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MeSH Review


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Disease relevance of Marmota


High impact information on Marmota


Chemical compound and disease context of Marmota


Biological context of Marmota


Anatomical context of Marmota

  • These results provide indirect evidence that the pancreatic A and B cells of hibernating marmots continue to function in order to help regulate plasma glucose concentration [16].
  • Real-time polymerase chain reaction assays for leukocyte CD and cytokine mRNAs of the Eastern woodchuck (Marmota monax) [17].
  • Blood samples were obtained in the field by femoral vein puncture in bushy-tailed woodrats (Neotoma cinerea) and yellow-bellied marmots (Marmota flaviventris) that had been injected intramuscularly with ketamine hydrochloride [18].

Associations of Marmota with chemical compounds

  • Circannual changes in serum testosterone concentrations of adult and yearling woodchucks (Marmota monax) [19].
  • Lobucavir (BMS-180194), a cyclobutyl-guanosine nucleoside analogue, effectively reduced WHV-viremia in chronically infected carrier woodchucks (Marmota monax) by daily per os treatment [20].
  • In this study, marmots fed a diet high in alpha-linolenic acid, with normal linoleic acid levels, had significantly (p < 0.05) more alpha-18:3 in their WAT and plasma unesterified fatty acids after 4 months than did marmots fed a control diet [21].
  • Ventilation was measured across a range of O2 consumption rates in four sciurid rodents: Tamias minimus (47 g), Spermophilus lateralis (189 g), S. beecheyi (531 g), and Marmota flaviventris juveniles (1054 g) and adults (2989 g) [22].
  • The effects of pentobarbital (30 mg/kg), urethan (2 g/kg), chloralose/urethan (50 mg/kg, 500 mg/kg), and thiobutabarbital (Inactin, 100 mg/kg) on the mean arterial pressure (BP) and heart period (HP) of Marmota flaviventris were examined [23].

