Chemical Compound Review:
L-NAME methyl(2S)-2-amino-5-[(amino- nitramido...
Synonyms:
AmbotzHAA5810, Tocris-0665, CHEMBL7890, BSPBio_001221, KBioGR_000561, ...
Scalia,
Coyle,
Levine,
Booth,
Lefer,
Lefer,
Scalia,
Campbell,
Nossuli,
Hayward,
Salamon,
Grayson,
Lefer,
Gobeil,
Zhu,
Brault,
Geha,
Vazquez-Tello,
Fortier,
Barbaz,
Checchin,
Hou,
Nader,
Bkaily,
Gratton,
Heveker,
Ribeiro-da-Silva,
Peri,
Bard,
Chorvatova,
D'Orléans-Juste,
Goetzl,
Chemtob,
Heyman,
Goldfarb,
Shina,
Karmeli,
Rosen,
Kubes,
Schiffrin,
Ziche,
Morbidelli,
Choudhuri,
Zhang,
Donnini,
Granger,
Bicknell,
Schütz,
Andersen,
Tufik,
Dickie,
Roberts,
Lee,
Cotter,
Kaluski,
Milo,
Blatt,
Salah,
Hendler,
Krakover,
Golick,
Vered,
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- Pressure natriuresis in AT(2) receptor-deficient mice with L-NAME hypertension. Obst, M., Gross, V., Janke, J., Wellner, M., Schneider, W., Luft, F.C. J. Am. Soc. Nephrol. (2003)
- Inducible nitric oxide synthase: a little bit of good in all of us. Kubes, P. Gut (2000)
- A role for heterotrimeric GTP-binding proteins and ERK1/2 in insulin-mediated, nitric-oxide-dependent, cyclic GMP production in human umbilical vein endothelial cells. Konopatskaya, O., Shore, A.C., Tooke, J.E., Whatmore, J.L. Diabetologia (2005)
- Apoptosis, coronary arterial remodeling, and myocardial infarction after nitric oxide inhibition in SHR. Ono, Y., Ono, H., Matsuoka, H., Fujimori, T., Frohlich, E.D. Hypertension (1999)
- Influence of temporomandibular joint pain on sleep patterns: role of nitric oxide. Schütz, T.C., Andersen, M.L., Tufik, S. J. Dent. Res. (2004)
- Inhibition of nitric oxide synthase attenuates the development of morphine tolerance and dependence in mice. Majeed, N.H., Przewłocka, B., Machelska, H., Przewłocki, R. Neuropharmacology (1994)
- Nitric oxide synthase inhibition blocks amphetamine-induced locomotor activity in mice. Celik, T., Zaglí, U., Kayír, H., Uzbay, I.T. Drug and alcohol dependence. (1999)
- Effects of phencyclidine on spatial learning and memory: nitric oxide-dependent mechanisms. Wass, C., Archer, T., Pålsson, E., Fejgin, K., Klamer, D., Engel, J.A., Svensson, L. Behav. Brain Res. (2006)
- Correlation between brain nitric oxide synthase activity and opiate withdrawal. Leza, J.C., Lizasoain, I., Cuéllar, B., Moro, M.A., Lorenzo, P. Naunyn Schmiedebergs Arch. Pharmacol. (1996)
- Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo. Luo, Z., Fujio, Y., Kureishi, Y., Rudic, R.D., Daumerie, G., Fulton, D., Sessa, W.C., Walsh, K. J. Clin. Invest. (2000)
- Involvement of calcitonin gene-related peptide in the modulation of human myometrial contractility during pregnancy. Dong, Y.L., Fang, L., Kondapaka, S., Gangula, P.R., Wimalawansa, S.J., Yallampalli, C. J. Clin. Invest. (1999)
- Nitric oxide and cyclic GMP regulate retinal patterning in the optic lobe of Drosophila. Gibbs, S.M., Truman, J.W. Neuron (1998)
- Production and physiological actions of anandamide in the vasculature of the rat kidney. Deutsch, D.G., Goligorsky, M.S., Schmid, P.C., Krebsbach, R.J., Schmid, H.H., Das, S.K., Dey, S.K., Arreaza, G., Thorup, C., Stefano, G., Moore, L.C. J. Clin. Invest. (1997)
- Nitric oxide (NO) modulates the neurogenic control of blood pressure in rats with chronic renal failure (CRF). Ye, S., Nosrati, S., Campese, V.M. J. Clin. Invest. (1997)
- Induction of nitric oxide synthase in the neo-vasculature of experimental tumours in mice. Buttery, L.D., Springall, D.R., Andrade, S.P., Riveros-Moreno, V., Hart, I., Piper, P.J., Polak, J.M. J. Pathol. (1993)
- L-arginine and L-NAME have no effects on the reendothelialization process after arterial balloon injury. Six, I., Van Belle, E., Bordet, R., Corseaux, D., Callebert, J., Dupuis, B., Bauters, C., Bertrand, M.E. Cardiovasc. Res. (1999)
- N-acetylcysteine ameliorates renal microcirculation: studies in rats. Heyman, S.N., Goldfarb, M., Shina, A., Karmeli, F., Rosen, S. Kidney Int. (2003)
- Cellular mechanisms by which adenosine induces vasodilatation in rat skeletal muscle: significance for systemic hypoxia. Bryan, P.T., Marshall, J.M. J. Physiol. (Lond.) (1999)
