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Chemical Compound Review

Cetrexin     2-dimethylaminoethyl 2-(4...

Synonyms: Acephene, Atsephen, Licidril, Lucidryl, Mucidril, ...
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  1. Meclofenoxate therapy in tardive dyskinesia: a preliminary report. Izumi, K., Tominaga, H., Koja, T., Nomoto, M., Shimizu, T., Sonoda, H., Imamura, K., Igata, A., Fukuda, T. Biol. Psychiatry (1986) [Pubmed]
  2. Centrophenoxine increases the rates of total and mRNA synthesis in the brain cortex of old rats: an explanation of its action in terms of the membrane hypothesis of aging. Zs-Nagy, I., Semsei, I. Exp. Gerontol. (1984) [Pubmed]
  3. Further studies on the effects of centrophenoxine on lipofuscin pigment in neuroblastoma cells in culture: an electron microscopic study. Nandy, K., Baste, C., Schneider, F.H. Exp. Gerontol. (1978) [Pubmed]
  4. Comparative effects of centrophenoxine on the picrotoxin convulsive-seizure threshold in non-irradiated and irradiated mice. Georgiev, V.P., Petkova, B.P. Acta physiologica et pharmacologica Bulgarica. (1978) [Pubmed]
  5. Effect of centrophenoxine on water-immersion restraint stress- and chemically-induced gastric ulcers in rats. Al Moutaery, A.R. Res. Commun. Mol. Pathol. Pharmacol. (2003) [Pubmed]
  6. Habituation of exploratory activity in mice: a screening test for memory enhancing drugs. Platel, A., Porsolt, R.D. Psychopharmacology (Berl.) (1982) [Pubmed]
  7. The quantitative assessment of lipofuscin pigment, cytoplasmic RNA and nucleolar volume in senile dementia. Mann, D.M., Sinclair, K.G. Neuropathol. Appl. Neurobiol. (1978) [Pubmed]
  8. Effects of different drugs on the higher nervous activity in man. Meclophenoxate. Hrbek, J., Macáková, J., Komenda, S., Dostálová, K., Medek, A. Acta Universitatis Palackianae Olomucensis Facultatis Medicae. (1980) [Pubmed]
  9. Some central nervous actions of centrophenoxine (Meclofenoxat) in animals. Safta, L., Cuparencu, B. Acta Biol. Med. Ger. (1978) [Pubmed]
  10. Effects of meclofenoxate and Extr. Rhodiolae roseae L. on electroconvulsive shock-impaired learning and memory in rats. Lazarova, M.B., Petkov, V.D., Markovska, V.L., Petkov, V.V., Mosharrof, A. Methods and findings in experimental and clinical pharmacology. (1986) [Pubmed]
  11. Age-related decline in multiple unit action potentials of CA3 region of rat hippocampus: correlation with lipid peroxidation and lipofuscin concentration and the effect of centrophenoxine. Sharma, D., Maurya, A.K., Singh, R. Neurobiol. Aging (1993) [Pubmed]
  12. Lipofuscin in retinal pigment epithelium of rhesus monkey: lack of diminution with centrophenoxine treatment. Andrews, L.D., Brizzee, K.R. Neurobiol. Aging (1986) [Pubmed]
  13. Effects of cerebro-protective agents on enzyme activities of rat primary glial cultures and rat cerebral cortex. Bielenberg, G.W., Hayn, C., Krieglstein, J. Biochem. Pharmacol. (1986) [Pubmed]
  14. Meclofenoxate decreases protein and albumin synthesis in hepatocytes isolated from old rats. van Bezooijen, C.F., Sakkee, A.N., Knook, D.L. Biochem. Pharmacol. (1983) [Pubmed]
  15. Modulatory effects of centrophenoxine on different regions of ageing rat brain. Bhalla, P., Nehru, B. Exp. Gerontol. (2005) [Pubmed]
  16. Systematic review of cholinergic drugs for neuroleptic-induced tardive dyskinesia: a meta-analysis of randomized controlled trials. Tammenmaa, I.A., Sailas, E., McGrath, J.J., Soares-Weiser, K., Wahlbeck, K. Prog. Neuropsychopharmacol. Biol. Psychiatry (2004) [Pubmed]
  17. Morphometric studies on synapses of the cerebellar glomerulus: the effect of centrophenoxine treatment in old rats. Giuli, C., Bertoni-Freddari, C., Pieri, C. Mech. Ageing Dev. (1980) [Pubmed]
  18. Comparative studies on the effects of the nootropic drugs adafenoxate, meclofenoxate and piracetam, and of citicholine on scopolamine-impaired memory, exploratory behavior and physical capabilities (experiments on rats and mice). Petkov, V.D., Mosharrof, A.H., Petkov, V.V. Acta physiologica et pharmacologica Bulgarica. (1988) [Pubmed]
