The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Bayrusil     diethoxy-quinoxalin-2-yloxy- sulfanylidene...

Synonyms: Quinaltaf, Chinalphos, Ekalux, Guinalphos, QUINALPHOS, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Ekalux


High impact information on Ekalux

  • Chlorpyrifos (O,O-diethyl O-3,5,6-trichloro-2 pyridyl phosphorothioate) 20 EC and Quinalphos (O,O-diethyl O-quinoxalin-2-yl phosphorothioate) 25 EC, were applied in groundnut (Arachis hypogaea L.) field as seed treatment at 25ml/kg and soil treatment at 4l/ha in 1998 and 1999 [6].
  • Total bacterial and fungal population after chlorpyrifos and quinalphos treatments in groundnut (Arachis hypogaea L.) soil [7].
  • Testicular and spermatotoxic effects were investigated in rats exposed to technical-grade quinalphos (70%) at dose levels of 0.52 mg kg(-1) (1/50th ld(50)) or 1.04 mg kg(-1) body weight (1/25th ld(50)) for 5 days a week for 60 days [8].
  • In the present set of investigations, the tumorigenic potential of Quinalphos has been evaluated following topical exposure in Swiss albino mice [9].
  • Quinalphos [O,O-diethyl-O-quinoxalinyl-phosphorothidate] is an organophosphorus pesticide with tremendous utility in mixed pest control due to its insecticidal and acaricidal properties [9].

Chemical compound and disease context of Ekalux


Biological context of Ekalux


Anatomical context of Ekalux


Associations of Ekalux with other chemical compounds


Gene context of Ekalux

  • Quinalphos elevated the activities of superoxide dismutase by 30%, (although the increase from 0.24 to 0.31 was physiologically not significant) and catalase by 50% at PND 21, which up on withdrawal of the exposure at PND 22 recovered partially or completely at PND 45 [19].
  • Treatment of quinalphos for 13 days failed to produce any effect on the relative weights of the testes and accessory sex glands [20].

Analytical, diagnostic and therapeutic context of Ekalux


  1. Cytogenetic effects of quinalphos in mice. Rupa, D.S., Reddy, P.P., Reddi, O.S. Food Chem. Toxicol. (1991) [Pubmed]
  2. Role of cytochrome P-450 in quinalphos toxicity: effect on hepatic and brain antioxidant enzymes in rats. Dwivedi, P.D., Das, M., Khanna, S.K. Food Chem. Toxicol. (1998) [Pubmed]
  3. Cytogeneticity of quinalphos and methyl parathion in human peripheral lymphocytes. Rupa, D.S., Reddy, P.P., Reddi, O.S. Human & experimental toxicology. (1990) [Pubmed]
  4. Phototoxicity of quinalphos under sunlight in vitro and in vivo. Srivastava, L.P., Singh, R.P., Raizada, R.B. Food Chem. Toxicol. (1999) [Pubmed]
  5. Studies on the delayed neuropathic and anticholinesterase potential of quinalphos (diethyl 2-quinoxalyl phosphorothionate) in hens. Jokanović, M. Journal of applied toxicology : JAT. (1993) [Pubmed]
  6. Soil dehydrogenase, phosphomonoesterase and arginine deaminase activities in an insecticide treated groundnut (Arachis hypogaea L.) field. Pandey, S., Singh, D.K. Chemosphere (2006) [Pubmed]
  7. Total bacterial and fungal population after chlorpyrifos and quinalphos treatments in groundnut (Arachis hypogaea L.) soil. Pandey, S., Singh, D.K. Chemosphere (2004) [Pubmed]
  8. Testicular and spermatotoxic effects of quinalphos in rats. Pant, N., Srivastava, S.P. Journal of applied toxicology : JAT. (2003) [Pubmed]
  9. Evaluation of carcinogenic and co-carcinogenic potential Quinalphos in mouse skin. Shukla, Y., Singh, A., Mehrotra, N.K. Cancer Lett. (2000) [Pubmed]
  10. Interactions of monocrotophos and quinalphos with Anabaena torulosa isolated from rice soil. Bhaskar, M., Sreenivasulu, C., Venkateswarlu, K. Biochem. Int. (1992) [Pubmed]
  11. Functional impairment of blood-brain barrier following pesticide exposure during early development in rats. Gupta, A., Agarwal, R., Shukla, G.S. Human & experimental toxicology. (1999) [Pubmed]
  12. Assessment of the no-observed-effect level (NOEL) of quinalphos in pregnant rats. Srivastava, M.K., Raizada, R.B. Food Chem. Toxicol. (1999) [Pubmed]
  13. Study of quinalphos (an environmental oestrogenic insecticide) formulation (Ekalux 25 E.C.)-induced damage of the testicular tissues and antioxidant defence systems in Sprague-Dawley albino rats. Debnath, D., Mandal, T.K. Journal of applied toxicology : JAT. (2000) [Pubmed]
  14. Quinalphos-induced suppression of spermatogenesis, plasma gonadotrophins, testicular testosterone production, and secretion in adult rats. Ray, A., Chatterjee, S., Ghosh, S., Bhattacharya, K., Pakrashi, A., Deb, C. Environmental research. (1992) [Pubmed]
  15. Histopathological changes induced by quinalphos in the testes and liver of Indian dessert gerbils, Meriones hurrianae (Jerdon). Sarin, K., Saxena, A.K. Toxicology (1978) [Pubmed]
  16. Fetotoxic response of technical quinalphos in rats. Srivastava, M.K., Raizada, R.B., Dikshith, T.S. Veterinary and human toxicology. (1992) [Pubmed]
  17. Carbamate and organophosphate resistance in cotton pests in India, 1995 to 1999. Kranthi, K.R., Jadhav, D.R., Wanjari, R.R., Ali, S.S., Russell, D. Bull. Entomol. Res. (2001) [Pubmed]
  18. Effects of of habitats and pesticides on aerobic capacity and survival of soil fauna. Tripathi, G., Sharma, B.M. Biomed. Environ. Sci. (2005) [Pubmed]
  19. Effects of neonatal quinalphos exposure and subsequent withdrawal on free radical generation and antioxidative defenses in developing rat brain. Gupta, A., Gupta, A., Shukla, G.S. Journal of applied toxicology : JAT. (1998) [Pubmed]
  20. Effect of quinalphos on testicular steroidogenesis in rats. Ray, A., Chatterjee, S., Bagchi, P., Das, T.K., Deb, C. Andrologia (1988) [Pubmed]
  21. Effect of repeated oral administration of quinalphos on blood esterases in Bubalus bubalis. Srivastava, A.K., Paul, B.S., Malik, J.K. Toxicol. Lett. (1983) [Pubmed]
  22. Suppressive effect of quinalphos on the activity of accessory sex glands and plasma concentrations of gonadotrophins and testosterone in rats. Ray, A., Chatterjee, S., Ghosh, S., Kabir, S.N., Pakrashi, A., Deb, C. Arch. Environ. Contam. Toxicol. (1991) [Pubmed]
WikiGenes - Universities