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Chemical Compound Review

METHYLGUANIDINE     2-methylguanidine

Synonyms: Methylguanidin, AG-K-07651, CHEBI:16628, HMDB01522, LS-7517, ...
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Disease relevance of METHYLGUANIDINE


High impact information on METHYLGUANIDINE


Chemical compound and disease context of METHYLGUANIDINE


Biological context of METHYLGUANIDINE


Anatomical context of METHYLGUANIDINE


Associations of METHYLGUANIDINE with other chemical compounds




Analytical, diagnostic and therapeutic context of METHYLGUANIDINE


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  28. L-gulono-gamma-lactone oxidase is the enzyme responsible for the production of methylguanidine in the rat liver. Fujitsuka, N., Yokozawa, T., Oura, H., Akao, T., Kobashi, K., Ienaga, K., Nakamura, K. Nephron (1993) [Pubmed]
  29. Synthesis and pharmacological evaluation of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers. Hu, L.Y., Guo, J., Magar, S.S., Fischer, J.B., Burke-Howie, K.J., Durant, G.J. J. Med. Chem. (1997) [Pubmed]
  30. N-methyl-D-aspartate receptor activation by guanidinosuccinate but not by methylguanidine: behavioural and electrophysiological evidence. D'Hooge, R., Raes, A., Lebrun, P., Diltoer, M., Van Bogaert, P.P., Manil, J., Colin, F., De Deyn, P.P. Neuropharmacology (1996) [Pubmed]
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  32. Decreased serum antioxidant activity of hemodialysis patients demonstrated by methylguanidine synthesis and microsomal lipid peroxidation. Nagase, S., Aoyagi, K., Hirayama, A., Gotoh, M., Ueda, A., Tomida, C., Kikuchi, H., Takemura, K., Koyama, A. Nephron (1996) [Pubmed]
  33. Site of methylguanidine production and factors that influence production levels. Yokozawa, T., Muto, Y., Wakaki, K., Kashiwagi, H. Nephron (2002) [Pubmed]
  34. Production of methylguanidine from creatinine via creatol by active oxygen species: analyses of the catabolism in vitro. Nakamura, K., Ienaga, K., Yokozawa, T., Fujitsuka, N., Oura, H. Nephron (1991) [Pubmed]
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