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MeSH Review


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Disease relevance of Epistaxis


High impact information on Epistaxis

  • Epistaxis in hypertensive patients taking thioridazine [6].
  • The incidence of adverse effects in association with intranasal fluticasone propionate appears to be comparable to that observed with placebo; the most frequently reported effects are nasal dryness/burning, epistaxis and headache [7].
  • We conclude that there is a relationship between MVP and low levels of vWF:Ag which may explain the increased incidence of epistaxis in such patients [8].
  • Ninety-seven percent of the bleeding episodes, such as epistaxis, tongue-biting accidents, and other minor lacerations, were successfully managed with a single 50- to 100-percent replacement dose of FVIII [9].
  • Nevertheless, in all of them bleeding mainly due to epistaxis or persistent gum oozing was stopped by a single infusion of desmopressin [10].

Chemical compound and disease context of Epistaxis


Biological context of Epistaxis


Anatomical context of Epistaxis


Gene context of Epistaxis


Analytical, diagnostic and therapeutic context of Epistaxis


  1. Efficacy of unusually high doses of tranexamic acid for the treatment of epistaxis in hereditary hemorrhagic telangiectasia. Sabbà, C., Gallitelli, M., Palasciano, G. N. Engl. J. Med. (2001) [Pubmed]
  2. Effect of high-dose ibuprofen in patients with cystic fibrosis. Konstan, M.W., Byard, P.J., Hoppel, C.L., Davis, P.B. N. Engl. J. Med. (1995) [Pubmed]
  3. Vascular gene transfer driven by endoglin and ICAM-2 endothelial-specific promoters. Velasco, B., Ramírez, J.R., Relloso, M., Li, C., Kumar, S., Lopez-Bote, J.P., Pérez-Barriocanal, F., López-Novoa, J.M., Cowan, P.J., d'Apice, A.J., Bernabéu, C. Gene Ther. (2001) [Pubmed]
  4. Mometasone furoate. A review of its intranasal use in allergic rhinitis. Onrust, S.V., Lamb, H.M. Drugs (1998) [Pubmed]
  5. HHT: A Rare Disease with A Broad Spectrum of Clinical Aspects. Sabbà, C., Gallitelli, M., Pasculli, G., Suppressa, P., Resta, F., Tafaro, G.E. Curr. Pharm. Des. (2006) [Pubmed]
  6. Epistaxis in hypertensive patients taking thioridazine. Idupuganti, S. The American journal of psychiatry. (1982) [Pubmed]
  7. Intranasal fluticasone propionate. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in allergic rhinitis. Bryson, H.M., Faulds, D. Drugs (1992) [Pubmed]
  8. Von Willebrand factor and mitral valve prolapse. Froom, P., Margulis, T., Grenadier, E., Palant, A., David, M., Aghai, E. Thromb. Haemost. (1988) [Pubmed]
  9. Management of severe VWD with cryoprecipitate collected by repeated apheresis of a single dedicated donor. Pomper, G.J., Rick, M.E., Epstein, J.S., Read, E.J., Leitman, S.F. Transfusion (2003) [Pubmed]
  10. Pilot study on the safety and efficacy of desmopressin for the treatment or prevention of bleeding in patients with hematologic malignancies. Castaman, G., Bona, E.D., Schiavotto, C., Trentin, L., D'Emilio, A., Rodeghiero, F. Haematologica (1997) [Pubmed]
  11. Central retinal and posterior ciliary artery occlusion after particle embolization of the external carotid artery system. Mames, R.N., Snady-McCoy, L., Guy, J. Ophthalmology (1991) [Pubmed]
  12. A "bubble-tip" (Airguide) tracheal tube system: its effects on incidence of epistaxis and ease of tube advancement in the subglottic region during nasotracheal intubation. Watanabe, S., Yaguchi, Y., Suga, A., Asakura, N. Anesth. Analg. (1994) [Pubmed]