Gene context of Marmota


  1. Nitrite and nitrosamine synthesis by hepatocytes isolated from normal woodchucks (Marmota monax) and woodchucks chronically infected with woodchuck hepatitis virus. Liu, R.H., Jacob, J.R., Tennant, B.C., Hotchkiss, J.H. Cancer Res. (1992) [Pubmed]
  2. Alpha-fetoprotein in the woodchuck model of hepadnavirus infection and disease: normal physiological patterns and responses to woodchuck hepatitis virus infection and hepatocellular carcinoma. Cote, P.J., Gerin, J.L., Tennant, B.C. Cancer Res. (1990) [Pubmed]
  3. Fat-cell mass, serum leptin and adiponectin changes during weight gain and loss in yellow-bellied marmots (Marmota flaviventris). Florant, G.L., Porst, H., Peiffer, A., Hudachek, S.F., Pittman, C., Summers, S.A., Rajala, M.W., Scherer, P.E. J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. (2004) [Pubmed]
  4. Interrelationships between body weight, food consumption and plasma thyroid hormone concentration cycles in the woodchuck, Marmota monax. Young, R.A. Comparative biochemistry and physiology. A, Comparative physiology. (1984) [Pubmed]
  5. Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors. Jacob, J.R., Sterczer, A., Toshkov, I.A., Yeager, A.E., Korba, B.E., Cote, P.J., Buendia, M.A., Gerin, J.L., Tennant, B.C. Hepatology (2004) [Pubmed]
  6. The geometry of the marmot (rodentia: sciuridae) mandible: phylogeny and patterns of morphological evolution. Cardini, A. Syst. Biol. (2003) [Pubmed]
  7. Melatonin profile in marmots: the influence of catecholamines, hibernation, and light. Florant, G., Green, R., Abel, T., Hartzell, S., Tamarkin, L., Brainard, G. J. Pineal Res. (1989) [Pubmed]
  8. Seasonal changes in serum thyroid hormone binding proteins in the woodchuck (Marmota monax). Young, R.A., Rajatanavin, R., Braverman, L.E., Tennant, B.C. Endocrinology (1986) [Pubmed]
  9. The estrous cycle of captive woodchucks (Marmota monax). Hikim, A.P., Woolf, A., Bartke, A., Amador, A.G. Biol. Reprod. (1991) [Pubmed]
  10. Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model. Jacob, J.R., Korba, B.E., Cote, P.J., Toshkov, I., Delaney, W.E., Gerin, J.L., Tennant, B.C. Antiviral Res. (2004) [Pubmed]
  11. Molecular cloning and characterization of major histocompatibility complex class I cDNAs from woodchuck (Marmota monax). Yang, D.L., Lu, M., Hao, L.J., Roggendorf, M. Tissue Antigens (2000) [Pubmed]
  12. Seasonal variations in circulating levels of progesterone and estradiol in unmated adult female woodchucks (Marmota monax) in captivity. Hikim, A.P., Amador, A.G., Woolf, A., Bartke, A., Gremillion-Smith, C. Life Sci. (1991) [Pubmed]
  13. Social thermoregulation during hibernation in alpine marmots (Marmota marmota). Arnold, W. J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. (1988) [Pubmed]
  14. Pharmacokinetics of cyclosporine in woodchucks and Pekin ducks. Vaden, S.L., Cullen, J.M., Riviere, J.E. J. Vet. Pharmacol. Ther. (1995) [Pubmed]
  15. Circannual changes in free thyroxine, prolactin, testes, and relative food intake in woodchucks, Marmota monax. Concannon, P.W., Castracane, V.D., Rawson, R.E., Tennant, B.C. Am. J. Physiol. (1999) [Pubmed]
  16. Pancreatic A and B cell stimulation in euthermic and hibernating marmots (Marmota flaviventris): effects of glucose and arginine administration. Florant, G.L., Hoo-Paris, R., Castex, C., Bauman, W.A., Sutter, B.C. J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. (1986) [Pubmed]
  17. Real-time polymerase chain reaction assays for leukocyte CD and cytokine mRNAs of the Eastern woodchuck (Marmota monax). Menne, S., Wang, Y., Butler, S.D., Gerin, J.L., Cote, P.J., Tennant, B.C. Vet. Immunol. Immunopathol. (2002) [Pubmed]
  18. Techniques for immobilizing and bleeding marmots and woodrats. Frase, B.A., Van Vuren, D. J. Wildl. Dis. (1989) [Pubmed]
  19. Circannual changes in serum testosterone concentrations of adult and yearling woodchucks (Marmota monax). Baldwin, B.H., Tennant, B.C., Reimers, T.J., Cowan, R.G., Concannon, P.W. Biol. Reprod. (1985) [Pubmed]
  20. Antiviral efficacy of lobucavir (BMS-180194), a cyclobutyl-guanosine nucleoside analogue, in the woodchuck (Marmota monax) model of chronic hepatitis B virus (HBV) infection. Genovesi, E.V., Lamb, L., Medina, I., Taylor, D., Seifer, M., Innaimo, S., Colonno, R.J., Clark, J.M. Antiviral Res. (2000) [Pubmed]
  21. The effect of a linseed oil diet on hibernation in yellow-bellied marmots (Marmota flaviventris). Hill, V.L., Florant, G.L. Physiol. Behav. (2000) [Pubmed]
  22. Ventilatory accommodation of changing oxygen demand in sciurid rodents. Chappell, M.A. J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. (1992) [Pubmed]
  23. Effects of anesthetics on cardiovascular responses of the marmot Marmota flaviventris. Zatzman, M.L., Thornhill, G.V. Cryobiology (1988) [Pubmed]
  24. Molecular characterization of CD28 and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) of woodchuck (Marmota monax). Yang, D., Roggendorf, M., Lu, M. Tissue Antigens (2003) [Pubmed]
  25. Seasonal changes in hormone-sensitive and lipoprotein lipase mRNA concentrations in marmot white adipose tissue. Wilson, B.E., Deeb, S., Florant, G.L. Am. J. Physiol. (1992) [Pubmed]
  26. Experimental La Crosse virus infection of red fox (Vulpes fulva), raccoon (Procyon lotor), opossum (Didelphis virginiana), and woodchuck (Marmota monax). Amundson, T.E., Yuill, T.M., DeFoliart, G.R. Am. J. Trop. Med. Hyg. (1985) [Pubmed]
  27. Plasma levels of atrial natriuretic factor in nonhibernating and hibernating marmots. Zatzman, M.L., Thornhill, G.V. Cryobiology (1989) [Pubmed]
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