The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Atelectasis


High impact information on Atelectasis

  • CONCLUSIONS--The increased SPL causes compression atelectasis; this is prevented when PEEP to a given lung region is equal to or greater than the SPL [6].
  • Lung atelectasis in mutants correlates with reduced levels of NKX2.1 and surfactant [7].
  • However, Sim2 mutant mice die within 3 days of birth due to lung atelectasis and breathing failure [8].
  • Sulfuric acid produced diffuse pulmonary hyperinflation with areas of consolidation and atelectasis [9].
  • Right middle lobar atelectasis was induced in anesthesized rabbits (n = 18) by intraluminal obstruction of the bronchus after a 20-minute ventilation with 100% O2 [10].

Chemical compound and disease context of Atelectasis


Biological context of Atelectasis


Anatomical context of Atelectasis

  • Phrenic nerve stimulation during halothane anesthesia. Effects of atelectasis [21].
  • CONCLUSIONS: The dependent lung atelectasis produced by halothane anesthesia does not appear to be related to changes in the position of any single chest wall structure in these healthy young subjects, but rather to an interaction of several factors that remain to be identified [11].
  • We conclude that infiltration of the fascia with 0.25% bupivacaine at a dose of 2 ml/cm of incision is not effective in preventing postoperative atelectasis [22].
  • To test the relative sensitivity of serotonin and propranolol pulmonary extraction measurements to changes in pulmonary vascular surface, we sequentially subjected anaesthetized dogs to left upper lobe atelectasis, left lung atelectasis and left pulmonary artery occlusion [23].
  • Four of the seven patients had prolonged atelectasis of the left lower lobe and two had major vascular compression (pulmonary veins in the left lung in one and the inferior vena cava in another) [24].

