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MeSH Review


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Disease relevance of Hemodiafiltration


High impact information on Hemodiafiltration

  • The detoxification capacities of single-pass albumin dialysis (SPAD), the molecular adsorbents recirculation system, (MARS) and continuous veno-venous hemodiafiltration (CVVHDF) were compared in vitro [5].
  • The increased urea and creatinine removal did not result in lower pretreatment serum concentrations in the hemodiafiltration group [6].
  • Resistance to intercompartmental mass transfer limits beta2-microglobulin removal by post-dilution hemodiafiltration [7].
  • In contrast, the clearance of protein-bound solutes relative to urea increased when hemodiafiltration was performed using a larger filter and increasing Q(d) to 300 mL/min while Q(p) was lowered to 50 mL/min [8].
  • RESULTS: A mean QS of 134 +/- 20 mL/min (mean FF = 0.65) was attained in post-HDF, and up to 307 +/- 41 mL/min (mean FF = 0.69) in mixed hemodiafiltration [9].

Chemical compound and disease context of Hemodiafiltration


Biological context of Hemodiafiltration


Anatomical context of Hemodiafiltration


Associations of Hemodiafiltration with chemical compounds

  • To determine bicarbonate, acetate, lactate and total buffer flux, mass balance studies were performed in patients treated with hemodiafiltration using four different combinations of dialysate and substitution fluids [22].
  • Pharmacokinetics of cefepime during continuous venovenous hemodiafiltration [23].
  • In mixed hemodiafiltration, a newly developed feedback system automatically maintained the transmembrane pressure (TMP) within its highest range of safety (250 to 300 mm Hg) at constant QUF, while ensuring the maximum FF by splitting infusion between pre- and postdilution [9].
  • CONCLUSION: Continuous venovenous hemodiafiltration is effective in removing ganciclovir from the blood [24].
  • Lithium poisoning treated by high-performance continuous arteriovenous and venovenous hemodiafiltration [25].