- Exogenous nitric oxide prevents endotoxin-induced glomerular thrombosis in rats. Westberg, G., Shultz, P.J., Raij, L. Kidney Int. (1994)
- Effect of recombinant human tumor necrosis factor-alpha on cerebral oxygen uptake, cerebrospinal fluid lactate, and cerebral blood flow in the rabbit: role of nitric oxide. Tureen, J. J. Clin. Invest. (1995)
- Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells. Compton, S.A., Elmore, L.W., Haydu, K., Jackson-Cook, C.K., Holt, S.E. Mol. Cell. Biol. (2006)
- A balance between nitric oxide and oxidants regulates mast cell-dependent neutrophil-endothelial cell interactions. Niu, X.F., Ibbotson, G., Kubes, P. Circ. Res. (1996)
- Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells. Kubes, P., Kanwar, S., Niu, X.F., Gaboury, J.P. FASEB J. (1993)
- Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats. Lefer, D.J., Scalia, R., Campbell, B., Nossuli, T., Hayward, R., Salamon, M., Grayson, J., Lefer, A.M. J. Clin. Invest. (1997)
- Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis. Ziche, M., Morbidelli, L., Choudhuri, R., Zhang, H.T., Donnini, S., Granger, H.J., Bicknell, R. J. Clin. Invest. (1997)
- C-peptide inhibits leukocyte-endothelium interaction in the microcirculation during acute endothelial dysfunction. Scalia, R., Coyle, K.M., Levine, B.J., Booth, G., Lefer, A.M. FASEB J. (2000)
- Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells. Zeng, G., Quon, M.J. J. Clin. Invest. (1996)
- Nitric oxide released from activated platelets inhibits platelet recruitment. Freedman, J.E., Loscalzo, J., Barnard, M.R., Alpert, C., Keaney, J.F., Michelson, A.D. J. Clin. Invest. (1997)
- Vasculoprotective role of inducible nitric oxide synthase at inflammatory coronary lesions induced by chronic treatment with interleukin-1beta in pigs in vivo. Fukumoto, Y., Shimokawa, H., Kozai, T., Kadokami, T., Kuwata, K., Yonemitsu, Y., Kuga, T., Egashira, K., Sueishi, K., Takeshita, A. Circulation (1997)
- Nitric oxide signaling via nuclearized endothelial nitric-oxide synthase modulates expression of the immediate early genes iNOS and mPGES-1. Gobeil, F., Zhu, T., Brault, S., Geha, A., Vazquez-Tello, A., Fortier, A., Barbaz, D., Checchin, D., Hou, X., Nader, M., Bkaily, G., Gratton, J.P., Heveker, N., Ribeiro-da-Silva, A., Peri, K., Bard, H., Chorvatova, A., D'Orléans-Juste, P., Goetzl, E.J., Chemtob, S. J. Biol. Chem. (2006)
- Involvement of iNOS-dependent NO production in the stimulation of osteoclast survival by TNF-alpha. Lee, S.K., Huang, H., Lee, S.W., Kim, K.H., Kim, K.K., Kim, H.M., Lee, Z.H., Kim, H.H. Exp. Cell Res. (2004)
- Crucial role of interleukin-1beta and nitric oxide synthase in silica-induced inflammation and apoptosis in mice. Srivastava, K.D., Rom, W.N., Jagirdar, J., Yie, T.A., Gordon, T., Tchou-Wong, K.M. Am. J. Respir. Crit. Care Med. (2002)
- Endothelin and endothelin antagonists in hypertension. Schiffrin, E.L. J. Hypertens. (1998)
- A defect in HIV-1 transgenic murine macrophages results in deficient nitric oxide production. Dickie, P., Roberts, A., Lee, R. J. Leukoc. Biol. (2001)
- Rapid inactivation of NOS-I by lipopolysaccharide plus interferon-gamma-induced tyrosine phosphorylation. Colasanti, M., Persichini, T., Cavalieri, E., Fabrizi, C., Mariotto, S., Menegazzi, M., Lauro, G.M., Suzuki, H. J. Biol. Chem. (1999)
- LINCS: L-NAME (a NO synthase inhibitor) in the treatment of refractory cardiogenic shock: a prospective randomized study. Cotter, G., Kaluski, E., Milo, O., Blatt, A., Salah, A., Hendler, A., Krakover, R., Golick, A., Vered, Z. Eur. Heart J. (2003)
- Tracheal microvascular responses to inhibition of nitric oxide synthesis in anesthetized rats. Corboz, M.R., Ballard, S.T., Inglis, S.K., Taylor, A.E. Am. J. Respir. Crit. Care Med. (1996)
- Endogenous nitric oxide modifies antigen-induced microvascular leakage in sensitized guinea pig airways. Miura, M., Ichinose, M., Kageyama, N., Tomaki, M., Takahashi, T., Ishikawa, J., Ohuchi, Y., Oyake, T., Endoh, N., Shirato, K. J. Allergy Clin. Immunol. (1996)