The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Porcine respiratory and reproductive syndrome virus

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Porcine respiratory and reproductive syndrome virus

 

High impact information on Porcine respiratory and reproductive syndrome virus

 

Chemical compound and disease context of Porcine respiratory and reproductive syndrome virus

  • GP(3), which was identified as a minor structural protein of European types of PRRSV, did not bind to heparin [9].
  • Analysis of infection kinetics showed that PRRSV attachment to heparan sulfate occurs early in infection [9].
  • Ceftiofur treatment was the only regimen that significantly (P < 0. 05) reduced mortality associated with PRRSV and S. suis coinfection [10].
  • RT-PCR was found to be more sensitive than indirect immunofluorescence assay for detection of PRRSV in tissues from experimentally infected pigs and as sensitive as virus isolation in PAM, especially when combined with Southern blotting with the digoxigenin-labeled N probe and chemiluminescence detection [11].
  • The data suggest that, in addition to homodimerization, the PRRSV N protein may also undergo heterodimerization with another structural protein using cysteine 90 and that the N protein heterodimerization is essential for PRRSV infectivity [12].
 

Biological context of Porcine respiratory and reproductive syndrome virus

 

Anatomical context of Porcine respiratory and reproductive syndrome virus

 

Gene context of Porcine respiratory and reproductive syndrome virus

 

Analytical, diagnostic and therapeutic context of Porcine respiratory and reproductive syndrome virus

