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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Remission, Spontaneous

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Disease relevance of Remission, Spontaneous


High impact information on Remission, Spontaneous

  • Collectively, these findings indicate that Fas-mediated apoptosis/AICD plays a major role in the spontaneous remission after the initial acute inflammatory episode and represents an important intrinsic mechanism in regulation of autoimmune responses [6].
  • These data suggest that many patients with chronic type B hepatitis eventually have a spontaneous remission in clinical and biochemical evidence of active disease, usually heralded or accompanied by the disappearance of HBeAg and DNA polymerase [7].
  • Converting enzyme levels closely paralleled and occasionally antedated changes in clinical status in patients either undergoing spontaneous remission or being treated with prednisone [8].
  • Although improvement was temporally related to intrathecal IFN in 1 patient, it is not clear whether this was induced by IFN or a spontaneous remission [9].
  • We conclude that IL-4 plays an important role in modulating the severity of the encephalitogenic process, but does not by itself contribute to spontaneous remission from the disease [10].

Chemical compound and disease context of Remission, Spontaneous


Biological context of Remission, Spontaneous


Anatomical context of Remission, Spontaneous

  • Enhanced total IgE production may thus be a marker for activation of Th2 cells that produce lymphokines such as IL-4 and IL-10, factors that may be involved in the spontaneous remission process [19].
  • Therefore, we determined the density of calretinin-immunoreactive (CR) interneurons in the dt mutant at an age of maximum severity and after spontaneous remission of dystonia in comparison with age-matched nondystonic controls using an image analysis system and a stereologic counting method in a blinded fashion [20].

