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MeSH Review

Reed-Sternberg Cells

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Disease relevance of Reed-Sternberg Cells


High impact information on Reed-Sternberg Cells


Chemical compound and disease context of Reed-Sternberg Cells


Biological context of Reed-Sternberg Cells


Anatomical context of Reed-Sternberg Cells


Associations of Reed-Sternberg Cells with chemical compounds


Gene context of Reed-Sternberg Cells


Analytical, diagnostic and therapeutic context of Reed-Sternberg Cells


  1. Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice. Amakawa, R., Hakem, A., Kundig, T.M., Matsuyama, T., Simard, J.J., Timms, E., Wakeham, A., Mittruecker, H.W., Griesser, H., Takimoto, H., Schmits, R., Shahinian, A., Ohashi, P., Penninger, J.M., Mak, T.W. Cell (1996) [Pubmed]
  2. Response of refractory Hodgkin's disease to monoclonal anti-CD30 immunotoxin. Falini, B., Bolognesi, A., Flenghi, L., Tazzari, P.L., Broe, M.K., Stein, H., Dürkop, H., Aversa, F., Corneli, P., Pizzolo, G. Lancet (1992) [Pubmed]
  3. CD30, Th2 cytokines and HIV infection: a complex and fascinating link. Del Prete, G., Maggi, E., Pizzolo, G., Romagnani, S. Immunol. Today (1995) [Pubmed]
  4. High prevalence of Epstein-Barr virus in the Reed-Sternberg cells of Hodgkin's disease occurring in Peru. Chang, K.L., Albújar, P.F., Chen, Y.Y., Johnson, R.M., Weiss, L.M. Blood (1993) [Pubmed]
  5. Autocrine growth regulation of CD30 ligand in CD30-expressing Reed-Sternberg cells: distinction between Hodgkin's disease and anaplastic large cell lymphoma. Hsu, P.L., Hsu, S.M. Lab. Invest. (2000) [Pubmed]
  6. Hodgkin's disease with monoclonal and polyclonal populations of Reed-Sternberg cells. Hummel, M., Ziemann, K., Lammert, H., Pileri, S., Sabattini, E., Stein, H. N. Engl. J. Med. (1995) [Pubmed]
  7. c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis. Mathas, S., Lietz, A., Anagnostopoulos, I., Hummel, F., Wiesner, B., Janz, M., Jundt, F., Hirsch, B., Jöhrens-Leder, K., Vornlocher, H.P., Bommert, K., Stein, H., Dörken, B. J. Exp. Med. (2004) [Pubmed]
  8. XIAP-mediated caspase inhibition in Hodgkin's lymphoma-derived B cells. Kashkar, H., Haefs, C., Shin, H., Hamilton-Dutoit, S.J., Salvesen, G.S., Kronke, M., Jurgensmeier, J.M. J. Exp. Med. (2003) [Pubmed]
  9. Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed-Sternberg cells. Kapp, U., Yeh, W.C., Patterson, B., Elia, A.J., Kägi, D., Ho, A., Hessel, A., Tipsword, M., Williams, A., Mirtsos, C., Itie, A., Moyle, M., Mak, T.W. J. Exp. Med. (1999) [Pubmed]
  10. Restin: a novel intermediate filament-associated protein highly expressed in the Reed-Sternberg cells of Hodgkin's disease. Bilbe, G., Delabie, J., Brüggen, J., Richener, H., Asselbergs, F.A., Cerletti, N., Sorg, C., Odink, K., Tarcsay, L., Wiesendanger, W. EMBO J. (1992) [Pubmed]
  11. Lectin staining of carbohydrates of haemic cells. III. The cells of Hodgkin's disease and other lymphomas. Collins, R.D., Jacobson, W., Stoddart, R.W. Histopathology (1982) [Pubmed]
  12. Hodgkin disease as the terminal malignancy in Richter syndrome. Cosgriff, T.M., McCloskey, D.W. Med. Pediatr. Oncol. (1981) [Pubmed]
  13. Expression of the matrix metalloproteinase 9 in Hodgkin's disease is independent of EBV status. Flavell, J.R., Baumforth, K.R., Williams, D.M., Lukesova, M., Madarova, J., Noskova, V., Prochazkova, J., Lowe, D., Kolar, Z., Murray, P.G., Nelson, P.N. MP, Mol. Pathol. (2000) [Pubmed]
  14. Single-cell analysis of Hodgkin and Reed-Sternberg cells: molecular heterogeneity of gene expression and p53 mutations. Trümper, L.H., Brady, G., Bagg, A., Gray, D., Loke, S.L., Griesser, H., Wagman, R., Braziel, R., Gascoyne, R.D., Vicini, S. Blood (1993) [Pubmed]
  15. Morphologically normal, CD30-negative B-lymphocytes with chromosome aberrations in classical Hodgkin's disease: the progenitor cell of the malignant clone? Jansen, M.P., Hopman, A.H., Bot, F.J., Haesevoets, A., Stevens-Kroef, M.J., Arends, J.W., Jox, A., Wolf, J., Ramaekers, F.C., Schouten, H.C. J. Pathol. (1999) [Pubmed]
  16. Isolation and analysis of two strongly transforming isoforms of the Epstein-Barr-Virus(EBV)-encoded latent membrane protein-1 (LMP1) from a single Hodgkin's lymphoma. Mehl, A.M., Fischer, N., Rowe, M., Hartmann, F., Daus, H., Trümper, L., Pfreundschuh, M., Müller-Lantzsch, N., Grässer, F.A. Int. J. Cancer (1998) [Pubmed]