  13. Use of ureteroscopy and holmium:YAG laser in patients with bleeding diatheses. Kuo, R.L., Aslan, P., Fitzgerald, K.B., Preminger, G.M. Urology (1998) [Pubmed]
  14. Epistaxis as a side effect of oxybutynin in children: report of two cases. Batista, J.E., Caffaratti, J., Garat, J.M. Neurourology and urodynamics. (1994) [Pubmed]
  15. Sodium chloride eye drops as a cause of epistaxis. Case report. Kushner, F.H. Arch. Ophthalmol. (1987) [Pubmed]
  16. DDAVP therapy controls bleeding in Ehlers-Danlos syndrome. Stine, K.C., Becton, D.L. J. Pediatr. Hematol. Oncol. (1997) [Pubmed]
  17. Dipyridamole-induced epistaxis. Mittelman, M., Ogarten, U., Lewinski, U., Djaldetti, M. The Annals of otology, rhinology, and laryngology. (1986) [Pubmed]
  18. Brodifacoum toxicity and treatment in a white-winged wood duck (Cairina scutulata). James, S.B., Raphael, B.L., Cook, R.A. J. Zoo Wildl. Med. (1998) [Pubmed]
  19. Epistaxis in healthy children requiring hospital admission. Brown, N.J., Berkowitz, R.G. Int. J. Pediatr. Otorhinolaryngol. (2004) [Pubmed]
  20. Parotid swelling as the first manifestation of nasopharyngeal carcinoma: a report of two cases. Saw, D., Ho, J.H., Lau, W.H., Chan, J. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. (1986) [Pubmed]
  21. Type I Glanzmann's thrombasthenia in a Great Pyrenees dog. Boudreaux, M.K., Kvam, K., Dillon, A.R., Bourne, C., Scott, M., Schwartz, K.A., Toivio-Kinnucan, M. Vet. Pathol. (1996) [Pubmed]
  22. Zygomycosis due to Conidiobolus coronatus in west Bengal. Thammayya, A. The Indian journal of chest diseases & allied sciences. (2000) [Pubmed]
  23. Genotype-phenotype correlation in hereditary hemorrhagic telangiectasia: mutations and manifestations. Bayrak-Toydemir, P., McDonald, J., Markewitz, B., Lewin, S., Miller, F., Chou, L.S., Gedge, F., Tang, W., Coon, H., Mao, R. Am. J. Med. Genet. A (2006) [Pubmed]
  24. Hereditary haemorrhagic telangiectasia: a questionnaire based study to delineate the different phenotypes caused by endoglin and ALK1 mutations. Berg, J., Porteous, M., Reinhardt, D., Gallione, C., Holloway, S., Umasunthar, T., Lux, A., McKinnon, W., Marchuk, D., Guttmacher, A. J. Med. Genet. (2003) [Pubmed]
  25. Allergic rhinitis and recurrent epistaxis in children. Murray, A.B., Milner, R.A. Ann. Allergy Asthma Immunol. (1995) [Pubmed]
  26. Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome). Shovlin, C.L., Guttmacher, A.E., Buscarini, E., Faughnan, M.E., Hyland, R.H., Westermann, C.J., Kjeldsen, A.D., Plauchu, H. Am. J. Med. Genet. (2000) [Pubmed]
  27. Massive epistaxis from nasal CPAP therapy. Strumpf, D.A., Harrop, P., Dobbin, J., Millman, R.P. Chest (1989) [Pubmed]
  28. Percutaneous embolization to control intractable epistaxis in nasopharyngeal carcinoma. Mok, J.S., Marshall, J.N., Chan, M., van Hasselt, C.A. Head & neck. (1999) [Pubmed]
  29. Management of anterior and posterior epistaxis. Randall, D.A., Freeman, S.B. American family physician. (1991) [Pubmed]
  30. Clinical significance of atrial natriuretic peptide in different diseases of the nose. Yue, W.L. The Journal of otolaryngology. (1989) [Pubmed]
  31. Oxymetazoline in the treatment of posterior epistaxis. Doo, G., Johnson, D.S. Hawaii medical journal. (1999) [Pubmed]
  32. Long-term results of dermatoplasty in the treatment of hereditary haemorrhagic telangiectasia. Ulsø, C., Vase, P., Stoksted, P. The Journal of laryngology and otology. (1983) [Pubmed]
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