Gene context of Hemodiafiltration


Analytical, diagnostic and therapeutic context of Hemodiafiltration


  1. Urea removal during continuous hemodiafiltration. Frankenfield, D.C., Reynolds, H.N., Wiles, C.E., Badellino, M.M., Siegel, J.H. Crit. Care Med. (1994) [Pubmed]
  2. Lactic acidosis treated with continuous hemodiafiltration and regional citrate anticoagulation. Kirschbaum, B., Galishoff, M., Reines, H.D. Crit. Care Med. (1992) [Pubmed]
  3. N-acetylprocainamide intoxication with torsade de pointes treated by high dialysate flow rate continuous arteriovenous hemodiafiltration. Leblanc, M., Pichette, V., Madore, F., Ouimet, D., Geadah, D., Cardinal, J. Crit. Care Med. (1995) [Pubmed]
  4. Effect of bicarbonate and lactate buffer on glucose and lactate metabolism during hemodiafiltration in patients with multiple organ failure. Bollmann, M.D., Revelly, J.P., Tappy, L., Berger, M.M., Schaller, M.D., Cayeux, M.C., Martinez, A., Chioléro, R.L. Intensive care medicine. (2004) [Pubmed]
  5. In vitro comparison of the molecular adsorbent recirculation system (MARS) and single-pass albumin dialysis (SPAD). Sauer, I.M., Goetz, M., Steffen, I., Walter, G., Kehr, D.C., Schwartlander, R., Hwang, Y.J., Pascher, A., Gerlach, J.C., Neuhaus, P. Hepatology (2004) [Pubmed]
  6. A comparison of on-line hemodiafiltration and high-flux hemodialysis: a prospective clinical study. Ward, R.A., Schmidt, B., Hullin, J., Hillebrand, G.F., Samtleben, W. J. Am. Soc. Nephrol. (2000) [Pubmed]
  7. Resistance to intercompartmental mass transfer limits beta2-microglobulin removal by post-dilution hemodiafiltration. Ward, R.A., Greene, T., Hartmann, B., Samtleben, W. Kidney Int. (2006) [Pubmed]
  8. The clearance of protein-bound solutes by hemofiltration and hemodiafiltration. Meyer, T.W., Walther, J.L., Pagtalunan, M.E., Martinez, A.W., Torkamani, A., Fong, P.D., Recht, N.S., Robertson, C.R., Hostetter, T.H. Kidney Int. (2005) [Pubmed]
  9. On-line mixed hemodiafiltration with a feedback for ultrafiltration control: effect on middle-molecule removal. Pedrini, L.A., De Cristofaro, V. Kidney Int. (2003) [Pubmed]
  10. Pharmacokinetics and the most suitable dosing regimen of fluconazole in critically ill patients receiving continuous hemodiafiltration. Yagasaki, K., Gando, S., Matsuda, N., Kameue, T., Ishitani, T., Hirano, T., Iseki, K. Intensive care medicine. (2003) [Pubmed]
  11. Characteristics of an albumin dialysate hemodiafiltration system for the clearance of unconjugated bilirubin. Awad, S.S., Rich, P.B., Kolla, S., Younger, J.G., Reickert, C.A., Downing, V.P., Bartlett, R.H. ASAIO journal (American Society for Artificial Internal Organs : 1992) (1997) [Pubmed]
  12. Linezolid clearance during continuous venovenous hemodiafiltration: a case report. Kraft, M.D., Pasko, D.A., DePestel, D.D., Ellis, J.J., Peloquin, C.A., Mueller, B.A. Pharmacotherapy (2003) [Pubmed]
  13. Phosphodiesterase III inhibitor olprinone chlorate is not significantly removed by continuous venovenous hemodiafiltration. Amenomori, H., Sasaki, S., Hiraoka, K., Morimoto, Y., Gando, S., Kemmotsu, O. ASAIO journal (American Society for Artificial Internal Organs : 1992) (2000) [Pubmed]
  14. Case report: requirement of supplemental morphine during sedation with propofol in a critically ill patient undergoing hemodiafiltration. Imperatore, F., Marsilia, P.F., Munciello, F., Liguori, G., Borrelli, L.M., Gatta, G., Martino, A., Occhiochiuso, L. MedGenMed [electronic resource] : Medscape general medicine. (2003) [Pubmed]
  15. Pharmacokinetics of isepamicin during continuous venovenous hemodiafiltration. Breilh, D., Allaouchiche, B., Jaumain, H., Boulétreau, P., Chassard, D., Malbec, I., Ducint, D., Saux, M.C. Antimicrob. Agents Chemother. (1999) [Pubmed]
  16. New Method for Phosphate Kinetics Estimation during Hemodialysis and On-Line Hemodiafiltration with Endogenous Reinfusion. Bolasco, P., Ghezzi, P.M., Ferrara, R., Cogoni, G., Cadinu, F., Casu, D., Murtas, S. Blood Purif. (2006) [Pubmed]
