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Disease relevance of Galactorrhea


Psychiatry related information on Galactorrhea


High impact information on Galactorrhea


Chemical compound and disease context of Galactorrhea


Biological context of Galactorrhea

  • After medical therapy normal menstruation continued, galactorrhea recurred intermittently, and the prolactin level rose again and remained in the approximately 36-micrograms/L range [16].
  • Plasma LH, FSH and prolactin secretory patterns were derived from the measurement of 20-min interval plasma samples obtained during a complete 24-h period in a patient with persistent postpartum amenorrhea and galactorrhea (Chiari-Frommel syndrome), before and after clomiphene citrate therapy [17].
  • To investigate these differences in PRL secretion, we have characterized the molecular forms of circulating PRL in postpartum women during breastfeeding (n = 5) and sleep (n = 5) and in eumenorrheic women with galactorrhea (n = 5) after TRH stimulation (n = 4), metaclopramide infusion (n = 5), and morphine administration (n = 2) [18].
  • Thirty infertile patients with ovulation defects and galactorrhea conceived after medical therapy: four after clomiphene stimulation (with or without hCG) and 26 after receiving CB-154 (2-Br-alpha-ergocryptine or bromergocryptine) [19].
  • Menses returned in 31 of 32 women and galactorrhea disappeared in 25 of 31 women with preoperative serum prolactin levels below 200 ng/ml; conversely, menses returned in only three of nine women and lactation ceased in one of six women with preoperative serum prolactin concentrations above 200 ng/ml [20].