  17. Anomalous retinoblastoma protein expression in Sternberg-Reed cells in Hodgkin's disease: a comparative study with p53 and Ki67 expression. Sánchez-Beato, M., Martínez-Montero, J.C., Doussis-Anagnostopoulou, T.A., Gatter, K.C., García, J., García, J.F., LLoret, E., Piris, M.A. Br. J. Cancer (1996) [Pubmed]
  18. Expression of c-myc and bcl-2 oncogene products in Reed-Sternberg cells independent of presence of Epstein-Barr virus. Jiwa, N.M., Kanavaros, P., van der Valk, P., Walboomers, J.M., Horstman, A., Vos, W., Mullink, H., Meijer, C.J. J. Clin. Pathol. (1993) [Pubmed]
  19. Expression of functional CD40 antigen on Reed-Sternberg cells and Hodgkin's disease cell lines. Carbone, A., Gloghini, A., Gattei, V., Aldinucci, D., Degan, M., De Paoli, P., Zagonel, V., Pinto, A. Blood (1995) [Pubmed]
  20. Hodgkin/Reed-Sternberg cells induce fibroblasts to secrete eotaxin, a potent chemoattractant for T cells and eosinophils. Jundt, F., Anagnostopoulos, I., Bommert, K., Emmerich, F., Müller, G., Foss, H.D., Royer, H.D., Stein, H., Dörken, B. Blood (1999) [Pubmed]
  21. The anti-CD30 monoclonal antibody SGN-30 promotes growth arrest and DNA fragmentation in vitro and affects antitumor activity in models of Hodgkin's disease. Wahl, A.F., Klussman, K., Thompson, J.D., Chen, J.H., Francisco, L.V., Risdon, G., Chace, D.F., Siegall, C.B., Francisco, J.A. Cancer Res. (2002) [Pubmed]
  22. Coexpression of CD15 and CD20 by Reed-Sternberg cells in Hodgkin's disease. Zukerberg, L.R., Collins, A.B., Ferry, J.A., Harris, N.L. Am. J. Pathol. (1991) [Pubmed]
  23. Lack of effect of colony-stimulating factors, interleukins, interferons, and tumor necrosis factor on the growth and differentiation of cultured Reed-Sternberg cells. Comparison with effects of phorbol ester and retinoic acid. Hsu, S.M., Hsu, P.L. Am. J. Pathol. (1990) [Pubmed]
  24. Expression of prostaglandin H synthase (cyclooxygenase) in Hodgkin's mononuclear and Reed-Sternberg cells. Functional resemblance between H-RS cells and histiocytes or interdigitating reticulum cells. Hsu, S.M., Hsu, P.L., Lo, S.S., Wu, K.K. Am. J. Pathol. (1988) [Pubmed]
  25. Monoclonal antibodies in the diagnosis of Hodgkin's disease. The search for a rational panel. Chittal, S.M., Caverivière, P., Schwarting, R., Gerdes, J., Al Saati, T., Rigal-Huguet, F., Stein, H., Delsol, G. Am. J. Surg. Pathol. (1988) [Pubmed]
  26. CD 15 antigen in Hodgkin's disease. Petrella, T., Michiels, J.F., Michiels, R., Collin, F., Nabholtz, J.M., Friedman, S., Fargeot, P. Pathol. Res. Pract. (1989) [Pubmed]
  27. Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells. Hinz, M., Löser, P., Mathas, S., Krappmann, D., Dörken, B., Scheidereit, C. Blood (2001) [Pubmed]
  28. Expression and function of CD40 on Hodgkin and Reed-Sternberg cells and the possible relevance for Hodgkin's disease. Gruss, H.J., Hirschstein, D., Wright, B., Ulrich, D., Caligiuri, M.A., Barcos, M., Strockbine, L., Armitage, R.J., Dower, S.K. Blood (1994) [Pubmed]
  29. Interleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma. Skinnider, B.F., Elia, A.J., Gascoyne, R.D., Trümper, L.H., von Bonin, F., Kapp, U., Patterson, B., Snow, B.E., Mak, T.W. Blood (2001) [Pubmed]
  30. Coexpression of BMI-1 and EZH2 polycomb group genes in Reed-Sternberg cells of Hodgkin's disease. Raaphorst, F.M., van Kemenade, F.J., Blokzijl, T., Fieret, E., Hamer, K.M., Satijn, D.P., Otte, A.P., Meijer, C.J. Am. J. Pathol. (2000) [Pubmed]
  31. MDM2 and p21WAF1/CIP1, wild-type p53-induced proteins, are regularly expressed by Sternberg-Reed cells in Hodgkin's disease. Sánchez-Beato, M., Piris, M.A., Martínez-Montero, J.C., García, J.F., Villuendas, R., García, F.J., Orradre, J.L., Martínez, P. J. Pathol. (1996) [Pubmed]
  32. Ki-4(scFv)-ETA', a new recombinant anti-CD30 immunotoxin with highly specific cytotoxic activity against disseminated Hodgkin tumors in SCID mice. Barth, S., Huhn, M., Matthey, B., Tawadros, S., Schnell, R., Schinköthe, T., Diehl, V., Engert, A. Blood (2000) [Pubmed]
  33. Reed-Sternberg cells in Hodgkin's disease contain fibronectin. Resnick, G.D., Nachman, R.L. Blood (1981) [Pubmed]
  34. Protease receptors in Hodgkin's disease: expression of the factor Xa receptor, effector cell protease receptor-1, in Reed-Sternberg cells. Adida, C., Ambrosini, G., Plescia, J., Crotty, P.L., Costa, J., Altieri, D.C. Blood (1996) [Pubmed]
  35. Quantitative approach to the immunohistochemical analysis of p53 antioncogene and CD30 antigen in Hodgkin' disease. Chilosi, M., Montagna, L., Lestani, M., Menestrina, F., Mariuzzi, G.M. In Vivo (1993) [Pubmed]
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