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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Laboratories, Hospital

 
 
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Disease relevance of Laboratories, Hospital

 

High impact information on Laboratories, Hospital

 

Biological context of Laboratories, Hospital

 

Anatomical context of Laboratories, Hospital

 

Associations of Laboratories, Hospital with chemical compounds

 

Gene context of Laboratories, Hospital

  • Protein C and protein S assessment in hospital laboratories: which strategy and what role for DNA sequencing [20]?
  • A series of trials for haemocytometry, abnormal haemoglobins, HbA2, HbF, red cell G6PD and peripheral blood films, were carried out with the participation of 126 hospital laboratories, in different regions [21].
  • During control periods, they had to mail blood samples for CRP measurements to the hospital laboratory and received test results 24-48 h later [22].
  • Application of the method to 51 human sera without rigorous control of either temperature or reagent composition yielded a regression equation of y = 1.01x -0.3 when kinetic results (y) were compared with equilibrium results (x) for the same samples analyzed in a hospital laboratory [23].
  • Values for 23 sera with glucose concentrations ranging from 300 to 4300 mg/liter showed a linear correlation coefficient of 0.996 when compared with values reported by a hospital laboratory using the hexokinase method [24].
 

Analytical, diagnostic and therapeutic context of Laboratories, Hospital

  • Eighty-four patients [53 men, 31 women; median age 59 years (range 26-83)], receiving long-term oral anticoagulation (warfarin), were recruited from our Anticoagulation Clinic. Patients were randomized to weekly self-testing or continuing 4-weekly hospital laboratory monitoring of INR [25].
  • The novel glucose biosensor exhibited good selectivity, sensitivity and stability, which showed no apparent loss of activity after 100 consecutive measurements and intermittent usage for 100 days with storage in a phosphate buffer at 4 degrees C. Blood glucose determinations agreed well with standard hospital laboratory analysis [26].
  • Since there is growing evidence for the importance of therapeutic drug monitoring of itraconazole in the prophylaxis and treatment of invasive fungal infections, the method described here is of interest for a large number of tertiary care hospital laboratories [27].
  • There was good correlation between minimum inhibitory concentrations and the results of disc sensitivity tests in this study, 82% with the 100 microgram carbenicillin disc and 90( with the 75 microgram ticarcillin disc, but results reported in the hospital laboratory tests with the carbenicillin disc were less satisfactory (64% correlation) [28].
  • The introduction of immunoassays for homocysteine determination has made assessment of homocysteine status accessible to most routine hospital laboratories, and this review summarizes the evidence on why and how to assess homocysteine as a risk factor for cardiovascular disease in clinical practice [29].

References

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  3. Methicillin-resistant Staphylococcus aureus producing Panton-Valentine leukocidin in a retrospective case series from 12 French hospital laboratories, 2000-2003. Robert, J., Etienne, J., Bertrand, X. Clin. Microbiol. Infect. (2005) [Pubmed]
  4. Ampicillin-resistant Hemophilus influenzae in Canada: nationwide survey of hospital laboratories. Scheifele, D.W. Canadian Medical Association journal. (1979) [Pubmed]
  5. Formalin asthma in hospital laboratory staff. Sakula, A. Lancet (1975) [Pubmed]
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  17. Use of the manual Polybrene test in the routine hospital laboratory. Fisher, G.A. Transfusion (1983) [Pubmed]
  18. An assessment of the operating characteristics of Coulter Counter Model S-Plus STKR. Salvati, A.M., d'Onofrio, G., Berti, P., Cappabianca, M.P., Marsili, G., De Philippis, C., Cossa, L., Quarantelli, M., Zini, G., Mango, G. Haematologica (1991) [Pubmed]
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  20. Protein C and protein S assessment in hospital laboratories: which strategy and what role for DNA sequencing? Labrouche, S., Reboul, M.P., Guérin, V., Vergnes, C., Freyburger, G. Blood Coagul. Fibrinolysis (2003) [Pubmed]
  21. A pilot programme of external quality assessment for general haematology in Italy. Salvati, A.M., Maffi, D., Caprari, P., Marsili, G. Ann. Ist. Super. Sanita (1995) [Pubmed]
  22. Near-patient test for C-reactive protein in general practice: assessment of clinical, organizational, and economic outcomes. Dahler-Eriksen, B.S., Lauritzen, T., Lassen, J.F., Lund, E.D., Brandslund, I. Clin. Chem. (1999) [Pubmed]
  23. A kinetic method for glucose that is insensitive to variations in temperature and enzyme activity. Mieling, G.E., Pardue, H.L., Thompson, J.E., Smith, R.A. Clin. Chem. (1979) [Pubmed]
  24. Amperometric nonenzymatic determination of serum glucose by means of a nickel-catalyst electrode. Schick, K.G., Magearu, V.G., Huber, C.O. Clin. Chem. (1978) [Pubmed]
  25. Patient self-testing is a reliable and acceptable alternative to laboratory INR monitoring. Gardiner, C., Williams, K., Mackie, I.J., Machin, S.J., Cohen, H. Br. J. Haematol. (2005) [Pubmed]
  26. Improved selectivity and stability of glucose biosensor based on in situ electropolymerized polyaniline-polyacrylonitrile composite film. Xue, H., Shen, Z., Li, C. Biosensors & bioelectronics. (2005) [Pubmed]
  27. Determination of itraconazole and hydroxyitraconazole in plasma by use of liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction. Vogeser, M., Spöhrer, U., Schiel, X. Clin. Chem. Lab. Med. (2003) [Pubmed]
  28. Sensitivity to carbenicillin and ticarcillin, and the beta-lactamases of Pseudomonas aeruginosa in the UK in 1978-79. King, J.D., Farmer, T., Reading, C., Sutherland, R. J. Clin. Pathol. (1980) [Pubmed]
  29. Assessment of homocysteine as a cardiovascular risk factor in clinical practice. Clarke, R., Stansbie, D. Ann. Clin. Biochem. (2001) [Pubmed]
 
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