Gene context of Atelectasis


Analytical, diagnostic and therapeutic context of Atelectasis


  1. Foxa2 is required for transition to air breathing at birth. Wan, H., Xu, Y., Ikegami, M., Stahlman, M.T., Kaestner, K.H., Ang, S.L., Whitsett, J.A. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  2. Bronchoalveolar lavage with KL4-surfactant in models of meconium aspiration syndrome. Cochrane, C.G., Revak, S.D., Merritt, T.A., Schraufstätter, I.U., Hoch, R.C., Henderson, C., Andersson, S., Takamori, H., Oades, Z.G. Pediatr. Res. (1998) [Pubmed]
  3. Syndrome of inappropriate antidiuretic hormone secretion in neonates with pneumothorax or atelectasis. Paxson, C.L., Stoerner, J.W., Denson, S.E., Adcock, E.W., Morriss, F.H. J. Pediatr. (1977) [Pubmed]
  4. Surfactant protein B corrects oxygen-induced pulmonary dysfunction in heterozygous surfactant protein B-deficient mice. Tokieda, K., Ikegami, M., Wert, S.E., Baatz, J.E., Zou, Y., Whitsett, J.A. Pediatr. Res. (1999) [Pubmed]
  5. Chronic pulmonary insufficiency of prematurity (CPIP). Krauss, A.N., Klain, D.B., Auld, P.A. Pediatrics (1975) [Pubmed]
  6. Regional effects and mechanism of positive end-expiratory pressure in early adult respiratory distress syndrome. Gattinoni, L., D'Andrea, L., Pelosi, P., Vitale, G., Pesenti, A., Fumagalli, R. JAMA (1993) [Pubmed]
  7. Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice. Nasonkin, I.O., Ward, R.D., Raetzman, L.T., Seasholtz, A.F., Saunders, T.L., Gillespie, P.J., Camper, S.A. Hum. Mol. Genet. (2004) [Pubmed]
  8. Sim2 mutants have developmental defects not overlapping with those of Sim1 mutants. Goshu, E., Jin, H., Fasnacht, R., Sepenski, M., Michaud, J.L., Fan, C.M. Mol. Cell. Biol. (2002) [Pubmed]
  9. Reflex-mediated desquamation of bronchiolar epithelium in guinea pigs exposed acutely to sulfuric acid aerosol. Brownstein, D.G. Am. J. Pathol. (1980) [Pubmed]
  10. Adherent neutrophils mediate permeability after atelectasis. Goldman, G., Welbourn, R., Rothlein, R., Wiles, M., Kobzik, L., Valeri, C.R., Shepro, D., Hechtman, H.B. Ann. Surg. (1992) [Pubmed]
  11. Atelectasis and chest wall shape during halothane anesthesia. Warner, D.O., Warner, M.A., Ritman, E.L. Anesthesiology (1996) [Pubmed]
  12. Sodium nitroprusside increases Qs/Qt in dogs with regional atelectasis. Colley, P.S., Cheney, F.W. Anesthesiology (1977) [Pubmed]
  13. Bilateral intraoperative atelectasis in a child with latex allergy. Gebhard, R., Pivalizza, E.G., Nasri, S., Chelly, J.E. Anesthesiology (2000) [Pubmed]
  14. Insufflated halothane increases venous admixture less than nitroprusside in canine atelectasis. Johnson, D., Hurst, T., Mayers, I. Anesthesiology (1992) [Pubmed]
  15. Lack of efficacy of intrapleural bupivacaine for postoperative analgesia following thoracotomy. Schneider, R.F., Villamena, P.C., Harvey, J., Surick, B.G., Surick, I.W., Beattie, E.J. Chest (1993) [Pubmed]
  16. Atelectasis and gas exchange after cardiac surgery. Tenling, A., Hachenberg, T., Tydén, H., Wegenius, G., Hedenstierna, G. Anesthesiology (1998) [Pubmed]
  17. Effects of halothane on hypoxic pulmonary vasoconstriction in canine atelectasis. Johnson, D.H., Hurst, T.S., Mayers, I. Anesth. Analg. (1991) [Pubmed]
  18. The yield of flexible fiberoptic bronchoscopy in pediatric intensive care patients. Bar-Zohar, D., Sivan, Y. Chest (2004) [Pubmed]
  19. Bronchial carcinoid tumors in pediatric patients. Wang, L.T., Wilkins, E.W., Bode, H.H. Chest (1993) [Pubmed]
  20. Correlation of gas exchange impairment to development of atelectasis during anaesthesia and muscle paralysis. Hedenstierna, G., Tokics, L., Strandberg, A., Lundquist, H., Brismar, B. Acta anaesthesiologica Scandinavica. (1986) [Pubmed]
  21. Phrenic nerve stimulation during halothane anesthesia. Effects of atelectasis. Hedenstierna, G., Tokics, L., Lundquist, H., Andersson, T., Strandberg, A., Brismar, B. Anesthesiology (1994) [Pubmed]
  22. A randomized, controlled trial to determine the effectiveness of fascial infiltration of bupivacaine in preventing respiratory complications after elective abdominal surgery. Egan, T.M., Herman, S.J., Doucette, E.J., Normand, S.L., McLeod, R.S. Surgery (1988) [Pubmed]
  23. Effects of atelectasis and vascular occlusion on the simultaneous measurement of serotonin and propranolol pulmonary extraction in dogs. Dargent, F., Gardaz, J.P., Morel, P., Suter, P.M., Junod, A.F. Clin. Sci. (1985) [Pubmed]
  24. Radiologic appearance of the Jarvik artificial heart implant and its thoracic complications. Fajardo, L.L., Standen, J.R., Smith, R.G. AJR. American journal of roentgenology. (1988) [Pubmed]
  25. Targeted disruption of NDST-1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice. Fan, G., Xiao, L., Cheng, L., Wang, X., Sun, B., Hu, G. FEBS Lett. (2000) [Pubmed]
  26. Molecular genetic analysis of glucocorticoid and mineralocorticoid signaling in development and physiological processes. Berger, S.A., Cole, T.J., Schmid, W., Schütz, G. Steroids (1996) [Pubmed]
  27. Inhibition of matrix metalloproteinases in gerbil cholesteatoma: preliminary findings. Lehman, D.A., Wilmoth, J.G., Prevatt, A.R., Schultz, G.S., Antonelli, P.J. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. (2002) [Pubmed]
  28. Surfactant use for neonatal lung injury: beyond respiratory distress syndrome. Finer, N.N. Paediatric respiratory reviews. (2004) [Pubmed]
  29. Recurrent pulmonary atelectasis as a manifestation of familial Mediterranean fever. Brauman, A., Gilboa, Y. Arch. Intern. Med. (1987) [Pubmed]
  30. Lung collapse and gas exchange during general anesthesia: effects of spontaneous breathing, muscle paralysis, and positive end-expiratory pressure. Tokics, L., Hedenstierna, G., Strandberg, A., Brismar, B., Lundquist, H. Anesthesiology (1987) [Pubmed]
  31. Effect of high-frequency positive-pressure ventilation on halothane ablation of hypoxic pulmonary vasoconstriction. Hall, S.M., Chapleau, M., Cairo, J., Levitzky, M.G. Crit. Care Med. (1985) [Pubmed]
  32. Pediatric fiberoptic bronchoscopy with a laryngeal mask airway. Nussbaum, E., Zagnoev, M. Chest (2001) [Pubmed]
  33. Pulmonary abnormalities after cardiac surgery are better explained by atelectasis than by increased permeability oedema. Verheij, J., van Lingen, A., Raijmakers, P.G., Spijkstra, J.J., Girbes, A.R., Jansen, E.K., van den Berg, F.G., Groeneveld, A.B. Acta anaesthesiologica Scandinavica. (2005) [Pubmed]
  34. The effect of incisional infiltration of bupivacaine hydrochloride upon pulmonary functions, atelectasis and narcotic need following elective cholecystectomy. Patel, J.M., Lanzafame, R.J., Williams, J.S., Mullen, B.V., Hinshaw, J.R. Surgery, gynecology & obstetrics. (1983) [Pubmed]
WikiGenes - Universities