  17. Inflammatory response to cardiac bypass in ewe fetuses: effects of steroid administration or continuous hemodiafiltration. Carotti, A., Emma, F., Picca, S., Iannace, E., Albanese, S.B., Grigioni, M., Meo, F., Sciarra, M., Di Donato, R.M. J. Thorac. Cardiovasc. Surg. (2003) [Pubmed]
  18. Mechanisms of acid-base homeostasis in acetate and bicarbonate dialysis, lactate hemofiltration and hemodiafiltration. Panichi, V., Parrini, M., Bianchi, A.M., Andreini, B., Cirami, C., Finato, V., Palla, R. The International journal of artificial organs. (1994) [Pubmed]
  19. Continuous venous hemodiafiltration with trisodium citrate anticoagulation in cardiac surgery patients. Urquhart, G., Rebeyka, D. Dynamics (Pembroke, Ont.) (2000) [Pubmed]
  20. Production of cytokines in hemodialysis. Tetta, C., Camussi, G., Turello, E., Salomone, M., Aimo, G., Priolo, G., Segoloni, G., Vercellone, A. Blood Purif. (1990) [Pubmed]
  21. Removal of acyclovir during continuous veno-venous hemodialysis and hemodiafiltration with high-efficiency membranes. Khajehdehi, P., Jamal, J.A., Bastani, B. Clin. Nephrol. (2000) [Pubmed]
  22. Effect of dialysate and substitution fluid buffer on buffer flux in hemodiafiltration. Feriani, M., Ronco, C., Biasioli, S., Bragantini, L., La Greca, G. Kidney Int. (1991) [Pubmed]
  23. Pharmacokinetics of cefepime during continuous venovenous hemodiafiltration. Allaouchiche, B., Breilh, D., Jaumain, H., Gaillard, B., Renard, S., Saux, M.C. Antimicrob. Agents Chemother. (1997) [Pubmed]
  24. Pharmacokinetics and clearance of ganciclovir during continuous hemodiafiltration. Gando, S., Kameue, T., Nanzaki, S., Hayakawa, T., Nakanishi, Y. Crit. Care Med. (1998) [Pubmed]
  25. Lithium poisoning treated by high-performance continuous arteriovenous and venovenous hemodiafiltration. Leblanc, M., Raymond, M., Bonnardeaux, A., Isenring, P., Pichette, V., Geadah, D., Quimet, D., Ethier, J., Cardinal, J. Am. J. Kidney Dis. (1996) [Pubmed]
  26. Radioimmunoassay for human parathyroid hormone for differentiation between patients with hypoparathyroidism, hyperparathyroidism and normals. Streibl, W., Minne, H., Raue, F., Ziegler, R. Horm. Metab. Res. (1979) [Pubmed]
  27. Osteoprotegerin and bone mineral density in hemodiafiltration patients. Crisafulli, A., Romeo, A., Floccari, F., Aloisi, E., Atteritano, M., Cincotta, M., Aloisi, C., Pizzoleo, M.A., Ruello, A., Artemisia, A., Valenti, A., Frisina, N., Teti, D., Buemi, M. Renal failure. (2005) [Pubmed]
  28. Improved iron utilization and reduced erythropoietin resistance by on-line hemodiafiltration. Lin, C.L., Huang, C.C., Yu, C.C., Wu, C.H., Chang, C.T., Hsu, H.H., Hsu, P.Y., Yang, C.W. Blood Purif. (2002) [Pubmed]
  29. Can the clearance of tumor necrosis factor alpha and interleukin 6 be enhanced using an albumin dialysate hemodiafiltration system? Awad, S.S., Sawada, S., Soldes, O.S., Rich, P.B., Klein, R., Alarcon, W.H., Wang, S.C., Bartlett, R.H. ASAIO journal (American Society for Artificial Internal Organs : 1992) (1999) [Pubmed]
  30. The post-hemodialysis rebound: predicting and quantifying its effect on Kt/V. Tattersall, J.E., DeTakats, D., Chamney, P., Greenwood, R.N., Farrington, K. Kidney Int. (1996) [Pubmed]
  31. Use of peritoneal dialysis, continuous arteriovenous hemofiltration, and continuous arteriovenous hemodiafiltration for removal of ammonium chloride and glutamine in rabbits. Semama, D.S., Huet, F., Gouyon, J.B., Lallemant, C., Desgres, J. J. Pediatr. (1995) [Pubmed]
  32. Improvement of hepatorenal syndrome with extracorporeal albumin dialysis MARS: results of a prospective, randomized, controlled clinical trial. Mitzner, S.R., Stange, J., Klammt, S., Risler, T., Erley, C.M., Bader, B.D., Berger, E.D., Lauchart, W., Peszynski, P., Freytag, J., Hickstein, H., Loock, J., Löhr, J.M., Liebe, S., Emmrich, J., Korten, G., Schmidt, R. Liver Transpl. (2000) [Pubmed]
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