Associations of Remission, Spontaneous with chemical compounds


Gene context of Remission, Spontaneous


Analytical, diagnostic and therapeutic context of Remission, Spontaneous


  1. The spontaneous remission of juvenile idiopathic arthritis is characterized by CD30+ T cells directed to human heat-shock protein 60 capable of producing the regulatory cytokine interleukin-10. de Kleer, I.M., Kamphuis, S.M., Rijkers, G.T., Scholtens, L., Gordon, G., De Jager, W., Häfner, R., van de Zee, R., van Eden, W., Kuis, W., Prakken, B.J. Arthritis Rheum. (2003) [Pubmed]
  2. Cushing's disease in a patient with a 'nonfunctioning' pituitary tumor. Spontaneous development and remission. Gogel, E.L., Salber, P.R., Tyrrell, J.B., Rosenblum, M.L., Findling, J.W. Arch. Intern. Med. (1983) [Pubmed]
  3. Aminocaproic acid in prolonged hematuria of patients with sicklemia. Black, W.D., Hatch, F.E., Acchiardo, S. Arch. Intern. Med. (1976) [Pubmed]
  4. Anti-inflammatory cytokine release by alveolar macrophages in pulmonary sarcoidosis. Zissel, G., Homolka, J., Schlaak, J., Schlaak, M., Müller-Quernheim, J. Am. J. Respir. Crit. Care Med. (1996) [Pubmed]
  5. Natural history of adult-onset idiopathic torticollis. Jahanshahi, M., Marion, M.H., Marsden, C.D. Arch. Neurol. (1990) [Pubmed]
  6. Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis. Suvannavejh, G.C., Dal Canto, M.C., Matis, L.A., Miller, S.D. J. Clin. Invest. (2000) [Pubmed]
  7. Seroconversion from hepatitis B e antigen to antibody in chronic type B hepatitis. Hoofnagle, J.H., Dusheiko, G.M., Seeff, L.B., Jones, E.A., Waggoner, J.G., Bales, Z.B. Ann. Intern. Med. (1981) [Pubmed]
  8. Serum angiotensin-converting enzyme activity in evaluating the clinical course of sarcoidosis. DeRemee, R.A., Rohrbach, M.S. Ann. Intern. Med. (1980) [Pubmed]
  9. Intrathecal interferon in subacute sclerosing panencephalitis. Huttenlocher, P.R., Picchietti, D.L., Roos, R.P., Cashman, N.R., Horowitz, B., Horowitz, M.S. Ann. Neurol. (1986) [Pubmed]
  10. A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice. Falcone, M., Rajan, A.J., Bloom, B.R., Brosnan, C.F. J. Immunol. (1998) [Pubmed]
  11. Familial hyperinsulinism: successful conservative management. Horev, Z., Ipp, M., Levey, P., Daneman, D. J. Pediatr. (1991) [Pubmed]
  12. Lymphoma in patients with rheumatoid arthritis: what is the evidence of a link with methotrexate? Georgescu, L., Paget, S.A. Drug safety : an international journal of medical toxicology and drug experience. (1999) [Pubmed]
  13. Pheochromocytoma with remission following phentolamine-induced shock. Suzuki, T., Mori, C., Asakage, H., Akaza, H., Kawabe, K., Ueno, A., Koiso, K., Niijima, T. Urology (1984) [Pubmed]
  14. Bone morphogenetic protein-induced heterotopic bone in osteopetrosis. Miyazawa, K., Kawai, T., Urist, M.R. Clin. Orthop. Relat. Res. (1996) [Pubmed]
  15. The course of untreated mild T3 toxicosis. Stockigt, J.R., White, E.L., Petrou, S., Taft, P. Med. J. Aust. (1979) [Pubmed]
  16. Spontaneous remission in a patient with therapy-related myelodysplastic syndrome (t-MDS) with monosomy 7. Renneboog, B., Hansen, V., Heimann, P., De Mulder, A., Jannsen, F., Ferster, A. Br. J. Haematol. (1996) [Pubmed]
  17. Detection of residual BCR/ABL transcripts in chronic myeloid leukaemia patients in complete remission using the polymerase chain reaction and nested primers. Martiat, P., Maisin, D., Philippe, M., Ferrant, A., Michaux, J.L., Cassiman, J.J., Van den Berghe, H., Sokal, G. Br. J. Haematol. (1990) [Pubmed]
  18. Expression of nm23-H1 in hydatidiform mole and its relationship with the development of postmolar disease. Iwase, K., Okamoto, T., Nui, R., Mizutani, S. Gynecol. Obstet. Invest. (2001) [Pubmed]
  19. Collagen-induced arthritis in mice. Relationship of collagen-specific and total IgE synthesis to disease. Marcelletti, J.F., Ohara, J., Katz, D.H. J. Immunol. (1991) [Pubmed]
  20. Age-dependent alterations of striatal calretinin interneuron density in a genetic animal model of primary paroxysmal dystonia. Hamann, M., Sander, S.E., Richter, A. J. Neuropathol. Exp. Neurol. (2005) [Pubmed]
  21. Dynamics of glucose-induced insulin release during the spontaneous remission of streptozocin diabetes induced in the newborn rat. Portha, B., Kergoat, M. Diabetes (1985) [Pubmed]
  22. Insulin treatment improves the spontaneous remission of neonatal streptozotocin diabetes in the rat. Portha, B., Picon, L. Diabetes (1982) [Pubmed]
  23. Spontaneous remission of MAOI-induced anorgasmia. Nurnberg, H.G., Levine, P.E. The American journal of psychiatry. (1987) [Pubmed]
  24. Randomized study of nandrolone therapy for anemias due to bone marrow failure. Branda, R.F., Amsden, T.W., Jacob, H.S. Arch. Intern. Med. (1977) [Pubmed]
  25. A follow-up of 78 patients with Gilles de la Tourette's syndrome. Bruun, R.D., Shapiro, A.K., Shapiro, E., Sweet, R., Wayne, H., Solomon, G.E. The American journal of psychiatry. (1976) [Pubmed]
  26. Abnormal responses to vasoactive intestinal peptide and corticotropin releasing hormone during the spontaneous remission of Cushing's disease. Cannavò, S., Li Calzi, L., Aragona, A., Trimarchi, F. J. Endocrinol. Invest. (1988) [Pubmed]
  27. Expression of human telomerase reverse transcriptase, the catalytic subunit of telomerase, is associated with the development of persistent disease in complete hydatidiform moles. Amezcua, C.A., Bahador, A., Naidu, Y.M., Felix, J.C. Am. J. Obstet. Gynecol. (2001) [Pubmed]
  28. Neonatal convulsions and epileptic encephalopathy in an Italian family with a missense mutation in the fifth transmembrane region of KCNQ2. Dedek, K., Fusco, L., Teloy, N., Steinlein, O.K. Epilepsy Res. (2003) [Pubmed]
  29. Serum vascular endothelial growth factor as a possible prognostic indicator in sarcoidosis. Sekiya, M., Ohwada, A., Miura, K., Takahashi, S., Fukuchi, Y. Lung (2003) [Pubmed]
  30. Flutamide-induced acute hepatitis in advanced prostate cancer patients. Kraus, I., Vitezic, D., Oguic, R. International journal of clinical pharmacology and therapeutics. (2001) [Pubmed]
  31. Spontaneous remission of severe hyperparathyroidism in chronic renal failure. Charhon, S., Sellem, C., Meunier, P.J., Traeger, J. Nephron (1983) [Pubmed]
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