Furth rat strain to steroid hypertension. Kayes, K., Ziegler, L., Yu, C.P., Brownie, A.C., Gallant, S. Endocr. Res. (1996)
- Visceromotor and spinal neuronal responses to colorectal distension in rats with aldosterone onto the amygdala. Qin, C., Greenwood-Van Meerveld, B., Foreman, R.D. J. Neurophysiol. (2003)
- Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats. Aisa, B., Tordera, R., Lasheras, B., Del Río, J., Ramírez, M.J. Psychoneuroendocrinology (2007)
- Glucocorticoid receptor and NGFI-A gene expression are induced in the hippocampus after environmental enrichment in adult rats. Olsson, T., Mohammed, A.H., Donaldson, L.F., Henriksson, B.G., Seckl, J.R. Brain Res. Mol. Brain Res. (1994)
- Localization of a negative glucocorticoid response element of the human corticotropin releasing hormone gene. Malkoski, S.P., Handanos, C.M., Dorin, R.I. Mol. Cell. Endocrinol. (1997)
- Steroid receptor heterodimerization demonstrated in vitro and in vivo. Liu, W., Wang, J., Sauter, N.K., Pearce, D. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Reconstitution of glucocorticoid receptor-dependent transcription in vivo. Trotter, K.W., Archer, T.K. Mol. Cell. Biol. (2004)
- Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-beta1-induced apoptosis in rat hepatocytes. Solá, S., Amaral, J.D., Castro, R.E., Ramalho, R.M., Borralho, P.M., Kren, B.T., Tanaka, H., Steer, C.J., Rodrigues, C.M. Hepatology (2005)
- Dynamic changes in subcellular localization of mineralocorticoid receptor in living cells: in comparison with glucocorticoid receptor using dual-color labeling with green fluorescent protein spectral variants. Nishi, M., Ogawa, H., Ito, T., Matsuda, K.I., Kawata, M. Mol. Endocrinol. (2001)
- Enduring, handling-evoked enhancement of hippocampal memory function and glucocorticoid receptor expression involves activation of the corticotropin-releasing factor type 1 receptor. Fenoglio, K.A., Brunson, K.L., Avishai-Eliner, S., Stone, B.A., Kapadia, B.J., Baram, T.Z. Endocrinology (2005)
- Inhibition of 11beta-hydroxysteroid dehydrogenase, the foeto-placental barrier to maternal glucocorticoids, permanently programs amygdala GR mRNA expression and anxiety-like behaviour in the offspring. Welberg, L.A., Seckl, J.R., Holmes, M.C. Eur. J. Neurosci. (2000)
- Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression. Ki, S.H., Cho, I.J., Choi, D.W., Kim, S.G. Mol. Cell. Biol. (2005)
- Dexamethasone suppression of corticosteroid secretion: evaluation of the site of action by receptor measures and functional studies. Cole, M.A., Kim, P.J., Kalman, B.A., Spencer, R.L. Psychoneuroendocrinology (2000)
- Aldosterone modulates glucocorticoid receptor binding in hippocampal cell cultures via the mineralocorticoid receptor. O'Donnell, D., Meaney, M.J. Brain Res. (1994)
- Comparison of the whey acidic protein genes of the rat and mouse. Campbell, S.M., Rosen, J.M., Hennighausen, L.G., Strech-Jurk, U., Sippel, A.E. Nucleic Acids Res. (1984)
- Yin-yang 1 and glucocorticoid receptor participate in the Stat5-mediated growth hormone response of the serine protease inhibitor 2.1 gene. Bergad, P.L., Towle, H.C., Berry, S.A. J. Biol. Chem. (2000)
- Spaceflight modulates insulin-like growth factor binding proteins and glucocorticoid receptor in osteoblasts. Kumei, Y., Shimokawa, H., Katano, H., Akiyama, H., Hirano, M., Mukai, C., Nagaoka, S., Whitson, P.A., Sams, C.F. J. Appl. Physiol. (1998)
- Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat. Szyf, M., Weaver, I.C., Champagne, F.A., Diorio, J., Meaney, M.J. Frontiers in neuroendocrinology. (2005)
- Demonstration of glucocorticoid receptor-like immunoreactivity in glucocorticoid-sensitive vasopressin and corticotropin-releasing factor neurons in the hypothalamic paraventricular nucleus. Uht, R.M., McKelvy, J.F., Harrison, R.W., Bohn, M.C. J. Neurosci. Res. (1988)
- Coordinative mineralocorticoid and glucocorticoid receptor-mediated control of responses to serotonin in rat hippocampus. Joëls, M., De Kloet, E.R. Neuroendocrinology (1992)
- Low endogenous glucocorticoid allows induction of kidney cortical cyclooxygenase-2 during postnatal rat development. Madsen, K., Stubbe, J., Yang, T., Skøtt, O., Bachmann, S., Jensen, B.L. Am. J. Physiol. Renal Physiol. (2004)
- Stimulation of 11-beta-hydroxysteroid dehydrogenase type 2 in rat colon but not in kidney by low dietary NaCl intake. Nørregaard, R., Uhrenholt, T.R., Bistrup, C., Skøtt, O., Jensen, B.L. Am. J. Physiol. Renal Physiol. (2003)
- Long-term antidepressant administration alters corticotropin-releasing hormone, tyrosine hydroxylase, and mineralocorticoid receptor gene expression in rat brain. Therapeutic implications. Brady, L.S., Whitfield, H.J., Fox, R.J., Gold, P.W., Herkenham, M. J. Clin. Invest. (1991)
- 11 beta-Hydroxysteroid dehydrogenase activity and corticosteroid hormone action. Stewart, P.M., Whorwood, C.B. Steroids (1994)
- The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential. Fuhrmann, U., Krattenmacher, R., Slater, E.P., Fritzemeier, K.H. Contraception. (1996)
- Region-specific onset of handling-induced changes in corticotropin-releasing factor and glucocorticoid receptor expression. Fenoglio, K.A., Brunson, K.L., Avishai-Eliner, S., Chen, Y., Baram, T.Z. Endocrinology (2004)
- Lack of decrease in hypothalamic and hippocampal glucocorticoid receptor mRNA during starvation. Makino, S., Kaneda, T., Nishiyama, M., Asaba, K., Hashimoto, K. Neuroendocrinology (2001)
- Corticotropin-releasing factor and glucocorticoid receptor (GR) gene expression in the paraventricular nucleus of immune-challenged transgenic mice expressing type II GR antisense ribonucleic acid. Laflamme, N., Barden, N., Rivest, S. J. Mol. Neurosci. (1997)
- Regulation of hippocampal glucocorticoid receptor gene transcription and protein expression in vivo. Herman, J.P., Spencer, R. J. Neurosci. (1998)