Chemical Compound Review:
BQ 788 sodium (2R)-2-[[(2R)-2-amino-3-(1...
Synonyms:
- Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788. Ishikawa, K., Ihara, M., Noguchi, K., Mase, T., Mino, N., Saeki, T., Fukuroda, T., Fukami, T., Ozaki, S., Nagase, T. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Impaired response of the denervated kidney to endothelin receptor blockade in normotensive and spontaneously hypertensive rats. Girchev, R., Bäcker, A., Markova, P., Kramer, H.J. Kidney Int. (2004)
- Responses to neither exogenous nor endogenous endothelin-1 are altered in patients with hypercholesterolemia. Boak, L.M., Dart, A.M., Duffy, S.J., Chin-Dusting, J.P. J. Lipid Res. (2005)
- Endothelin-1 enhances glutamate-induced retinal cell death, possibly through ETA receptors. Kobayashi, T., Oku, H., Fukuhara, M., Kojima, S., Komori, A., Ichikawa, M., Katsumura, K., Kobayashi, M., Sugiyama, T., Ikeda, T. Invest. Ophthalmol. Vis. Sci. (2005)
- Prolonged endothelin B receptor blockade causes pulmonary hypertension in the ovine fetus. Ivy, D.D., Parker, T.A., Abman, S.H. Am. J. Physiol. Lung Cell Mol. Physiol. (2000)
- Role of endothelin receptor subtypes in the behavioral effects of the intracerebroventricular administration of endothelin-1 in conscious rats. Nagasaka, J., Tsuji, M., Takeda, H., Matsumiya, T. Pharmacol. Biochem. Behav. (1999)
- Systemic hypertension induced by hepatic overexpression of human preproendothelin-1 in rats. Niranjan, V., Télémaque, S., deWit, D., Gerard, R.D., Yanagisawa, M. J. Clin. Invest. (1996)
- Prostaglandin E2 abrogates endothelin-induced vasoconstriction in renal outer medullary descending vasa recta of the rat. Silldorff, E.P., Yang, S., Pallone, T.L. J. Clin. Invest. (1995)
- Regulation of guinea pig intestinal peristalsis by endogenous endothelin acting at ET(B) receptors. Shahbazian, A., Holzer, P. Gastroenterology (2000)
- Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade. Verhaar, M.C., Strachan, F.E., Newby, D.E., Cruden, N.L., Koomans, H.A., Rabelink, T.J., Webb, D.J. Circulation (1998)
- Effect of selective blockade of endothelin ETB receptors on the liver dysfunction and injury caused by endotoxaemia in the rat. Ruetten, H., Thiemermann, C. Br. J. Pharmacol. (1996)
- Trigeminal nerve ganglion stimulation-induced neurovascular reflexes in the anaesthetized cat: role of endothelin(B) receptors in carotid vasodilatation. Raval, P., Bingham, S., Aiyar, N., Elliott, J.D., Hunter, A.J., Ohlstein, E.H., Parsons, A.A. Br. J. Pharmacol. (1999)
- Orofacial cold hyperalgesia due to infraorbital nerve constriction injury in rats: reversal by endothelin receptor antagonists but not non-steroidal anti-inflammatory drugs. Chichorro, J.G., Zampronio, A.R., Souza, G.E., Rae, G.A. Pain (2006)
- Stretch-induced endothelin B receptor-mediated apoptosis in vascular smooth muscle cells. Cattaruzza, M., Dimigen, C., Ehrenreich, H., Hecker, M. FASEB J. (2000)
- Systemic blockade of the endothelin-B receptor increases peripheral vascular resistance in healthy men. Strachan, F.E., Spratt, J.C., Wilkinson, I.B., Johnston, N.R., Gray, G.A., Webb, D.J. Hypertension (1999)
- Inhibition of in vitro enteric neuronal development by endothelin-3: mediation by endothelin B receptors. Wu, J.J., Chen, J.X., Rothman, T.P., Gershon, M.D. Development (1999)
- Human monocyte adhesion is modulated by endothelin B receptor-coupled nitric oxide release. King, J.M., Srivastava, K.D., Stefano, G.B., Bilfinger, T.V., Bahou, W.F., Magazine, H.I. J. Immunol. (1997)
- Endothelin receptor antagonists inhibit antigen-induced lung inflammation in mice. Fujitani, Y., Trifilieff, A., Tsuyuki, S., Coyle, A.J., Bertrand, C. Am. J. Respir. Crit. Care Med. (1997)
- Endothelin adrenocortical secretagogue effect is mediated by the B receptor in rats. Belloni, A.S., Rossi, G.P., Andreis, P.G., Neri, G., Albertin, G., Pessina, A.C., Nussdorfer, G.G. Hypertension (1996)
- Modification of blood flow in the HSN tumour and normal tissues of the rat by the endothelin ET(B) receptor agonist, IRL 1620. Bell, K.M., Chaplin, D.J., Poole, B.A., Prise, V.E., Tozer, G.M. Int. J. Cancer (1999)
- Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer. Nelson, J.B., Chan-Tack, K., Hedican, S.P., Magnuson, S.R., Opgenorth, T.J., Bova, G.S., Simons, J.W. Cancer Res. (1996)
- Thrombin receptor activation inhibits monocyte spreading by induction of ET(B) receptor-coupled nitric oxide release. Srivastava, K.D., Magazine, H.I. J. Immunol. (1998)
- Endothelin-1 inhibits nitric oxide synthesis in vascular smooth muscle cells. Ikeda, U., Yamamoto, K., Maeda, Y., Shimpo, M., Kanbe, T., Shimada, K. Hypertension (1997)
- Exaggerated coronary vasoreactivity to endothelin-1 in aged rats: role of protein kinase C. Korzick, D.H., Muller-Delp, J.M., Dougherty, P., Heaps, C.L., Bowles, D.K., Krick, K.K. Cardiovasc. Res. (2005)
- Influence of respiratory tract viral infection on endothelin-1-induced potentiation of cholinergic nerve-mediated contraction in mouse trachea. Carr, M.J., Goldie, R.G., Henry, P.J. Br. J. Pharmacol. (1996)
- Functional and binding characterization of endothelin receptors in human bronchus: evidence for a novel endothelin B receptor subtype? Hay, D.W., Luttmann, M.A., Pullen, M.A., Nambi, P. J. Pharmacol. Exp. Ther. (1998)
- Endothelin ETB receptor signaling in the median eminence and subfornical organ of the rat brain. Garrido, M.d.e.l. .R., Israel, A. Neuropeptides (2004)
- Dual control of seminiferous tubule contractility mediated by ETA and ETB endothelin receptor subtypes. Tripiciano, A., Palombi, F., Ziparo, E., Filippini, A. FASEB J. (1997)
- Cocaine- and amphetamine-regulated transcript (CART) peptide: a vasoactive role in the cerebral circulation. Iliff, J.J., Alkayed, N.J., Gloshani, K.J., Traystman, R.J., West, G.A. J. Cereb. Blood Flow Metab. (2005)
- Endothelin-B receptors in cerebral resistance arterioles and their functional significance after focal cerebral ischemia in cats. Touzani, O., Galbraith, S., Siegl, P., McCulloch, J. J. Cereb. Blood Flow Metab. (1997)
- Functional characterization of endothelin receptors in hypertensive resistance vessels. Montagnani, M., Potenza, M.A., Rinaldi, R., Mansi, G., Nacci, C., Serio, M., Vulpis, V., Pirrelli, A., Mitolo-Chieppa, D. J. Hypertens. (1999)