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Chemical Compound Review

Isepamicin     3-amino-N-[5-amino-4-[6- (aminomethyl)-3,4...

Synonyms: Isepamicina, Isepamicine, Isepamicinum, HAPA-B, SureCN152418, ...
 
 
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Disease relevance of HAPA-gentamycin B

 

High impact information on HAPA-gentamycin B

 

Chemical compound and disease context of HAPA-gentamycin B

 

Biological context of HAPA-gentamycin B

 

Anatomical context of HAPA-gentamycin B

 

Associations of HAPA-gentamycin B with other chemical compounds

 

Gene context of HAPA-gentamycin B

 

Analytical, diagnostic and therapeutic context of HAPA-gentamycin B

References

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  7. Comparison of in vitro activity of Sch 21420, a gentamicin B derivative, with those of amikacin, gentamicin, netilmicin, sisomicin, and tobramycin. Thornsberry, C., Barry, A.L., Jones, R.N., Baker, C.N., Badal, R.E., Packer, R.R. Antimicrob. Agents Chemother. (1980) [Pubmed]
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  11. Pharmacokinetics of isepamicin following a single administration by intravenous infusion or intramuscular injections. Radwanski, E., Batra, V., Cayen, M., Korduba, C., Cutler, D., Affrime, M., Nomeir, A., Lin, C.C. Antimicrob. Agents Chemother. (1997) [Pubmed]
  12. Solution studies of isepamicin and conformational comparisons between isepamicin and butirosin A when bound to an aminoglycoside 6'-N-acetyltransferase determined by NMR spectroscopy. DiGiammarino, E.L., Draker, K.A., Wright, G.D., Serpersu, E.H. Biochemistry (1998) [Pubmed]
  13. Pharmacokinetics and metabolism of 14C-isepamicin in humans following intravenous administration. Lin, C., Korduba, C., Affrime, M., Radwanski, E., Nomeir, A., Batra, V., Cutler, D., Cayen, M.N. Antimicrob. Agents Chemother. (1995) [Pubmed]
  14. Isepamicin (SCH 21420, 1-N-HAPA gentamicin B): microbiological characteristics including antimicrobial potency of spectrum of activity. Jones, R.N. Journal of chemotherapy (Florence, Italy) (1995) [Pubmed]
  15. Effect of isepamicin dosing scheme on concentration in cochlear tissue. Govaerts, P.J., Claes, J., Van de Heyning, P.H., Derde, M.P., Kaufman, L., Marquet, J.F., De Broe, M.E. Antimicrob. Agents Chemother. (1991) [Pubmed]
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  17. Resistance to amikacin and isepamicin in rabbits with experimental endocarditis of an aac(6')-Ib-bearing strain of Klebsiella pneumoniae susceptible in vitro. Caulin, E., Coutrot, A., Carbon, C., Collatz, E. Antimicrob. Agents Chemother. (1996) [Pubmed]
  18. In vitro activity of Sch 21420, derivative of gentamicin B, compared to that of amikacin. Kabins, S.A., Nathan, C. Antimicrob. Agents Chemother. (1978) [Pubmed]
  19. In vitro activities of tigecycline, ertapenem, isepamicin, and other antimicrobial agents against clinically isolated organisms in Taiwan. Cheng, N.C., Hsueh, P.R., Liu, Y.C., Shyr, J.M., Huang, W.K., Teng, L.J., Liu, C.Y. Microb. Drug Resist. (2005) [Pubmed]
  20. Rabbits treated with chronic isepamicin are resistant to mivacurium and rocuronium. Kim, K.S., Shim, J.C., Jun, J.H., Lee, K.H., Chung, C.W. Anesth. Analg. (1999) [Pubmed]
  21. Effects of some antibiotics on activity of glucose-6-phosphate dehydrogenase from human erythrocytes in vitro and effect of isepamicin sulfate on activities of antioxidant enzymes in rat erythrocytes. Ozmen, I., Küfrevioğlu, O.I., Gul, M. Drug and chemical toxicology. (2005) [Pubmed]
  22. Isepamicin disposition in subjects with various degrees of renal function. Halstenson, C.E., Kelloway, J.S., Affrime, M.B., Lin, C.C., Teal, M.A., Shapiro, B.E., Awni, W.M. Antimicrob. Agents Chemother. (1991) [Pubmed]
  23. Population pharmacokinetic study of isepamicin with intensive care unit patients. Tod, M., Padoin, C., Minozzi, C., Cougnard, J., Petitjean, O. Antimicrob. Agents Chemother. (1996) [Pubmed]
  24. Pharmacokinetics of intravenously administered isepamicin in men. Lin, C.C., Radwanski, E., Korduba, C., Cayen, M., Affrime, M. Antimicrob. Agents Chemother. (1995) [Pubmed]
 
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