Anatomical context of Galactorrhea


Gene context of Galactorrhea


Analytical, diagnostic and therapeutic context of Galactorrhea


  1. Galactorrhea: a study of 235 cases, including 48 with pituitary tumors. Kleinberg, D.L., Noel, G.L., Frantz, A.G. N. Engl. J. Med. (1977) [Pubmed]
  2. Arteriovenous shunting and cholestasis in hepatic hemangiomatosis associated with metoclopramide. Feurle, G.E. Gastroenterology (1990) [Pubmed]
  3. First reported pediatric case of systemic lupus erythematosus associated with prolactinoma. Reuman, P.D. Arthritis Rheum. (2004) [Pubmed]
  4. Characterization of a pituitary stone. von Westarp, C., Weir, B.K., Shnitka, T.K. Am. J. Med. (1980) [Pubmed]
  5. Hypoglycemia-induced prolactin release. May, P.B., Burrow, G.N., Kayne, R.D., Donabedian, R.K. Arch. Intern. Med. (1978) [Pubmed]
  6. The relationship between prolactin response and clinical efficacy of risperidone in acute psychotic inpatients. Lee, B.H., Kim, Y.K. Prog. Neuropsychopharmacol. Biol. Psychiatry (2006) [Pubmed]
  7. Recurrence of hyperprolactinemia after selective transsphenoidal adenomectomy in women with prolactinoma. Serri, O., Rasio, E., Beauregard, H., Hardy, J., Somma, M. N. Engl. J. Med. (1983) [Pubmed]
  8. Hyperprolactinemia, galactorrhea, and atenolol. Lee, S.T. Ann. Intern. Med. (1992) [Pubmed]
  9. Verapamil-induced hyperprolactinemia and galactorrhea. Gluskin, L.E., Strasberg, B., Shah, J.H. Ann. Intern. Med. (1981) [Pubmed]
  10. Galactorrhea induced by sertraline. Bronzo, M.R., Stahl, S.M. The American journal of psychiatry. (1993) [Pubmed]
  11. Autonomous hyperprolactinemia in tuberous sclerosis. Bloomgarden, Z.T., McLean, G.W., Rabin, D. Arch. Intern. Med. (1981) [Pubmed]
  12. Estrogen-induced galactorrhea in man. Draznin, B., Maman, A. Arch. Intern. Med. (1979) [Pubmed]
  13. Primary hypothyroidism and galactorrhea. Onishi, T., Miyai, K., Aono, T., Shioji, T., Yamamoto, T. Am. J. Med. (1977) [Pubmed]
  14. Galactorrhea associated with molindone. Wesp, C.E., Annitto, W., Feinsod, R. The American journal of psychiatry. (1979) [Pubmed]
  15. Hyperprolactinemia and galactorrhea: spontaneous versus iatrogenic hypothyroidism. Contreras, P., Generini, G., Michelsen, H., Pumarino, H., Campino, C. J. Clin. Endocrinol. Metab. (1981) [Pubmed]
  16. Ectopic hyperprolactinemia resulting from an ovarian teratoma. Kallenberg, G.A., Pesce, C.M., Norman, B., Ratner, R.E., Silvergerg, S.G. JAMA (1990) [Pubmed]
  17. Twenty-four-hour secretory patterns of gonadotropins and prolactin in a case of Chiari-Frommel syndrome. Kapen, S., Boyar, R., Freeman, R., Frantz, A., Hellman, L., Weitzman, E.D. J. Clin. Endocrinol. Metab. (1975) [Pubmed]
  18. Differential release of prolactin variants in postpartum and early follicular phase women. Liu, J.H., Lee, D.W., Markoff, E. J. Clin. Endocrinol. Metab. (1990) [Pubmed]
  19. The effect of pregnancy on suspected pituitary adenomas after conservative management of ovulation defects associated with galactorrhea. Shewchuk, A.B., Adamson, G.D., Lessard, P., Ezrin, C. Am. J. Obstet. Gynecol. (1980) [Pubmed]
  20. Prolactin-secreting pituitary adenomas in women. II. Menstrual function, pituitary reserves, and prolactin production following microsurgical removal. Keye, W.R., Chang, R.J., Monroe, S.E., Wilson, C.B., Jaffe, R.B. Am. J. Obstet. Gynecol. (1979) [Pubmed]
  21. Prolactin-secreting pituitary adenomas. III. Frequency and diagnosis in amenorrhea-galactorrhea. Keye, W.R., Chang, R.J., Wilson, C.B., Jaffe, R.B. JAMA (1980) [Pubmed]
  22. Postburn galactorrhea with refractory hypertrophic scars: role of obesity under scrutiny. Saraiya, H. The Journal of burn care & rehabilitation. (2003) [Pubmed]
  23. Hyperprolactinemic galactorrhea in a patient with Hodgkin's disease and intense pruritus. Cooper, D.L., Gilliam, A.C., Perez, M.I. South. Med. J. (1993) [Pubmed]
  24. Cervical mucus prolactin levels in normal fertile and infertile women. Shaarawy, M., Darwish, N.A., Nagui, A.R., Ezzat, R.A. Asia-Oceania journal of obstetrics and gynaecology / AOFOG. (1989) [Pubmed]
  25. Dynamic evaluation of growth hormone (GH) and prolactin (hPRL) secretion in active acromegaly with high and low GH output. Tolis, G., Kovacs, L., Friesen, H., Martin, J.B. Acta Endocrinol. (1975) [Pubmed]
  26. Novel features of tumors that secrete both growth hormone and prolactin in acromegaly. Nyquist, P., Laws, E.R., Elliott, E. Neurosurgery (1994) [Pubmed]
  27. Ziprasidone-induced galactorrhea: a case report. Kopecek, M., Bares, M., Mohr, P. Neuro Endocrinol. Lett. (2005) [Pubmed]
  28. Autoantibody to human prolactin in patients with idiopathic hyperprolactinemia. Hattori, N., Ishihara, T., Ikekubo, K., Moridera, K., Hino, M., Kurahachi, H. J. Clin. Endocrinol. Metab. (1992) [Pubmed]
  29. Composition of breast fluid of a man with galactorrhea and hyperprolactinaemia. Kulski, J.K., Hartmann, P.E., Gutteridge, D.H. J. Clin. Endocrinol. Metab. (1981) [Pubmed]
  30. The association of Ga-67 and lactoferrin. Hoffer, P.B., Huberty, J., Khayam-Bashi, H. J. Nucl. Med. (1977) [Pubmed]
  31. Hypothalamic, pituitary and thyroid dysfunction after radiotherapy to the head and neck. Samaan, N.A., Vieto, R., Schultz, P.N., Maor, M., Meoz, R.T., Sampiere, V.A., Cangir, A., Ried, H.L., Jesse, R.H. Int. J. Radiat. Oncol. Biol. Phys. (1982) [Pubmed]
  32. Breast examination does not elevate serum prolactin. Jarrell, J., Franks, S., McInnes, R., Gemayel, K., Guyda, H., Arronet, G.H., Naftolin, F. Fertil. Steril. (1980) [Pubmed]
  33. Menstrual disturbances in chronic renal failure. Morley, J.E., Distiller, L.A., Epstein, S., Katz, M., Gold, C., Sagel, J., Kaye, G., Pokroy, M., Kalk, J. Horm. Metab. Res. (1979) [Pubmed]
  34. Breast engorgement and galactorrhea during magnesium sulfate treatment of preterm labor. Lurie, S., Rotmensch, S., Feldman, N., Glezerman, M. American journal of perinatology. (2002) [Pubmed]
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