References

  1. Influence of N-linked glycosylation of porcine reproductive and respiratory syndrome virus GP5 on virus infectivity, antigenicity, and ability to induce neutralizing antibodies. Ansari, I.H., Kwon, B., Osorio, F.A., Pattnaik, A.K. J. Virol. (2006) [Pubmed]
  2. Colocalization and interaction of the porcine arterivirus nucleocapsid protein with the small nucleolar RNA-associated protein fibrillarin. Yoo, D., Wootton, S.K., Li, G., Song, C., Rowland, R.R. J. Virol. (2003) [Pubmed]
  3. Envelope protein requirements for the assembly of infectious virions of porcine reproductive and respiratory syndrome virus. Wissink, E.H., Kroese, M.V., van Wijk, H.A., Rijsewijk, F.A., Meulenberg, J.J., Rottier, P.J. J. Virol. (2005) [Pubmed]
  4. Identification of major differences in the nucleocapsid protein genes of a Québec strain and European strains of porcine reproductive and respiratory syndrome virus. Mardassi, H., Mounir, S., Dea, S. J. Gen. Virol. (1994) [Pubmed]
  5. Interferon-alpha response to swine arterivirus (PoAV), the porcine reproductive and respiratory syndrome virus. Albina, E., Carrat, C., Charley, B. J. Interferon Cytokine Res. (1998) [Pubmed]
  6. Porcine arterivirus infection of alveolar macrophages is mediated by sialic acid on the virus. Delputte, P.L., Nauwynck, H.J. J. Virol. (2004) [Pubmed]
  7. Involvement of sialoadhesin in entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages. Vanderheijden, N., Delputte, P.L., Favoreel, H.W., Vandekerckhove, J., Van Damme, J., van Woensel, P.A., Nauwynck, H.J. J. Virol. (2003) [Pubmed]
  8. Homo-oligomerization of the porcine reproductive and respiratory syndrome virus nucleocapsid protein and the role of disulfide linkages. Wootton, S.K., Yoo, D. J. Virol. (2003) [Pubmed]
  9. Involvement of the matrix protein in attachment of porcine reproductive and respiratory syndrome virus to a heparinlike receptor on porcine alveolar macrophages. Delputte, P.L., Vanderheijden, N., Nauwynck, H.J., Pensaert, M.B. J. Virol. (2002) [Pubmed]
  10. Efficacy of antimicrobial treatments and vaccination regimens for control of porcine reproductive and respiratory syndrome virus and Streptococcus suis coinfection of nursery pigs. Halbur, P., Thanawongnuwech, R., Brown, G., Kinyon, J., Roth, J., Thacker, E., Thacker, B. J. Clin. Microbiol. (2000) [Pubmed]
  11. Detection of porcine reproductive and respiratory syndrome virus and efficient differentiation between Canadian and European strains by reverse transcription and PCR amplification. Mardassi, H., Wilson, L., Mounir, S., Dea, S. J. Clin. Microbiol. (1994) [Pubmed]
  12. A DNA-launched reverse genetics system for porcine reproductive and respiratory syndrome virus reveals that homodimerization of the nucleocapsid protein is essential for virus infectivity. Lee, C., Calvert, J.G., Welch, S.K., Yoo, D. Virology (2005) [Pubmed]
  13. Cysteine residues of the porcine reproductive and respiratory syndrome virus small envelope protein are non-essential for virus infectivity. Lee, C., Yoo, D. J. Gen. Virol. (2005) [Pubmed]
  14. A 10-kDa structural protein of porcine reproductive and respiratory syndrome virus encoded by ORF2b. Wu, W.H., Fang, Y., Farwell, R., Steffen-Bien, M., Rowland, R.R., Christopher-Hennings, J., Nelson, E.A. Virology (2001) [Pubmed]
  15. An RNA helicase, RHIV -1, induced by porcine reproductive and respiratory syndrome virus (PRRSV) is mapped on porcine chromosome 10q13. Zhang, X., Wang, C., Schook, L.B., Hawken, R.J., Rutherford, M.S. Microb. Pathog. (2000) [Pubmed]
  16. Antigenic differences between European and American isolates of porcine reproductive and respiratory syndrome virus (PRRSV) are encoded by the carboxyterminal portion of viral open reading frame 3. Katz, J.B., Shafer, A.L., Eernisse, K.A., Landgraf, J.G., Nelson, E.A. Vet. Microbiol. (1995) [Pubmed]
  17. Comparison of the structural protein coding sequences of the VR-2332 and Lelystad virus strains of the PRRS virus. Murtaugh, M.P., Elam, M.R., Kakach, L.T. Arch. Virol. (1995) [Pubmed]
  18. Effect of heparin on infection of cells by porcine reproductive and respiratory syndrome virus. Jusa, E.R., Inaba, Y., Kouno, M., Hirose, O. Am. J. Vet. Res. (1997) [Pubmed]
  19. Immune responses and protection by vaccine and various vaccine adjuvant candidates to virulent porcine reproductive and respiratory syndrome virus. Charerntantanakul, W., Platt, R., Johnson, W., Roof, M., Vaughn, E., Roth, J.A. Vet. Immunol. Immunopathol. (2006) [Pubmed]
  20. Detection of porcine reproductive and respiratory syndrome virus in cell cultures and formalin-fixed tissues by in situ hybridization using a digoxigenin-labeled probe. Larochelle, R., Mardassi, H., Dea, S., Magar, R. J. Vet. Diagn. Invest. (1996) [Pubmed]
  21. Detection of economically important viruses in boar semen by quantitative RealTime PCR technology. van Rijn, P.A., Wellenberg, G.J., Hakze-van der Honing, R., Jacobs, L., Moonen, P.L., Feitsma, H. J. Virol. Methods (2004) [Pubmed]
  22. Beta-glucan enhancement of T cell IFNgamma response in swine. Xiao, Z., Trincado, C.A., Murtaugh, M.P. Vet. Immunol. Immunopathol. (2004) [Pubmed]
  23. The dimer interface of the SARS coronavirus nucleocapsid protein adapts a porcine respiratory and reproductive syndrome virus-like structure. Chang, C.K., Sue, S.C., Yu, T.H., Hsieh, C.M., Tsai, C.K., Chiang, Y.C., Lee, S.J., Hsiao, H.H., Wu, W.J., Chang, C.F., Huang, T.H. FEBS Lett. (2005) [Pubmed]
  24. Upregulation of IL-10 gene expression in porcine peripheral blood mononuclear cells by porcine reproductive and respiratory syndrome virus. Suradhat, S., Thanawongnuwech, R., Poovorawan, Y. J. Gen. Virol. (2003) [Pubmed]
  25. Identification and characterization of a sixth structural protein of Lelystad virus: the glycoprotein GP2 encoded by ORF2 is incorporated in virus particles. Meulenberg, J.J., Petersen-den Besten, A. Virology (1996) [Pubmed]
  26. Immune response in pigs vaccinated with plasmid DNA encoding ORF5 of porcine reproductive and respiratory syndrome virus. Pirzadeh, B., Dea, S. J. Gen. Virol. (1998) [Pubmed]
  27. Genetic diversity and phylogenetic analysis of glycoprotein 5 of European-type porcine reproductive and respiratory virus strains in Spain. Mateu, E., Martín, M., Vidal, D. J. Gen. Virol. (2003) [Pubmed]
  28. A molecular clock dates the common ancestor of European-type porcine reproductive and respiratory syndrome virus at more than 10 years before the emergence of disease. Forsberg, R., Oleksiewicz, M.B., Petersen, A.M., Hein, J., Bøtner, A., Storgaard, T. Virology (2001) [Pubmed]
  29. GP5 ectodomain epitope of porcine reproductive and respiratory syndrome virus, strain Lelystad virus. Plagemann, P.G. Virus Res. (2004) [Pubmed]
  30. Deciphering the involvement of innate immune factors in the development of the host response to PRRSV vaccination. Royaee, A.R., Husmann, R.J., Dawson, H.D., Calzada-Nova, G., Schnitzlein, W.M., Zuckermann, F.A., Lunney, J.K. Vet. Immunol. Immunopathol. (2004) [Pubmed]
  31. Comparison of virus isolation, reverse transcription-polymerase chain reaction, immunohistochemistry, and in situ hybridization for the detection of porcine reproductive and respiratory syndrome virus from naturally aborted fetuses and stillborn piglets. Cheon, D.S., Chae, C. J. Vet. Diagn. Invest. (2000) [Pubmed]
 
WikiGenes - Universities