  19. On acute effects of some drugs on the higher nervous activity in man. Ethanol (0.5 g/kg) and its interaction with diazepam (5 mg) and meclophenoxate (100 mg). Part LVIII. Hrbek, J., Macáková, J., Komenda, S., Siroká, A., Rypka, M. Acta Universitatis Palackianae Olomucensis Facultatis Medicae. (1989) [Pubmed]
  20. Cytotoxic activity of alkylating agents in the presence of centrophenoxine and its hydrolysis products. Sladek, N.E. J. Pharmacol. Exp. Ther. (1977) [Pubmed]
  21. Effect of centrophenoxine on the antioxidative enzymes in various regions of the aging rat brain. Roy, D., Pathak, D.N., Singh, R. Exp. Gerontol. (1983) [Pubmed]
  22. Fluidizing effects of centrophenoxine in vitro on brain and liver membranes from different age groups of mice. Wood, W.G., Gorka, C., Armbrecht, H.J., Williamson, L.S., Strong, R. Life Sci. (1986) [Pubmed]
  23. Effect of centrophenoxin on spermatogenesis in mice. Sliwa, L., Płonka, I., Dubis, K., Kowalczyk, K., Srebro, Z. Folia biologica. (1983) [Pubmed]
  24. Effects of centrophenoxine on lipofuscin in the retinal pigment epithelium of old mice. Dylewski, D.P., Nandy, S., Nandy, K. Neurobiol. Aging (1983) [Pubmed]
  25. Cytochemical interaction of nucleolus and cytoplasm in the Purkinje cells of senile white rats under the influence of centrophenoxine. Patro, I.K., Sharma, S.P. Exp. Gerontol. (1984) [Pubmed]
  26. Effect of centrophenoxine and BCE-001 treatment on lateral diffusion of proteins in the hepatocyte plasma membrane as revealed by fluorescence recovery after photobleaching in rat liver smears. Zs-Nagy, I., Ohta, M., Kitani, K. Exp. Gerontol. (1989) [Pubmed]
  27. Nonlinear estimation of kinetic parameters for solid-state hydrolysis of water-soluble drugs. Yoshioka, S., Uchiyama, M. Journal of pharmaceutical sciences. (1986) [Pubmed]
  28. Stability of solid dosage forms. II. Hydrolysis of meclofenoxate hydrochloride in commercial tablets. Yoshioka, S., Shibazaki, T., Ejima, A. Chem. Pharm. Bull. (1983) [Pubmed]
  29. Effect of CDP-choline on learning and memory processes in rodents. Petkov, V.D., Mosharrof, A.H., Kehayov, R., Petkov, V.V., Konstantinova, E., Getova, D. Methods and findings in experimental and clinical pharmacology. (1992) [Pubmed]
  30. The effects of metabolism improving agents: an electrophysiological study. Yasuhara, M., Naito, H. Int. J. Neurosci. (1980) [Pubmed]
  31. Centrophenoxine activates acetylcholinesterase activity in hippocampus of aged rats. Sharma, D., Singh, R. Indian J. Exp. Biol. (1995) [Pubmed]
  32. Gerontopsychological studies using NAI ('Nürnberger Alters-Inventar') on patients with organic psychosyndrome (DSM III, Category 1) treated with centrophenoxine in a double blind, comparative, randomized clinical trial. Pék, G., Fülöp, T., Zs-Nagy, I. Archives of gerontology and geriatrics. (1989) [Pubmed]
  33. Influence of nootropic drugs on the learning- and memory-impairing effect of diethyldithiocarbamate in albino rats. Genkova, M.G., Lazarova, M.B. Methods and findings in experimental and clinical pharmacology. (1988) [Pubmed]
  34. Quantitative studies of the effects of aging, meclofenoxate, and dihydroergotoxine on intraneuronal lipopigment accumulation in the rat. Dowson, J.H. Exp. Gerontol. (1985) [Pubmed]
  35. Analysis of meclofenoxate and its degradation products by high performance liquid chromatography. Tatsuhara, T., Tabuchi, F. Chem. Pharm. Bull. (1980) [Pubmed]
  36. Effects of centrophenoxine on cholinephosphotransferase activity in maternal and fetal guinea pig lung. Stith, I.E., Nag, S., Mukherjee, S., Das, S.K. Exp. Lung Res. (1989) [Pubmed]
  37. The differential effects of meclofenoxate on memory loss in the elderly. Marcer, D., Hopkins, S.M. Age and ageing. (1977) [Pubmed]
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